Zobrazeno 1 - 10
of 706
pro vyhledávání: '"H. ROCHEFORT"'
Autor:
Anthony B. El-Khoueiry, J. Wei, N. Kossari, Susan Groshen, D. Tsao-Wei, Y. Xu, G. Morrison, C. Hugen, B. Kao, P. Gill, Amir Goldkorn, H. Rochefort, T. Xu, Yu-Chong Tai
Publikováno v:
European Journal of Cancer. 69:S126-S127
Autor:
Gérard Bréart, V. Ringa, Regine Sitruk-Ware, F. Kuttenn, Pierre-Yves Scarabin, C. Cornu, M.M.C. Sureau, J. Conard, Ph. Bouchard, Claude Dreux, Claude Sureau, H. Rochefort, Maurice Tubiana, Henri Rochefort, H. Sancho-Garnier, J.P. Boissel, H. Rozenbaum, Joël Ménard
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 187:1707-1711
RESUME Les THS compensent l’arret de secretion ovarienne survenant a la menopause en associant un estrogene et un progestatif par voie generale qui protege du risque de cancer de l’endometre. Chez la femme ayant subi une hysterectomie, les risque
Autor:
Jacques Rouëssé, P. Banzet, J. Civatte, F. Darnis, J. Dubousset, R. Küss, H. Laccourreye, B. Launois, J.D. Picard, C. Sureau, G. Blaudin de Thé, P. Tiollais, M. Tubiana, M. Verhaeghe, Messieurs A. Aurengo, J. Bazex, G. Dubois, H. Rochefort, J. Rouëssé, Madame V. Daurat, MM.M. Genève, null Henry-Amar, F. Lemaire, null Maraninchi, J. Ménard, J. Michaud
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 187:1001-1015
RESUME L’Academie Nationale deMedecine considere que la recherche biomedicale, chez l’homme, respectant les regles de l’ethique medicale et de la rigueur scientifique, est un imperatif de Sante Publique. Son encadrement legislatif est necessair
Publikováno v:
Human Reproduction. 11:392-397
The results of histological examination of the endometrium are normal in most patients with unexplained sterility. Cathepsin D is a ubiquitous lysosomal protease regulated by progesterone in the endometrium. Assays of concentrations of cathepsin D mi
Autor:
Marcia I. Dawson, X. S. Li, Barbara A. Conley, Joseph A. Fontana, Z. M. Shao, M. S. Sheikh, H Rochefort, M Garcia, A M Jetten, Suhlan Wu
Publikováno v:
Journal of Biological Chemistry. 269:21440-21447
Retinoids mediate their actions via RARs (retinoic acid receptors) and RXRs (retinoid X receptors). Each class of these nuclear retinoid receptors is further subdivided into three species, namely alpha, beta, and gamma. Recent studies demonstrate tha
Autor:
C. Faul, N. J. O’Higgins, J.-P. Brouillet, D. Reilly, Enda W. McDermott, T. Maudelonde, Michael J. Duffy, James J. Fennelly, H. Rochefort
Publikováno v:
Clinical Chemistry. 38:2114-2116
Cathepsin D (CD) is an aspartyl protease implicated in cancer metastasis. In this study of 331 patients, we show that patients with primary breast carcinomas containing high concentrations of CD have a significantly shorter disease-free interval (chi
Autor:
H, Rochefort
Publikováno v:
Bulletin de l'Academie nationale de medecine. 183(5)
The study of several human estrogen receptor positive breast cancer cell lines has allowed characterization of a number of estrogen-induced proteins (e.g. progesterone receptor, cathepsin D, pS2 and fibulin-1 in ovarian cell lines). In primary tumour
Publikováno v:
International journal of cancer. 80(6)
The mannose-6-phosphate/insulin-like growth-factor-II receptor (M6P/IGFII-R) involved in trafficking of newly synthesized lysosomal enzymes, degradation of IGFII and activation of TGFbetaI, was suggested as being coded by a tumor-suppressor gene. No
Autor:
P, Pujol, J M, Rey, P, Nirde, P, Roger, M, Gastaldi, F, Laffargue, H, Rochefort, T, Maudelonde
Publikováno v:
Cancer research. 58(23)
Although estrogen receptor (ER)-alpha is expressed in both benign and malignant ovarian tumors, the role of ER in ovarian carcinogenesis of epithelial tumors is still unknown. In view of the recent characterization of ER-beta, a second form of ER tha
Autor:
H, Rochefort
Publikováno v:
Comptes rendus des seances de la Societe de biologie et de ses filiales. 192(2)
This short review presents the current stage of knowledge of our laboratory on the mechanism of action of cathepsin D and estrogens on tumor progression, mostly based on studies of human breast and ovarian cancer cell lines. Cathepsin D (cath-D) over