Zobrazeno 1 - 10
of 61
pro vyhledávání: '"H. S. Margolius"'
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 271:R1090-R1095
Previous studies have shown that sodium depletion is associated with an increase in renal kallikrein-kinin system activity. This system may play an important role in counterbalancing the renal effects of the renin-angiotensin system. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0bb66d3734031791e2a533dd668fb4
https://doi.org/10.1152/ajpregu.1996.271.4.r1090
https://doi.org/10.1152/ajpregu.1996.271.4.r1090
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The production of tissue kallikrein and the short-circuit current (SCC) response in the human colonic epithelial cell line T84 to bradykinin have been studied. These cells produce true tissue kallikrein and secrete it into the growth medium, and addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8c045ddc022485934620343efdfcb2
https://doi.org/10.1152/ajpcell.1991.261.5.c822
https://doi.org/10.1152/ajpcell.1991.261.5.c822
Publikováno v:
Diabetes. 39:299-304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab740576ba2c25002e98e87944815939
https://doi.org/10.2337/diabetes.39.3.299
https://doi.org/10.2337/diabetes.39.3.299
Publikováno v:
Hypertension. 23:1068-1070
Kinins generated intrarenally probably affect renal function by altering levels of various mediators and messengers, including prostaglandin E2 (PGE2) and cyclic guanosine 3',5'-monophosphate (cGMP). Using a microdialysis technique, we monitored leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d5d66e0c3212f28bc11932cbf98a19
https://doi.org/10.1161/01.hyp.23.6.1068
https://doi.org/10.1161/01.hyp.23.6.1068
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(1)
Extensive research has provided few therapeutic agents for the treatment of septicemia. Bradykinin, an endogenous vasodepressor hormone, is a key mediator in the hypotension seen with septicemia. The present investigation shows that a stable metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d1ba47b1310a4a933610d45c1a9bd7b
https://pubmed.ncbi.nlm.nih.gov/11123364
https://pubmed.ncbi.nlm.nih.gov/11123364
Autor:
H S, Margolius
Publikováno v:
Biological research. 31(3)
Studies of kallikrein-kinin systems since the 1930's have now led to substantial insight into the importance of this vasoactive system in the regulation of cardiovascular and renal function. It now seems clear that before long, these insights will le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed230c8fa619625baa8cd0e7ac34d4fa
https://pubmed.ncbi.nlm.nih.gov/9830500
https://pubmed.ncbi.nlm.nih.gov/9830500
Autor:
H S, Margolius
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 26(2)
Kinins can affect many aspects of cellular function, but their roles in human homeostatic mechanisms and disease are just beginning to be understood. In this brief review, some of the interesting new observations about kallikrein-kinin system charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::589ac511af8c2d6ef4964e88ef9c6b18
https://pubmed.ncbi.nlm.nih.gov/7635529
https://pubmed.ncbi.nlm.nih.gov/7635529
Autor:
B. J. Morris, A G Scicli, R. J. MacDonald, F. Gauthier, H. Fritz, Judith A. Clements, R. A. Bradshaw, Margaret Fahnestock, Robert I. Richards, O. A. Carretero, J. Chao, H. S. Margolius, L. Chao, Torill Berg
Publikováno v:
Recent Progress on Kinins ISBN: 9783034873239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd6981e6166b13adc43ca2e13b5ab68
https://doi.org/10.1007/978-3-0348-7321-5_3
https://doi.org/10.1007/978-3-0348-7321-5_3
Publikováno v:
Journal of Biological Chemistry. 259:8522-8528
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dcda067b6248bbebff7f6f3814355e8
https://doi.org/10.1016/s0021-9258(17)39761-2
https://doi.org/10.1016/s0021-9258(17)39761-2
Publikováno v:
Journal of Histochemistry & Cytochemistry. 27:1567-1576
Kallikrein has been localized in rodent kidney and salivary glands by means of an immunoglobulin-enzyme bridge technique. In sections of kidney, anti-kallikrein antibodies bound to the apical region of certain distal tubule segments in the cortex, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069236d20395065c094b3e8ebbd50f6a
https://doi.org/10.1177/27.12.391993
https://doi.org/10.1177/27.12.391993