Zobrazeno 1 - 10
of 45
pro vyhledávání: '"H. R. Brashear"'
Autor:
K V, Papp, H, Rofael, A E, Veroff, M C, Donohue, S, Wang, C, Randolph, E, Grober, H R, Brashear, G, Novak, K, Ernstrom, R, Raman, P S, Aisen, R, Sperling, G, Romano, D, Henley
Publikováno v:
The Journal Of Prevention of Alzheimer's Disease.
Cognitive composites commonly serve as primary outcomes in Alzheimer's disease (AD) secondary prevention trials.To evaluate the association between amyloid (Aβ) burden level (+/-) and performance on three separate composite endpoints: Preclinical Al
Publikováno v:
The Journal Of Prevention of Alzheimer's Disease. :1-9
Background: The Neuropsychological Test Battery (NTB) is a combination of widely used clinical neuropsychological tests measuring memory and executive function and was designed to overcome some of the limitations of the traditionally used Alzheimer
Autor:
Parthenia Giannakopoulou, T. Andrews, Geraint Price, D. Perera, Lefkos T. Middleton, Michael T. Ropacki, Bowen Su, Nzeera Ketter, Heather Ward, Lisa Curry, Josip Car, H. M. Arrighi, Catherine Robb, Chinedu T. Udeh-Momoh, Darina Bassil, H. R. Brashear, Gerald Novak, Martin Cohn, Robert Perneczky
Publikováno v:
The journal of prevention of Alzheimer's disease 6(4), 256-266 (2019). doi:10.14283/JPAD.2019.31
Background: The CHARIOT PRO Main study is a prospective, non-interventional study evaluating cognitive trajectories in participants at the preclinical stage of Alzheimer’s disease (AD) classified by risk levels for developing mild cognitive impairm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c825f42e577116d7cdf5f8b151134483
Autor:
Nzeera Ketter, Enchi Liu, A Shadman, J Werth, J Di, M Lu, G Novak, G LePrince Leterme, H R Brashear, L S Honig
Publikováno v:
The Journal of Prevention of Alzheimer's Disease. :1-10
Background: Vanutide Cridificar (ACC-001), a novel investigational immunotherapeutic vaccine designed to elicit antibodies against the N-terminal peptide 1-7 of the amyloid-beta peptide, believed to be important in the pathogenesis of Alzheimer’s d
Autor:
D. Melançon, Kristen Morris, Achim Gass, Ronald Black, H. M. Arrighi, G. Rippon, Y. Lu, Stephen Salloway, Y. Miaux, Clifford R. Jack, Donatella Tampieri, H. R. Brashear, Reisa A. Sperling, Jerome Barakos, Michael Grundman, Jochen B. Fiebach
Publikováno v:
AJNR Am J Neuroradiol
BACKGROUND AND PURPOSE: AD is one of the few leading causes of death without a disease-modifying drug; however, hopeful agents are in various phases of development. MR imaging abnormalities, collectively referred to as amyloid-related imaging abnorma
Autor:
B, Winblad, S, Gauthier, L, Scinto, H, Feldman, G K, Wilcock, L, Truyen, A J, Mayorga, D, Wang, H R, Brashear, J S, Nye, K, Wilks
Publikováno v:
Neurology
Objective: To assess the safety of galantamine in subjects with mild cognitive impairment (MCI), the ability of galantamine to benefit cognition and global functioning in subjects with MCI, and the ability of galantamine to delay conversion to dement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ccf58fb0a0eca580496c66dfb7b404
https://ora.ox.ac.uk/objects/uuid:5acd7361-9904-4f03-8656-f729a4251792
https://ora.ox.ac.uk/objects/uuid:5acd7361-9904-4f03-8656-f729a4251792
Autor:
H R Brashear, Stephen Salloway, Alexander P. Auchus, Amos D. Korczyn, C Gassmann-Mayer, P.P. De Deyn
Publikováno v:
Neurology
To evaluate efficacy and safety of galantamine for patients with vascular dementia (VaD).In this multinational, randomized, double-blind, placebo-controlled, parallel-group clinical trial, 788 patients with probable VaD who also satisfied strict cent
Autor:
Kurt A. Jaeckle, J.Y. Delattre, K. Tanaka, J.W.B. Moll, H. R. Brashear, M. Drlicek, J. Honnorat, Charles J. Vecht, Edward J. Dropcho, J. C. Antoine, Francesc Graus, John E. Greenlee, B. Giometto
Publikováno v:
Neurology. 45:1937-1941
Paraneoplastic syndromes of the central nervous system (PNS) consist of a variety of neurologic disorders including encephalomyelitis (limbic encephalitis, brainstem encephalitis, and acute myelitis), sensory neuronopathy, subacute cerebellar degener
Publikováno v:
Current Alzheimer Research
Background: This analysis aimed to identify an operational, clinically relevant definition of response achieved in short-term clinical trials to support the identification of patients with Alzheimer’s disease (AD) who would benefit most from long-t
Autor:
H. R. Brashear, G. F. Wooten, Carol A. Manning, M. Fowler, P. Damgaard, M.B.S. Lopes, J. W. Mandell, Bradley Miller, Russell H. Swerdlow
Publikováno v:
Neurology. 72(3)
Objective: To describe a multigenerational kindred with a frontotemporal dementia clinical syndrome (FTDS), extensive subcortical gliosis pathology, and autosomal dominant genetics. Methods: Clinical, imaging, and pathologic evaluations of multiple f