Zobrazeno 1 - 10
of 58
pro vyhledávání: '"H. P. Simons"'
Publikováno v:
Children, Vol 11, Iss 9, p 1102 (2024)
Similar to other populations, care of neonates strongly relies on robust guidance on neonatal pharmacotherapy, covering an age-appropriate drug formulation, an individualized dose, and information on its efficacy and safety for a specific indication
Externí odkaz:
https://doaj.org/article/17ec53265cfa4338acf3f4b4dbcbd1bd
Autor:
Jarinda A. Poppe, Robert B. Flint, Anne Smits, Sten P. Willemsen, Kelly K. Storm, Debbie H. Nuytemans, Wes Onland, Marten J. Poley, Willem P. de Boode, Katherine Carkeek, Vincent Cassart, Luc Cornette, Peter H. Dijk, Marieke A. C. Hemels, Isabelle Hermans, Matthias C. Hütten, Dorottya Kelen, Ellen H. M. de Kort, André A. Kroon, Julie Lefevere, Katleen Plaskie, Breanne Stewart, Michiel Voeten, Mirjam M. van Weissenbruch, Olivia Williams, Inge A. Zonnenberg, Thierry Lacaze-Masmonteil, Arjan B.te Pas, Irwin K. M. Reiss, Anton H. van Kaam, Karel Allegaert, G. Jeroen Hutten, Sinno H. P. Simons
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Apnoea of prematurity (AOP) is one of the most common diagnoses among preterm infants. AOP often leads to hypoxemia and bradycardia which are associated with an increased risk of death or disability. In addition to caffeine therap
Externí odkaz:
https://doaj.org/article/1beb5ecbe5d64793b43c02fe04d5f72b
Autor:
Zakile A. Mfumbilwa, Janneke A. Wilschut, Martijn J. H. G. Simons, Bram Ramaekers, Manuela Joore, Valesca Retèl, Christine M. Cramer-van der Welle, Franz M. N. H. Schramel, Ewoudt M. W. van de Garde, Veerle M. H. Coupé
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Recent discoveries in molecular diagnostics and drug treatments have improved the treatment of patients with advanced (inoperable) non-squamous non-small cell lung cancer (NSCLC) from solely platinum-based chemotherapy to more personalized t
Externí odkaz:
https://doaj.org/article/fa5c1807869049718099709fd7398401
Autor:
Serife Kurul, H. Rob Taal, Robert B. Flint, Jan Mazela, Irwin K. M. Reiss, Karel Allegaert, Sinno H. P. Simons
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Late onset sepsis is a leading cause of death and morbidity in preterm infants. Despite optimal antibiotic treatment, sepsis related mortality and morbidity is still high. Pentoxifylline (PTX) is a methylxanthine with promising im
Externí odkaz:
https://doaj.org/article/04f096fd61b94ec28099d40747b9f4db
Autor:
Michiel van de Ven, Martijn J. H. G. Simons, Hendrik Koffijberg, Manuela A. Joore, Maarten J. IJzerman, Valesca P. Retèl, Wim H. van Harten
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background In oncology, Whole Genome Sequencing (WGS) is not yet widely implemented due to uncertainties such as the required infrastructure and expertise, costs and reimbursements, and unknown pan-cancer clinical utility. Therefore, this st
Externí odkaz:
https://doaj.org/article/d922fbd1e74a4e068c3f975538235bae
Autor:
Şerife Kurul, Sinno H. P. Simons, Christian R. B. Ramakers, Yolanda B. De Rijke, René F. Kornelisse, Irwin K. M. Reiss, H. Rob Taal
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-10 (2021)
Abstract Background Sepsis is a major health issue in preterm infants. Biomarkers are used to diagnose and monitor patients with sepsis, but C-reactive protein (CRP) is proven not predictive at onset of late onset neonatal sepsis (LONS) diagnosis. Th
Externí odkaz:
https://doaj.org/article/7a38c7a6f7224c9b82e5566ecee17450
Autor:
Şerife Kurul, BSc, Sinno H. P. Simons, MD, PhD, Christian R. B. Ramakers, PhD, Yolanda B. De Rijke, PhD, René F. Kornelisse, MD, PhD, André A. Kroon, MD, PhD, Irwin K. M. Reiss, MD, PhD, H. Rob Taal, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 12, p e0585 (2021)
BACKGROUND:. Late-onset neonatal sepsis is a major complication in preterm neonates. Early identification of the type of infection could help to improve therapy and outcome depending on the suspected microorganism by tailoring antibiotic treatment to
Externí odkaz:
https://doaj.org/article/ac7f412ba39f4d85ade7dc75bf4f0acc
Autor:
Pomme I. H. G. Simons, Olivier Valkenburg, Judith A. P. Bons, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 4, Iss 3, Pp n/a-n/a (2021)
Abstract Objective A recent Mendelian randomization study has suggested a causal role for sex hormone‐binding globulin (SHBG), total testosterone and free testosterone in the pathogenesis of polycystic ovary syndrome (PCOS). The aim of this study w
Externí odkaz:
https://doaj.org/article/9bb10630ed53402584ed791adef4b12e
Autor:
Liron Borenstein-Levin, Jarinda A. Poppe, Willem van Weteringen, H. Rob Taal, Ori Hochwald, Amir Kugelman, Irwin K. M. Reiss, Sinno H. P. Simons
Publikováno v:
Pediatric Research, 93(4), 932-937. Lippincott Williams & Wilkins
Background: An oxygen saturation (SpO2) histogram classification system has been shown to enable quantification of SpO2 instability into five types, based on histogram distribution and time spent at SpO2 ≤ 80%. We aimed to investigate this classifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2f9c680843c8927f8b3f8ee4ef22ab
https://pure.eur.nl/en/publications/fd925ccc-a091-4bdf-b600-d107ead032e2
https://pure.eur.nl/en/publications/fd925ccc-a091-4bdf-b600-d107ead032e2
Autor:
Jeroen V. Koomen, Jasper Stevens, Margje H. Monster-Simons, Hiddo J. L. Heerspink, Peter G. M. Mol
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Aims: Cardiovascular outcome trials with anti-diabetic drugs suggest that additional cardiovascular benefit can be achieved independent of improving glycaemic control. Nonetheless, dose selection of anti-diabetic drugs is typically based solely on gl
Externí odkaz:
https://doaj.org/article/5edc851acb95406ebbea9ed24af0c1ac