Synthetic oxytocics V. Quinine derivatives

Autor: H. Pouwels, H. Veldstra

Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 74:795-804

Contrary to expectations, based upon a certain structural resemblance between 3-(piperidyl-(2)-methyl-)indoles (II) and quinine (III), the change from quinine and related alkaloids to their 9-deoxy bases (via the 9-chloro-9-deoxy derivatives) does no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0509282b62d2713528b968b9de3e47d0
https://doi.org/10.1002/recl.19550740704

Structural and Functional Analysis of the S-layer Protein Crystallisation Domain of Lactobacillus acidophilus ATCC 4356: Evidence for Protein–Protein Interaction of two Subdomains

Autor: Peter H. Pouwels, Dennis Jager, Beatriz Martínez, Egbert Smit, Frans J. Tielen

Publikováno v: Journal of Molecular Biology. 324:953-964

The structure of the crystallisation domain, SAN, of the S A-protein of Lactobacillus acidophilus ATCC 4356 was analysed by insertion and deletion mutagenesis, and by proteolytic treatment. Mutant S A-protein synthesised in Escherichia coli with 7-13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9478a00c3b961b51019a8f6206caaa28
https://doi.org/10.1016/s0022-2836(02)01135-x

Gut-associated lactobacilli for oral immunisation

Autor: Jos F.M.L. Seegers, Peter H. Pouwels, Carin E.G Havenith

Publikováno v: Food Research International. 35:151-163

Lactobacilli have a number of properties which render them highly suited as vehicles for the delivery to the mucosa of compounds that are of pharmaceutical interest. Many strains of the genus Lactobacillus are capable of colonising specific regions o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8ebb0c8e973252bc7b93b8fefb7fb12
https://doi.org/10.1016/s0963-9969(01)00177-6

Engineering the microflora to vaccinate the mucosa: serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C-expressing lactobacilli

Autor: R.J. Leer, B. GaerthÉ, C. Smittenaar, F. J. Tielen, J.E.R. Thole, J. G. M. M. Van Der Stap, M.J. Heijne Den Bak-Glashouwer, Peter H. Pouwels, D. M. Shaw, C.E.G. Havenith

Publikováno v: Immunology. 100:510-518

The delivery of antigens to mucosal-associated lymphoid tissues in paediatric and immunocompromised populations by safe, non-invasive vectors, such as commensal lactobacilli, represents a crucial improvement to prevailing vaccination options. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab74ad96b0c28b5a73e8ba4a68a410f3
https://doi.org/10.1046/j.1365-2567.2000.00069.x

Cloning, Sequence Analysis, and Characterization of the Genes Involved in Isoprimeverose Metabolism in Lactobacillus pentosus

Autor: R.J. Leer, B.C. Lokman, Pieter W. Postma, Peter H. Pouwels, Stéphane Chaillou, C. Posthuma

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 1998, 180 (9), pp.2312-2320. ⟨10.1128/JB.180.9.2312-2320.1998⟩
Journal of Bacteriology, 9, 180, 2312-2320

Two genes, xylP and xylQ , from the xylose regulon of Lactobacillus pentosus were cloned and sequenced. Together with the repressor gene of the regulon, xylR , the xylPQ genes form an operon which is inducible by xylose and which is transcribed from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a6e581585d87fa68313828616eaa17
https://doi.org/10.1128/jb.180.9.2312-2320.1998