Zobrazeno 1 - 10
of 136
pro vyhledávání: '"H. Nugent"'
Publikováno v:
BJA Open, Vol 6, Iss , Pp 100153- (2023)
Externí odkaz:
https://doaj.org/article/c701d126573f4d03813a971e83a230aa
Publikováno v:
BJA Open, Vol 6, Iss , Pp 100167- (2023)
Externí odkaz:
https://doaj.org/article/c2c7cad4498d4680869bde6da2d20d45
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 49, Iss 1, Pp 709-716 (2021)
Acute respiratory distress syndrome (ARDS) features pulmonary dysfunction capable of causing life-threatening hypoxaemia. Ventilation and hyperoxic therapies force oxygen through dysfunctional alveoli but risk exacerbating damage. Ox66™ is an inges
Externí odkaz:
https://doaj.org/article/dc4cb4968003468eb6d64cc245010b0f
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 48, Iss 1, Pp 1079-1088 (2020)
Medical support for traumatic haemorrhage is lacking for far-forward combat units. VIR-HBOC (haemoglobin-based oxygen carrier) is a novel biological therapeutic under development as a field-stable resuscitation fluid. HBOCs have a long history of com
Externí odkaz:
https://doaj.org/article/508b27af921a48daa076080fed69307e
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 47, Iss 1, Pp 95-103 (2019)
Hypoxia drives sickle cell disease (SCD) by inducing sickle cell haemoglobin to polymerize and deform red blood cells (RBC) into the sickle shape. A novel carboxyhaemoglobin-based oxygen carrier (PEG-COHb; PP-007) promotes unsickling in vitro by reli
Externí odkaz:
https://doaj.org/article/f6eb8f10d809490c970dc0328a9c532a
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology. 51:33-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a701de17d6564d72f20fe7e40ea9304d
https://doi.org/10.1080/21691401.2022.2164584
https://doi.org/10.1080/21691401.2022.2164584
Autor:
Kellie J. Archer, William H. Nugent, Marwah Al Dulaimi, Scott W. Walsh, Sonya L. Washington, Jerome F. Strauss
Publikováno v:
Reprod Sci
DNA methylation is an epigenetic mechanism controlling gene expression, and reduced methylation is associated with increased gene expression. We hypothesized that IL-17 cytokines are regulated by DNA methylation, are elevated in the circulation of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45ed48a109e0e755930978a14aca8d8
https://doi.org/10.1007/s43032-021-00605-3
https://doi.org/10.1007/s43032-021-00605-3
Autor:
T. Crocker-Buque, S. Williams, A. R. Brentnall, R. Gabe, S. Duffy, J. R. Prowle, C. Orkin, H. Kunst, T. Cutino-Moguel, D. Zenner, B. Bloom, M. Melzer, S. de Freitas, M. Darmalingam, K. McCafferty, V. Kapil, P. Pfeffer, J. Martin, Y. Gourtsoyannis, S. Chandran, A. Dhariwal, R. Rachman, I. Milligan, D. Mabayoje, E. Adobah, J. Falconer, H. Nugent, M. Yaqoob, D. Collier, R. Pearse, M. Caulfield, S. Tiberi, null on behalf of the Barts Health and Queen Mary
Publikováno v:
The International Journal of Tuberculosis and Lung Disease. 25:358-366
BACKGROUND: Barts Health National Health Service Trust (BHNHST) serves a diverse population of 2.5 million people in London, UK. We undertook a health services assessment of factors used to evaluate the risk of severe acute respiratory coronavirus 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67123c6a602c2cc7bf0dd55d7fac72bb
https://doi.org/10.5588/ijtld.20.0926
https://doi.org/10.5588/ijtld.20.0926
Publikováno v:
Journal of Applied Physiology. 128:1579-1586
Hemolytic anemia (HA) is reduced blood oxygen-carrying capacity resulting from the depletion of red blood cells. Treatment for severe cases involves transfusion to improve oxygen delivery (Do2), which carries risk. In humans, a total hemoglobin (tHb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdc4d891e24bddd2677f2cc463c0bce
https://doi.org/10.1152/japplphysiol.00767.2019
https://doi.org/10.1152/japplphysiol.00767.2019
Autor:
Forest R. Sheppard, Abe Abuchowski, Daniel N. Darlington, Ronald Jubin, Ramon F. Cestero, Bjorn K. Song, William H. Nugent, Michael A. Dubick
Publikováno v:
Shock. 53:493-502
BACKGROUND Hemorrhage is the leading cause of preventable, traumatic death. Currently, prehospital resuscitation fluids provide preload but not oxygen-carrying capacity-a critical blood function that mitigates microvascular ischemia and tissue hypoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97b5b70c5b3d4da01c3161d9afd0edc
https://doi.org/10.1097/shk.0000000000001370
https://doi.org/10.1097/shk.0000000000001370