Zobrazeno 1 - 6
of 6
pro vyhledávání: '"H. S. Maniar"'
Publikováno v:
Genes & Development. 10:2222-2233
Replication Protein A (RPA) is a heterotrimeric single-stranded DNA-binding protein (SSB) found in all eukaryotic cells. RPA is known to be required for many of the same reactions catalyzed by the homotetrameric SSB of bacteria, but its origin, subun
Autor:
Luigi D. Notarangelo, H S Maniar, A. D. B. Webster, Vorechovský I, Hans D. Ochs, Qili Zhu, Lennart Nilsson, David Vetrie, Janusz M. Sowadski, Mauno Vihinen
Publikováno v:
Proceedings of the National Academy of Sciences. 91:12803-12807
X-linked agammaglobulinemia (XLA) is a hereditary defect of B-cell differentiation in man caused by deficiency of Bruton tyrosine kinase (BTK). A three-dimensional model for the BTK kinase domain, based on the core structure of cAMP-dependent protein
Autor:
C I Smith, B Baskin, P Humire-Greiff, J N Zhou, P G Olsson, H S Maniar, P Kjellén, J D Lambris, B Christensson, L Hammarström
Publikováno v:
The Journal of Immunology. 152:557-565
The gene mutated in the human disease, X-linked agammaglobulinemia (XLA), is related to the Src gene family of cytoplasmic protein-tyrosine kinases and is designated Btk (Bruton's agammaglobulinemia tyrosine kinase; formerly Atk/Bpk; the human gene i
Publikováno v:
Karolinska Institutet
It has been suggested that tryptophan 563 is sandwiched between residues R562 and A582 in Bruton's agammaglobulinemia tyrosine kinase (Btk). Mutations of the surrounding residues have been shown to cause X-linked agammaglobulinemia. Substitutions R56
Publikováno v:
Radiation and environmental biophysics. 23(4)
Survival studies on irradiated euoxic E. coli B/r cells in presence of various concentrations of four radioprotecting phenothiazine drugs have been carried out. Maximum radioprotection was obtained at a optimal concentration for each drug and it decr
Autor:
H S, Maniar, B B, Singh
Publikováno v:
Indian journal of experimental biology. 23(2)