Zobrazeno 1 - 10
of 147
pro vyhledávání: '"H. Peter Lu"'
Autor:
H. Peter Lu
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 6, p 145 (2023)
Fluctuations in mechanical force vectors within living cells can substantially influence the behavior and functions of proteins. Tau protein can spontaneously be raptured and entangled in refolding under picoNewton compressive forces that are biologi
Externí odkaz:
https://doaj.org/article/3e25c73838c84e829cc41bf4640b8ed4
Autor:
S. Roy Chowdhury, H. Peter Lu
Publikováno v:
Chemical Physics Impact, Vol 4, Iss , Pp 100060- (2022)
Recent studies have indicated that tau protein aggregation is closely related to Alzheimer's disease. Though the later stages of the aggregation process are extensively studied, it is still unknown how the aggregation occurs in the earliest stage. It
Externí odkaz:
https://doaj.org/article/74ce943ce67c4eeabfcd79b83a044b0e
Autor:
Achut P. Silwal, H. Peter Lu
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 14849-14857 (2018)
Externí odkaz:
https://doaj.org/article/f7465210267443cc97cca02200a9868c
Publikováno v:
The journal of physical chemistry. B.
Force manipulation on the biological entities from living cells to protein molecules has revealed many mechanical details of cell biology from resolving folding and unfolding pathways to finding molecular interaction forces. A nucleosome is the basic
Autor:
H. Peter Lu, S. Roy Chowdhury, Kaustav Dey, Joseph Shinar, Ruth Shinar, Pavel Anzenbacher, Erik Dykstra
Publikováno v:
ACS Applied Electronic Materials. 3:3365-3371
Autor:
Pavel Anzenbacher, H. Peter Lu, Erik Dykstra, S. Roy Chowdhury, Kaustav Dey, Ruth Shinar, Aleksandr Koronatov, Joseph Shinar
Publikováno v:
Journal of Materials Chemistry C. 8:11988-11996
The fabrication of solution deposited OLEDs is fraught with difficulties, largely due to the interlayer mixing and surface erosion during sequential deposition of the layers. We demonstrate that these problems can be circumvented by using photopolyme
Publikováno v:
The Journal of chemical physics. 156(5)
Conformational dynamics play a crucial role in protein functions. A molecular-level understanding of the conformational transition dynamics of proteins is fundamental for studying protein functions. Here, we report a study of real-time conformational
Publikováno v:
Biophys J
Mechanisms that regulate nitric oxide synthase enzymes (NOS) are of interest in biology and medicine. Although NOS catalysis relies on domain motions and is activated by calmodulin (CaM) binding, the relationships are unclear. We used single-molecule
Publikováno v:
Physical chemistry chemical physics : PCCP. 22(3)
Mechanical force plays a critical role in the relationship between protein structure and function. Force manipulation by Atomic Force Microscope can be significant and trigger chemical and biological activities of proteins. Previously we have reporte
Autor:
H. Peter Lu, Achut P. Silwal
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 14849-14857 (2018)
ACS Omega
ACS Omega
The selective interaction of signaling compounds including neurotransmitters and drugs with the dopamine receptors (DARs) is extremely important for the treatment of neurodegenerative diseases. Here, we report a method to probe the selective interact