Zobrazeno 1 - 10
of 592
pro vyhledávání: '"H. Pauly"'
Autor:
Kelsi Swope, Josh Morton, Gregory P. Pogue, Leigh Burden, Nicholas Partain, Steve Hume, John Shepherd, Carrie A. Simpson, Miles B. Brennan, Thomas C. Furman, Sheila Kingrey-Gebe, Theresa Martinez, Jim McDonough, Michael H. Pauly, Kevin J. Whaley, Larry Zeitlin, Barry Bratcher, Hugh Haydon
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The ongoing SARS-CoV-2 coronavirus pandemic of 2020–2021 underscores the need for manufacturing platforms that can rapidly produce monoclonal antibody (mAb) therapies. As reported here, a platform based on Nicotiana benthamiana produced mAb therape
Externí odkaz:
https://doaj.org/article/0444f122130744d095e196c092b78bd8
Autor:
Thomas H. Pauly
This compelling blend of biography and cultural history depicts five important yet nearly forgotten athletes from the late nineteenth and early twentieth centuries who had a transformative effect on their sports and on the evolution of sports in gene
Autor:
Thomas H. Pauly
Zane Grey was a disappointed aspirant to major league baseball and an unhappy dentist when he belatedly decided to take up writing at the age of thirty. He went on to become the most successful American author of the 1920s, a significant figure in th
Akademický článek
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Autor:
Isak Gerber, Rachel Chikwamba, Stoyan Stoychev, Tsepo L. Tsekoa, Jinal Bhiman, Lukas Mach, Kabamba Alexandra, Lusisizwe Kwezi, Herta Steinkellner, Advaita Acarya Singh, Kevin J. Whaley, Larry Zeitlin, Michael H. Pauly, Juan Vorster, Ofentse Jacob Pooe, Lynn Morris, Therese Lotter-Stark
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Broadly neutralising antibodies (bNAbs) against human immunodeficiency virus type 1 (HIV-1), such as CAP256-VRC26 are being developed for HIV prevention and treatment. These Abs carry a unique but crucial post-translational modification (PTM), namely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b19686c642bd96196e5cfdf45a61d39
http://link.springer.com/article/10.1038/s41598-020-63052-1
http://link.springer.com/article/10.1038/s41598-020-63052-1
Autor:
Ramon A. Ortiz, Natasha Bohorova, Anna Z. Wec, Darryl Sampey, Kartik Chandran, Nicole M. Josleyn, Stephen J. Streatfield, Jeffery W. Froude, Ognian Bohorov, Samantha E. Zak, Zachary A. Bornholdt, Russell R. Bakken, R. Mark Jones, Andrew S. Herbert, Brian J. Green, Larry Zeitlin, Ana I. Kuehne, Do Han Kim, Spencer W. Stonier, Kevin J. Whaley, Danielle E. Dorosky, Michael H. Pauly, John M. Dye, Jesus Velasco, Vidadi Yusibov, Konstantin Musiychuk
Publikováno v:
Proc Natl Acad Sci U S A
Antibody-based therapies are a promising treatment option for managing ebolavirus infections. Several Ebola virus (EBOV)-specific and, more recently, pan-ebolavirus antibody cocktails have been described. Here, we report the development and assessmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bf42afc446d92805ad31e97b88321f
https://doi.org/10.1073/pnas.1914985117
https://doi.org/10.1073/pnas.1914985117
Autor:
Kelsi, Swope, Josh, Morton, Gregory P, Pogue, Steve, Hume, Michael H, Pauly, John, Shepherd, Carrie A, Simpson, Barry, Bratcher, Kevin J, Whaley, Larry, Zeitlin, Keith R, Davis, Hugh, Haydon
Publikováno v:
Methods in enzymology. 660
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2dd51b13b1765289cec7315a4129cef7
https://pubmed.ncbi.nlm.nih.gov/34742392
https://pubmed.ncbi.nlm.nih.gov/34742392
Autor:
Samuel K. Lai, Bhawana Shrestha, Thomas R. Moench, Massoud Motamedi, Henry Pham, Michael H. Pauly, Josh Morton, Gracie Vargas, Kevin J. Whaley, Larry Zeitlin, Carrie A. Simpson, Alison Schaefer, Kelsi Swope, Kathleen L. Vincent, Yong Zhu, Miles B. Brennan, Barry Bratcher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Nearly half of all pregnancies in the United States are unintended due to millions of women avoiding available hormonal contraceptive methods as a result of real and/or perceived side effects associated with the use of exogenous hormones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e68710949be7983f8592853a85da6d
http://europepmc.org/articles/PMC8640842
http://europepmc.org/articles/PMC8640842
Autor:
Deborah J. Anderson, Emilie Mausser, Jeffrey Pudney, Gabriela Baldeon-Vaca, Miles B. Brennan, Kevin J. Whaley, Thomas R. Moench, Michael H. Pauly, James Doud, Larry Zeitlin, Joseph A. Politch, Ellena Nador, Jai G Marathe
Publikováno v:
EBioMedicine, Vol 69, Iss, Pp 103478-(2021)
EBioMedicine
EBioMedicine
Background Approximately 40% of human pregnancies are unintended, indicating a need for more acceptable effective contraception methods. New antibody production systems make it possible to manufacture reagent-grade human monoclonal antibodies (mAbs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972e8ecbe428dd36ac941ef8032e762d
http://www.sciencedirect.com/science/article/pii/S2352396421002711
http://www.sciencedirect.com/science/article/pii/S2352396421002711
Autor:
Simpson C, Pham H, Larry Zeitlin, Massoud Motamedi, Bhawana Shrestha, Gracie Vargas, Kathleen L. Vincent, Morton J, Brennan Mb, Yingjie Zhu, Sam Lai, Kevin J. Whaley, Michael H. Pauly, Alison Schaefer, Thomas R. Moench, Bratcher B, Swope K
Non-hormonal products for on-demand contraception are a global health technology gap, motivating us to pursue the use of sperm-binding monoclonal antibodies as a strategy to enable safe, effective, desirable, on-demand contraception. Here, using cGMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1d1c7c98fffbc4b80c8d5aeafc5080
https://doi.org/10.1101/2021.04.19.440503
https://doi.org/10.1101/2021.04.19.440503