Zobrazeno 1 - 10
of 14
pro vyhledávání: '"H. Patrick Macknight"'
Autor:
Curtis B. Read, Anika N. Ali, Daniel J. Stephenson, H. Patrick Macknight, Kenneth D. Maus, Chelsea L. Cockburn, Minjung Kim, Xiujie Xie, Jason A. Carlyon, Charles E. Chalfant
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTMany intracellular pathogens structurally disrupt the Golgi apparatus as an evolutionarily conserved promicrobial strategy. Yet, the host factors and signaling processes involved are often poorly understood, particularly for Anaplasma phagocy
Externí odkaz:
https://doaj.org/article/10e5f04be2dd4e119229141c954aa4ba
Autor:
Daniel J. Stephenson, H. Patrick MacKnight, L. Alexis Hoeferlin, Sonya L. Washington, Chelsea Sawyers, Kellie J. Archer, Jerome F. Strauss, III, Scott W. Walsh, Charles E. Chalfant
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 6, Pp 100377- (2023)
There are few early biomarkers to identify pregnancies at risk of preeclampsia (PE) and abnormal placental function. In this cross-sectional study, we utilized targeted ultra-performance liquid chromatography-ESI MS/MS and a linear regression model t
Externí odkaz:
https://doaj.org/article/522536cd3ef54007b913cd11e770819b
Autor:
Heather L. Caslin, Kasalina N. Kiwanuka, Tamara T. Haque, Marcela T. Taruselli, H. Patrick MacKnight, Anuya Paranjape, John J. Ryan
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mast cells are tissue resident, innate immune cells with heterogenous phenotypes tuned by cytokines and other microenvironmental stimuli. Playing a protective role in parasitic, bacterial, and viral infections, mast cells are also known for their rol
Externí odkaz:
https://doaj.org/article/072155e06a39426fa52e2ff558c0e5aa
Ceramide kinase (CERK) is the mammalian lipid kinase from which the bioactive sphingolipid, ceramide-1-phosphate (C1P), is derived. CERK has been implicated in several promalignant phenotypes with little known as to mechanistic underpinnings. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24eeb8a90499c5fe38d293a247c3de34
https://doi.org/10.1158/1541-7786.c.6545652
https://doi.org/10.1158/1541-7786.c.6545652
Publikováno v:
Biodivers Genomes
The Boelen’s Python (Simalia boeleni) is a python endemic to the mountains of New Guinea. We present the whole genome sequence of this species. Illumina sequencing was performed on a genetic sample from a single individual. The reads were assembled
Publikováno v:
Mol Cancer Res
Ceramide kinase (CERK) is the mammalian lipid kinase from which the bioactive sphingolipid, ceramide-1-phosphate (C1P), is derived. CERK has been implicated in several promalignant phenotypes with little known as to mechanistic underpinnings. In this
Autor:
Margaret A. Park, Charles E. Chalfant, Shaun C. Stevens, H. Patrick MacKnight, Keli K. Doe, Gina S. Nazario-Muñoz, James T. DeLigio
Publikováno v:
Mol Cancer Res
Triple negative breast cancer (TNBC) has an unusually low 5-year survival rate linked to higher metastatic rates. Our laboratory recently delineated a role for the alternative RNA splicing (AS) of cytoplasmic polyadenylation element binding protein 2
Autor:
Jeremy C. Allegood, Christopher L. Cardona, Charles E. Chalfant, Margaret A. Park, H. Patrick MacKnight, Daniel J. Stephenson, L. Alexis Hoeferlin
Publikováno v:
Analytical Methods. 11:1765-1776
Phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are highly prevalent phospholipids in mammalian membranes. There are currently no methods for detection of minute levels of these phospholipids or simultaneously with products of the utilizat
Autor:
H Patrick, MacKnight, Daniel J, Stephenson, L Alexis, Hoeferlin, Savannah D, Benusa, James T, DeLigio, Kenneth D, Maus, Anika N, Ali, Jennifer S, Wayne, Margaret A, Park, Edward H, Hinchcliffe, Rhoderick E, Brown, John J, Ryan, Robert F, Diegelmann, Charles E, Chalfant
Publikováno v:
Sci Signal
The sphingolipid ceramide-1-phosphate (C1P) directly binds to and activates group IVA cytosolic phospholipase A(2) (cPLA(2)α) to stimulate the production of eicosanoids. Because eicosanoids are important in wound healing, we examined the repair of s
Autor:
Anuya Paranjape, Tamara T. Haque, H. Patrick MacKnight, Heather L. Caslin, Marcela T. Taruselli, Kasalina N. Kiwanuka, John J. Ryan
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Mast cells are tissue resident, innate immune cells with heterogenous phenotypes tuned by cytokines and other microenvironmental stimuli. Playing a protective role in parasitic, bacterial, and viral infections, mast cells are also known for their rol