Zobrazeno 1 - 10
of 204
pro vyhledávání: '"H. S. Margolius"'
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 271:R1090-R1095
Previous studies have shown that sodium depletion is associated with an increase in renal kallikrein-kinin system activity. This system may play an important role in counterbalancing the renal effects of the renin-angiotensin system. In this study, w
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The production of tissue kallikrein and the short-circuit current (SCC) response in the human colonic epithelial cell line T84 to bradykinin have been studied. These cells produce true tissue kallikrein and secrete it into the growth medium, and addi
Publikováno v:
Diabetes. 39:299-304
Publikováno v:
Hypertension. 23:1068-1070
Kinins generated intrarenally probably affect renal function by altering levels of various mediators and messengers, including prostaglandin E2 (PGE2) and cyclic guanosine 3',5'-monophosphate (cGMP). Using a microdialysis technique, we monitored leve
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(1)
Extensive research has provided few therapeutic agents for the treatment of septicemia. Bradykinin, an endogenous vasodepressor hormone, is a key mediator in the hypotension seen with septicemia. The present investigation shows that a stable metaboli
Autor:
H S, Margolius
Publikováno v:
Biological research. 31(3)
Studies of kallikrein-kinin systems since the 1930's have now led to substantial insight into the importance of this vasoactive system in the regulation of cardiovascular and renal function. It now seems clear that before long, these insights will le
Autor:
H S, Margolius
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 26(2)
Kinins can affect many aspects of cellular function, but their roles in human homeostatic mechanisms and disease are just beginning to be understood. In this brief review, some of the interesting new observations about kallikrein-kinin system charact
Autor:
B. J. Morris, A G Scicli, R. J. MacDonald, F. Gauthier, H. Fritz, Judith A. Clements, R. A. Bradshaw, Margaret Fahnestock, Robert I. Richards, O. A. Carretero, J. Chao, H. S. Margolius, L. Chao, Torill Berg
Publikováno v:
Recent Progress on Kinins ISBN: 9783034873239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd6981e6166b13adc43ca2e13b5ab68
https://doi.org/10.1007/978-3-0348-7321-5_3
https://doi.org/10.1007/978-3-0348-7321-5_3
Publikováno v:
Journal of Biological Chemistry. 259:8522-8528
Publikováno v:
Journal of Histochemistry & Cytochemistry. 27:1567-1576
Kallikrein has been localized in rodent kidney and salivary glands by means of an immunoglobulin-enzyme bridge technique. In sections of kidney, anti-kallikrein antibodies bound to the apical region of certain distal tubule segments in the cortex, to