Zobrazeno 1 - 10
of 138
pro vyhledávání: '"H. Raghuraman"'
Publikováno v:
Current Research in Structural Biology, Vol 7, Iss , Pp 100137- (2024)
KvAP is a prokaryotic Kv channel, which has been widely used as a model system to understand voltage- and lipid-dependent gating mechanisms. In phospholipid membranes, the KvAP-VSD adopts the activated/‘Up’ conformation, whereas the presence of n
Externí odkaz:
https://doaj.org/article/e8a3efcbe96f422bade4c950a1f903a1
Autor:
H. Raghuraman, Anja Böckmann
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/2307bfeb2d9444faa49fafa3f3028077
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101200- (2022)
Summary: Comprehensive understanding of a protein’s function depends on having reliable, sophisticated tools to study protein structural dynamics in physiologically-relevant conditions. Here, we present an effective, robust step-by-step protocol to
Externí odkaz:
https://doaj.org/article/ca385ba551c1428f9a2602e05eeae89b
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Membrane proteins mediate a number of cellular functions and are associated with several diseases and also play a crucial role in pathogenicity. Due to their importance in cellular structure and function, they are important drug targets for ~60% of d
Externí odkaz:
https://doaj.org/article/28e8cb3240e6424d97ba3cd9fc9dc157
Akademický článek
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Autor:
Rupasree Brahma, H. Raghuraman
Publikováno v:
The Journal of Membrane Biology. 255:469-483
Publikováno v:
Biochemical and Biophysical Research Communications. 578:122-128
Membrane solubilization by detergents is a critical step for successful membrane protein purification. Alkyl maltoside detergents such as DDM and DM are very expensive and are commonly used to produce most of the high-quality proteins in stable and f
Autor:
Rupasree Brahma, H. Raghuraman
Publikováno v:
Curr Protoc
Understanding the mechanisms of membrane protein function is critical for biomedical research and drug discovery as membrane proteins constitute ∼30% of the proteins encoded by the genomes of both lower and higher organisms and are targets for two-
Autor:
Rupasree Brahma, H. Raghuraman
Publikováno v:
Emerg Top Life Sci
Protein hydration dynamics plays an important role in many physiological processes since protein fluctuations, slow solvation, and the dynamics of hydrating water are all intrinsically related. Red edge excitation shift (REES) is a unique and powerfu
Autor:
Anindita Das, H. Raghuraman
Publikováno v:
Biophysical Journal. 122:374a