Zobrazeno 1 - 10
of 968
pro vyhledávání: '"H. Reeves"'
Autor:
Shuhong Han, Haoyang Zhuang, Yanpeng Diao, Mark Segal, Tanzia Islam Tithi, Weizhou Zhang, Westley H. Reeves
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
Abnormal autophagy regulation is implicated in lupus and other autoimmune diseases. We investigated autophagy in the murine pristane-induced lupus model. Pristane causes monocyte/macrophage-mediated endoplasmic reticulum (ER) stress in lung endotheli
Externí odkaz:
https://doaj.org/article/60e26f3c516c4e28884e4077101f7ddb
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/bca1723336d74a21a9beefff6f50566f
Autor:
Li-Rong Shao, Feng Gao, Viveka Chinnasamy, Yasuhiro Kazuki, Mistuo Oshimura, Roger H. Reeves, Carl E. Stafstrom
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106198- (2023)
Children with Down syndrome (DS, trisomy of chromosome 21) have an increased risk of infantile spasms (IS). As an epileptic encephalopathy, IS may further impair cognitive function and exacerbate neurodevelopmental delays already present in children
Externí odkaz:
https://doaj.org/article/11c1f9952d6547a59d297f251d21842c
Autor:
Dylan C Sarver, Cheng Xu, Susana Rodriguez, Susan Aja, Andrew E Jaffe, Feng J Gao, Michael Delannoy, Muthu Periasamy, Yasuhiro Kazuki, Mitsuo Oshimura, Roger H Reeves, G William Wong
Publikováno v:
eLife, Vol 12 (2023)
The consequences of aneuploidy have traditionally been studied in cell and animal models in which the extrachromosomal DNA is from the same species. Here, we explore a fundamental question concerning the impact of aneuploidy on systemic metabolism us
Externí odkaz:
https://doaj.org/article/3aeea4fdb24949308434aa922bedcafd
Autor:
Anna J. Moyer, Fabian-Xosé Fernandez, Yicong Li, Donna K. Klinedinst, Liliana D. Florea, Yasuhiro Kazuki, Mitsuo Oshimura, Roger H. Reeves
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/99e3b861410d482dab00aa682990760c
Autor:
Dylan C. Sarver, Cheng Xu, Leandro M. Velez, Susan Aja, Andrew E. Jaffe, Marcus M. Seldin, Roger H. Reeves, G. William Wong
Publikováno v:
Molecular Metabolism, Vol 68, Iss , Pp 101666- (2023)
Objective: Trisomy 21 is one of the most complex genetic perturbations compatible with postnatal survival. Dosage imbalance arising from the triplication of genes on human chromosome 21 (Hsa21) affects multiple organ systems. Much of Down syndrome (D
Externí odkaz:
https://doaj.org/article/c0e401788b784ca4b4352f0e13a68cc8
Autor:
Kara J. Pitman, Jonathan W. Moore, Matthias Huss, Matthew R. Sloat, Diane C. Whited, Tim J. Beechie, Rich Brenner, Eran W. Hood, Alexander M. Milner, George R. Pess, Gordan H. Reeves, Daniel E. Schindler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Potential gains in future salmon habitat associated with glacier loss have yet to be quantified. This study projects future gains in Pacific salmon freshwater habitat within western North America by linking a model of glacier mass change for 315 glac
Externí odkaz:
https://doaj.org/article/0b15014ac6144a54b4d358fe8becb36e
Publikováno v:
eLife, Vol 11 (2022)
Pristane causes chronic peritoneal inflammation resulting in lupus, which in C57BL/6 mice is complicated by lung microvascular injury and diffuse alveolar hemorrhage (DAH). Mineral oil (MO) also causes inflammation, but not lupus or DAH. Since monocy
Externí odkaz:
https://doaj.org/article/5f0c01bfa91e45358b45d2d0b13d8132
Autor:
Feng J. Gao, Donna Klinedinst, Fabian-Xosé Fernandez, Bei Cheng, Alena Savonenko, Benjamin Devenney, Yicong Li, Dan Wu, Martin G. Pomper, Roger H. Reeves
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-21 (2021)
Abstract Down syndrome (DS) is the leading genetic cause of intellectual disability and causes early-onset dementia and cerebellar hypoplasia. The prevalence of attention deficit hyperactivity disorder is elevated in children with DS. The aneuploid D
Externí odkaz:
https://doaj.org/article/5b0f251116f24c7bacbfcf25efeb3f91
Autor:
Punita Nagpal, Paul H Reeves, Jeh Haur Wong, Laia Armengot, Keun Chae, Nathaniel B Rieveschl, Brendan Trinidad, Vala Davidsdottir, Prateek Jain, William M Gray, Yvon Jaillais, Jason W Reed
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010375 (2022)
In plants, regulated cell expansion determines organ size and shape. Several members of the family of redundantly acting Small Auxin Up RNA (SAUR) proteins can stimulate plasma membrane (PM) H+-ATPase proton pumping activity by inhibiting PM-associat
Externí odkaz:
https://doaj.org/article/35537a5748bf486c82d54e8cd94f7a85