Zobrazeno 1 - 10
of 102
pro vyhledávání: '"H. R. Schelbert"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 266:H1304-H1315
To develop a compartmental model for estimating myocardial oxygen consumption rate (MVO2) with [1-11C]acetate, the metabolic fate of radiolabeled acetate was determined in normoxic and ischemic conditions in isolated perfused rat hearts. Glutamate co
Publikováno v:
Scopus-Elsevier
Radiolabeled monoclonal antibody fragments to myosin, specifically 111In-labeled antimyosin, have been shown to be effective for imaging areas of myocardial infarct. To determine if 111In-labeled antimyosin can be used to assess the extent of necrosi
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(1)
In patients with coronary artery disease (CAD), mental stress may provoke ischemic electrocardiograph changes and abnormalities in regional and global left ventricular function. However, little is known about the underlying myocardial blood flow resp
Autor:
Y, Choi, S C, Huang, R A, Hawkins, J Y, Kim, B T, Kim, C K, Hoh, K, Chen, M E, Phelps, H R, Schelbert
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(6)
Several tracer kinetic methods have been proposed for quantification of regional myocardial blood flow (MBF) with 13N-ammonia and PET. Merits and limitations specific to each approach, however, generally are not clear, because they have not been eval
Publikováno v:
Journal of the American College of Cardiology. 33(5)
The purpose of this study was to evaluate the predictive accuracy of positron emission tomography (PET) blood flow-F-18 fluorodeoxyglucose (FDG) imaging in coronary artery disease (CAD) patients with diabetes mellitus (DM).Positron emission tomograph
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(7)
Autor:
K T, Sun, K, Chen, S C, Huang, D B, Buxton, H W, Hansen, A S, Kim, S, Siegel, Y, Choi, P, Müller, M E, Phelps, H R, Schelbert
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(3)
Although [1-11C]acetate has been validated as a PET tracer for myocardial oxygen consumption (MVO2) in animals and humans, mono- and biexponential fitting of the tissue time-activity curve yields only estimates of MVO2. This study attempts to develop
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 37(10)
The extraction of pure arterial time-activity curves (TACs) from dynamic PET images of a small animal heart using factor analysis of dynamic structures (FADS) was found to be unsuccessful due to the small size of the cardiac chamber that causes exten
Autor:
H R, Schelbert
Publikováno v:
American journal of cardiac imaging. 10(3)
Publikováno v:
American journal of cardiac imaging. 10(3)
Increases in wall stress because of left ventricular enlargement and/or alterations in coronary vasomotor tone might affect myocardial blood flow and vasodilatory capacity in patients with dilated cardiomyopathy. To test this hypothesis myocardial bl