Výsledky vyhledávání - "H. O'brodovich"

Fetal lung epithelial cells contain two populations of amiloride-sensitive Na+ channels

Autor: E. J. Cragoe, M.L. Bauer, Sadis Matalon, H. O'Brodovich, Dale J. Benos, T. R. Kleyman, C. Lin

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 264:L357-L364

Active Na+ transport by the alveolar epithelium plays a major role in reabsorption of the fetal lung fluid after birth. We characterized the biochemical and physiological characteristics of Na+ conductive pathways in distal fetal lung epithelial (FLE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36176d12d414ad4ee33c61416600018f
https://doi.org/10.1152/ajplung.1993.264.4.l357

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Career development and compensation: strategies for physicians in academic health science centers. A perspective from a Canadian academic health science center

Autor: H, O'Brodovich

Publikováno v: The Journal of pediatrics. 139(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::831944bac16a27ca154f173aea7e117a
https://pubmed.ncbi.nlm.nih.gov/11487737

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Expression of alpha-, beta-, and gamma-hENaC mRNA in the human nasal, bronchial, and distal lung epithelium

Autor: O M, Pitkänen, D, Smith, H, O'Brodovich, G, Otulakowski

Publikováno v: American journal of respiratory and critical care medicine. 163(1)

The amount of fluid covering the epithelium of the airways and alveolar space is modulated by active transport of Na+ from the lumen through the apical membrane Na+ permeant ion channels towards the interstitial space. We have measured the subunit ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a96451d71b998e644999f46df6ceecf
https://pubmed.ncbi.nlm.nih.gov/11208656

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Regulation of an amiloride-sensitive Na+-permeable channel by a beta2-adrenergic agonist, cytosolic Ca2+ and Cl- in fetal rat alveolar epithelium

Autor: Y, Marunaka, N, Niisato, H, O'Brodovich, D C, Eaton

Publikováno v: The Journal of physiology. 515

1. In cell-attached patches formed on the apical membrane of fetal alveolar epithelium, terbutaline (a specific beta2-adrenergic agonist) increased the open probability (Po) of an amiloride-sensitive Na+-permeable non-selective cation (NSC) channel (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b473acc95341d7313f88a1cf697bfd99
https://pubmed.ncbi.nlm.nih.gov/10066896

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HSC clinical trials controversy continues. Hospital for Sick Children

Autor: M, Buchwald, H, O'Brodovich

Publikováno v: Nature medicine. 5(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0539cd7ecaed5fbd5afa36540380ff61
https://pubmed.ncbi.nlm.nih.gov/9883822

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Covalent heparin cofactor II-heparin and heparin cofactor II-dermatan sulfate complexes. Characterization of novel anticoagulants

Autor: P, Monagle, L, Berry, H, O'Brodovich, M, Andrew, A, Chan

Publikováno v: The Journal of biological chemistry. 273(50)

Heparin cofactor II is a naturally occurring anticoagulant that acts by specifically inhibiting thrombin and is facilitated by the binding of glycosaminoglycans such as heparin and dermatan sulfate. In vivo, heparin cofactor II-glycosaminoglycan comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1dea5621f60ee15bc9adaa35477e7ed7
https://pubmed.ncbi.nlm.nih.gov/9837939

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Covalent antithrombin-heparin complexes with high anticoagulant activity. Intravenous, subcutaneous, and intratracheal administration

Autor: A, Chan, L, Berry, H, O'Brodovich, P, Klement, L, Mitchell, B, Baranowski, P, Monagle, M, Andrew

Publikováno v: The Journal of biological chemistry. 272(35)

Although heparin has been used clinically for prophylaxis and treatment of thrombosis, it has suffered from problems such as short duration within compartments in vivo that require long term anticoagulation. A covalent antithrombin-heparin complex ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6703594ef1d0d1b7c022d7704f9fe5d
https://pubmed.ncbi.nlm.nih.gov/9268354

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Lung fluid restriction affects growth but not airway branching of embryonic rat lung

Autor: P, Souza, H, O'Brodovich, M, Post

Publikováno v: The International journal of developmental biology. 39(4)

During the later stages of fetal life lung growth and development is dependent upon a variety of factors, including a normal amount of liquid within the lung's lumen. To investigate whether embryonic lung epithelium secretes fluid and whether lung li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54f6e42312bdb3d15d8111f2b535314c
https://pubmed.ncbi.nlm.nih.gov/8619961

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A concurrent cefuroxime use evaluation in pediatric patients

Autor: F C, Obilio, C, Petrou, M H, O'Brodovich

Publikováno v: The Canadian journal of hospital pharmacy. 46(5)

A concurrent evaluation of cefuroxime use in pediatric patients is described. From March 5, 1991 to May 15, 1991, the use of cefuroxime in pediatric patients was evaluated. The pediatric liaison pharmacist collected clinical information about each pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08c5e7292399f74d6da550c5ee8eaee0
https://pubmed.ncbi.nlm.nih.gov/10130374

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