Zobrazeno 1 - 10
of 279
pro vyhledávání: '"H. Nicolay"'
Autor:
Athanasios Kafkaletos, Michael Mix, Ilias Sachpazidis, Montserrat Carles, Alexander Rühle, Juri Ruf, Anca L. Grosu, Nils H. Nicolay, Dimos Baltas
Publikováno v:
EJNMMI Physics, Vol 11, Iss 1, Pp 1-20 (2024)
Abstract Background The purpose of this study was to evaluate how a retrospective correction of the partial volume effect (PVE) in [18F]fluoromisonidazole (FMISO) PET imaging, affects the hypoxia discoverability within a gross tumour volume (GTV). Th
Externí odkaz:
https://doaj.org/article/9ee0dcb996904ccfa6fb5b162e2f27fd
Autor:
Helena C. Bitz, Ilias Sachpazidis, Jiadai Zou, Daniel Schnell, Dimos Baltas, Anca-Ligia Grosu, Nils H. Nicolay, Alexander Rühle
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Purpose The number of older adults with head and neck squamous cell carcinoma (HNSCC) is continuously increasing. Older HNSCC patients may be more vulnerable to radiotherapy-related toxicities, so that extrapolation of available normal tissu
Externí odkaz:
https://doaj.org/article/6517e16aef0d4fb1a37111fb69b1490f
Autor:
Eleni Gkika, Elke Firat, Sonja Adebahr, Erika Graf, Ilinca Popp, Gianluca Radicioni, Simon S. Lo, Ursula Nestle, Nils H. Nicolay, Gabriele Niedermann, Dan G. Duda, Anca-L. Grosu
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract We performed a prospective study of circulating immune cell changes after stereotactic body radiotherapy (SBRT) in 50 early-stage NSCLC patients. We found no significant increase in CD8+ cytotoxic T lymphocytes at first follow-up (the primar
Externí odkaz:
https://doaj.org/article/537504b77a584db7a48979724411a17a
Autor:
Georg W. Wurschi, Alexander Rühle, Justus Domschikowski, Maike Trommer, Simone Ferdinandus, Jan-Niklas Becker, Simon Boeke, Mathias Sonnhoff, Christoph A. Fink, Lukas Käsmann, Melanie Schneider, Elodie Bockelmann, David Krug, Nils H. Nicolay, Alexander Fabian, Klaus Pietschmann
Publikováno v:
Cancers, Vol 16, Iss 7, p 1281 (2024)
Total neoadjuvant therapy (TNT) is an evolving treatment schedule for locally advanced rectal cancer (LARC), allowing for organ preservation in a relevant number of patients in the case of complete response. Patients who undergo this so-called “wat
Externí odkaz:
https://doaj.org/article/9d8f1b7241bf434188a99eb3cdce0345
Autor:
Alexander Rühle, Jovan Todorovic, Simon S. K. Spohn, Eleni Gkika, Christoph Becker, Andreas Knopf, Constantinos Zamboglou, Tanja Sprave, Martin Werner, Anca-Ligia Grosu, Gian Kayser, Nils H. Nicolay
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background and purpose Tumor-infiltrating lymphocytes (TILs) are associated with locoregional control (LRC) in head-and-neck squamous cell carcinoma (HNSCC) patients undergoing (chemo)radiotherapy. As immunosenescence results in reduced immu
Externí odkaz:
https://doaj.org/article/1e1becab28f1449e921cca6d2bc72d54
Autor:
Alexander Rühle, Verlaine Ange Nya Yompang, Simon K. B. Spohn, Raluca Stoian, Constantinos Zamboglou, Eleni Gkika, Anca-Ligia Grosu, Nils H. Nicolay, Tanja Sprave
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Background Accompanied by the demographic change, the number of octogenarian cancer patients with bone metastases will increase in the future. Palliative radiotherapy constitutes an effective analgesic treatment; however, as pain perception
Externí odkaz:
https://doaj.org/article/43cb23480cec47b88666962769d1a0c6
Autor:
Seong Jeong, Soniya Poudyal, Sabine Klagges, Thomas Kuhnt, Kirsten Papsdorf, Peter Hambsch, Johannes Wach, Erdem Güresir, Franziska Nägler, Alexander Rühle, Nils H. Nicolay, Clemens Seidel
Publikováno v:
Cancers, Vol 15, Iss 19, p 4845 (2023)
Background: Brain metastases (BM) cause relevant morbidity and mortality in cancer patients. The presence of cerebrovascular diseases can alter the tumor microenvironment, cellular proliferation and treatment resistance. However, it is largely unknow
Externí odkaz:
https://doaj.org/article/d8f0ed076a974da18e39b80dc3366ac2
Autor:
Jule Wolf, Steffen Kurz, Thomas Rothe, Marco Serpa, Jutta Scholber, Thalia Erbes, Eleni Gkika, Dimos Baltas, Vivek Verma, David Krug, Ingolf Juhasz-Böss, Anca-Ligia Grosu, Nils H. Nicolay, Tanja Sprave
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Radiotherapy using the deep inspiration breath-hold (DIBH) technique compared with free breathing (FB) can achieve substantial reduction of heart and lung doses in left-sided breast cancer cases. The anatomical organ movement in d
Externí odkaz:
https://doaj.org/article/cd2fc0dd15cb4b09b125d49333682b00
Autor:
Alexander Rühle, Anca-L. Grosu, Nicole Wiedenmann, Juri Ruf, Birgit Bieber, Raluca Stoian, Andreas R. Thomsen, Eleni Gkika, Peter Vaupel, Dimos Baltas, Wolfgang A. Weber, Michael Mix, Nils H. Nicolay
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 33, Iss , Pp 120-127 (2022)
Background: Tumor hypoxia worsens the prognosis of head-and-neck squamous cell carcinoma (HNSCC) patients, and plasma hypoxia markers may be used as biomarkers for radiotherapy personalization. We therefore investigated the role of the hypoxia-associ
Externí odkaz:
https://doaj.org/article/609bfa9ad90f490aa4546f8f6f71895f
Autor:
S. K. B. Spohn, S. Adebahr, M. Huber, C. Jenkner, R. Wiehle, B. Nagavci, C. Schmucker, E. G. Carl, R. C. Chen, W. A. Weber, M. Mix, A. Rühle, T. Sprave, N. H. Nicolay, C. Gratzke, M. Benndorf, T. Wiegel, J. Weis, D. Baltas, A. L. Grosu, C. Zamboglou
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Objective Failure rate in randomized controlled trials (RCTs) is > 50%, includes safety-problems, underpowered statistics, lack of efficacy, lack of funding or insufficient patient recruitment and is even more pronounced in oncology trials.
Externí odkaz:
https://doaj.org/article/4df0f24edbe84ea191fc61feb426fbb3