Zobrazeno 1 - 10
of 322
pro vyhledávání: '"H. Pilz"'
Autor:
Günter Päth, Ingo H. Pilz, Jochen Seufert, Ines Sommerer, AE Mehana, M Alt, J Baumann, Albrecht Hoffmeister
Publikováno v:
Am J Physiol Endocrinol Metab
Obesity is associated with dyslipidemia and subclinical inflammation that promotes metabolic disturbances including insulin resistance and pancreatic β-cell dysfunction. The nuclear protein, transcriptional regulator 1 (NUPR1) responds to cellular s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7682a36c661373b6388e29e632faf1
https://europepmc.org/articles/PMC7473916/
https://europepmc.org/articles/PMC7473916/
Autor:
Hagen Schmal, Alexander T. Mehlhorn, Ingo H. Pilz, David Dovi-Akue, Christina Kirchhoff, Norbert P. Südkamp, Ulrike Gerlach, Christian Lohrmann, Philipp Niemeyer
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
Introduction. Although it is well known that BMP-2 and BMP-7 play significant roles in cartilage metabolism, data about intra-articular expression and localization of these proteins and their receptors in humans are rare. Methods. Biopsies of synovia
Externí odkaz:
https://doaj.org/article/4a0b72b247a04ef7953525763d47a329
Autor:
Philipp Niemeyer, Ingo H. Pilz, Ulrike V. Gerlach, Norbert P. Südkamp, Alexander T. Mehlhorn, David Dovi-Akue, Hagen Schmal, Christina Kirchhoff
Publikováno v:
Cytotherapy. 14:868-876
Background aims. Bone morphogenetic protein-2 (BMP-2) and its receptor type 1A (BMPR-1A) play signifi cant roles in cartilage metabolism. The aim of this study was to evaluate a possible correlation between intra-articular expression of these protein
Publikováno v:
Experimental Hematology. 38:792-797
Objective RNA interference mediated by transcription of short hairpin RNAs (shRNAs) from lentiviral expression vectors has emerged as an efficient method to effectively and specifically silence gene expression in a vast variety of mammalian cells. sh
Autor:
Ingo H. Pilz, Heike L. Pahl, Britta Will, Roland Roelz, Anna Rita Migliaccio, Angela S. Magin, Daniel H. Schanne, Manuel Mutschler, Martina Buerge
Publikováno v:
British Journal of Haematology. 146:203-217
The transcription factor Nuclear Factor-Erythroid 2 (NF-E2) is overexpressed in the vast majority of patients with polycythaemia vera (PV). In murine models, NF-E2 overexpression increases proliferation and promotes cellular viability in the absence
Autor:
Karim Zaoui, Sandra Braun, Kerstin Schwarzwaelder, Claudia R. Ball, Hanno Glimm, Ingo H. Pilz, Manfred Schmidt, Christof von Kalle, Cynthia C. Bartholomae
Publikováno v:
Nature Methods. 4:1051-1057
Integrating vector systems used in clinical gene therapy have proven their therapeutic potential in the long-term correction of immunodeficiencies1,2,3,4. The integration loci of such vectors in the cellular genome represent a molecular marker unique
Autor:
Ingo H. Pilz, Manfred Schmidt, Christof von Kalle, Sylvia Fessler, Hanno Glimm, David A. Williams, Claudia R. Ball
Publikováno v:
Blood. 110:1779-1787
Efficient in vivo selection increases survival of gene-corrected hematopoietic stem cells (HSCs) and protects hematopoiesis, even if initial gene transfer efficiency is low. Moreover, selection of a limited number of transduced HSCs lowers the number
Autor:
Steffen, Kissling, Michael, Seidenstuecker, Ingo H, Pilz, Norbert P, Suedkamp, Hermann O, Mayr, Anke, Bernstein
Publikováno v:
BMC Biotechnology
Background Tissue engineering and bone substitutes are subjects of intensive ongoing research. If the healing of bone fractures is delayed, osteoinductive materials that induce mesenchymal stem cells (MSCs) to form bone are necessary. The use of Bone
Autor:
David Dovi-Akue, Ingo H. Pilz, Ralf Henkelmann, Gian M. Salzmann, Hagen Schmal, Norbert P. Südkamp
Publikováno v:
International orthopaedics. 39(8)
There is still a lack of reliable data on cytokine concentrations in the ankle and their value for prognosis. In a prospective clinical trial, lavage fluids were collected from 49 patients with an arthroscopy of the ankle. The fluids were investigate