Zobrazeno 1 - 10
of 463
pro vyhledávání: '"H. Oakley"'
Autor:
Harshvardhan Gazula, Henry FJ Tregidgo, Benjamin Billot, Yael Balbastre, Jonathan Williams-Ramirez, Rogeny Herisse, Lucas J Deden-Binder, Adria Casamitjana, Erica J Melief, Caitlin S Latimer, Mitchell D Kilgore, Mark Montine, Eleanor Robinson, Emily Blackburn, Michael S Marshall, Theresa R Connors, Derek H Oakley, Matthew P Frosch, Sean I Young, Koen Van Leemput, Adrian V Dalca, Bruce Fischl, Christine L MacDonald, C Dirk Keene, Bradley T Hyman, Juan E Iglesias
Publikováno v:
eLife, Vol 12 (2024)
We present open-source tools for three-dimensional (3D) analysis of photographs of dissected slices of human brains, which are routinely acquired in brain banks but seldom used for quantitative analysis. Our tools can: (1) 3D reconstruct a volume fro
Externí odkaz:
https://doaj.org/article/bee5031ed3ac4569bd31db0c5630fc96
Publikováno v:
Neurobiology of Stress, Vol 28, Iss , Pp 100589- (2024)
Many stress-related neuropsychiatric disorders display pronounced sex differences in their frequency and clinical symptoms. Glucocorticoids are primary stress hormones that have been implicated in the development of these disorders but whether they c
Externí odkaz:
https://doaj.org/article/e7dd9677251141698fad4c81d5073831
Autor:
John H. Oakley, John Oakley
Painted vases are the richest and most complex images that remain from ancient Greece. Over the past decades, a great deal has been written on ancient art that portrays myths and rituals. Less has been written on scenes of daily life, and what has be
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Bcl-2 is an anti-apoptotic protein that promotes cell survival and resistance to cell death. Predictably, Bcl-2 as well as other anti-apoptotic Bcl-2 family members have been found to be overexpressed in a variety of human cancers. Approache
Externí odkaz:
https://doaj.org/article/1d6d6b6107bc4e43abb337ce19cbc7e6
Autor:
Jonathan Vogelgsang, Shu Dan, Anna P. Lally, Michael Chatigny, Sangeetha Vempati, Joshua Abston, Peter T. Durning, Derek H. Oakley, Thomas H. McCoy, Torsten Klengel, Sabina Berretta
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract Introduction Transdiagnostic dimensional phenotypes are essential to investigate the relationship between continuous symptom dimensions and pathological changes. This is a fundamental challenge to post‐mortem work, as assessments of phenot
Externí odkaz:
https://doaj.org/article/412cd21b8c414ac0b15de2a1f4dde282
Autor:
Pia Kivisäkk, Becky C. Carlyle, Thadryan Sweeney, Bianca A. Trombetta, Kathryn LaCasse, Leena El-Mufti, Idil Tuncali, Lori B. Chibnik, Sudeshna Das, Clemens R. Scherzer, Keith A. Johnson, Bradford C. Dickerson, Teresa Gomez-Isla, Deborah Blacker, Derek H. Oakley, Matthew P. Frosch, Bradley T. Hyman, Anahit Aghvanyan, Pradeepthi Bathala, Christopher Campbell, George Sigal, Martin Stengelin, Steven E. Arnold
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe last few years have seen major advances in blood biomarkers for Alzheimer's Disease (AD) with the development of ultrasensitive immunoassays, promising to transform how we diagnose, prognose, and track progression of neurodegenerative d
Externí odkaz:
https://doaj.org/article/6404f04c0c8f4fdea79ffcc9b0fb11c5
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/8b8df1ea8f9b42538ad4cb777158ad4b
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Cubomedusae, or box jellyfish, have a complex visual system comprising 24 eyes of four types. Like other cnidarians, their photoreceptor cells are ciliary in morphology, and a range of different techniques together show that at least two of the eye t
Externí odkaz:
https://doaj.org/article/6b82f0f85f174b069d878b8286c28005
Autor:
Pablo Ruiz, Paul Gabarre, Camille Chenevier-Gobeaux, Hélène François, Mathieu Kerneis, John A. Cidlowski, Robert H. Oakley, Guillaume Lefèvre, Mathieu Boissan
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundTakotsubo syndrome is an acute cardiac condition usually involving abnormal regional left ventricular wall motion and impaired left ventricular contractility. It is due mainly to hyper-stimulation of the sympathetic nerve system, inducing a
Externí odkaz:
https://doaj.org/article/431cd91039864eb4b51952ae1357c5a7
Autor:
Abdullah Al Bashit, Prakash Nepal, Theresa Connors, Derek H. Oakley, Bradley T. Hyman, Lin Yang, Lee Makowski
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Alzheimer’s disease (AD) is a neurodegenerative disorder defined by the progressive formation and spread of fibrillar aggregates of Aβ peptide and tau protein. Polymorphic forms of these aggregates may contribute to disease in varying ways since d
Externí odkaz:
https://doaj.org/article/9dfac35355734131b590be03d725eab7