Zobrazeno 1 - 10
of 68
pro vyhledávání: '"H. Murli"'
Autor:
Yong Xu, Marie McKeon, Ajit K. Thakur, Timothy E. Lawlor, H. Murli, Daniel J. Roberts, Leon F. Stankowski, Hepei Chen
Publikováno v:
Environmental and Molecular Mutagenesis. 52:738-747
As part of the Stage III Pig-a multilaboratory validation trial, we examined the induction of CD59-negative reticulocytes and total red blood cells (RETCD59− and RBCCD59−, respectively) in male Sprague Dawley® rats treated with 4-nitroquinoline-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc1649efe5a96b7158eee02e06bfb6f
https://doi.org/10.1002/em.20692
https://doi.org/10.1002/em.20692
Publikováno v:
Inhalation Toxicology. 13:1079-1091
Genotoxicity evaluations have been proposed as regulatory requirements for establishing German MAK values for inhaled fibrous dusts. The objective of this in vitro assay was to assess the potential for para-aramid (p-aramid) respirable-sized, fiber-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0e30ffc75543112c897c238e41cf65
https://doi.org/10.1080/08958370152647627
https://doi.org/10.1080/08958370152647627
Publikováno v:
Food and Chemical Toxicology. 38:971-976
ARASCO and DHASCO oils are microbially-derived triglycerides rich in arachidonic (20:4n-6) and docosahexaenoic (22:6n-3) acids, respectively. Both oils were tested for mutagenic activity in three different in vitro mutagenesis assays. All assays were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df7846d6158d052c7e18327c575579e
https://doi.org/10.1016/s0278-6915(00)00085-5
https://doi.org/10.1016/s0278-6915(00)00085-5
Autor:
Lutz Müller, Ronald D. Snyder, Elmar Gocke, Colin F. Chignell, Susanne Brendler-Schwaab, Peggy J. Guzzie, Noriho Tanaka, H. Murli, Steven J. Bulera, Abby Jacobs, Leigh M. Henderson
Publikováno v:
Environmental and Molecular Mutagenesis. 35:173-184
Recent toxicological observations have caused concern regarding the need to test, for example, pharmaceuticals and cosmetic products for photochemical genotoxicity. The objective of this report is to give assistance on how to adapt existing test meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfa8ae0d91ae35e00baa7f90880200b8
https://doi.org/10.1002/(sici)1098-2280(2000)35:3<173::aid-em4>3.0.co
https://doi.org/10.1002/(sici)1098-2280(2000)35:3<173::aid-em4>3.0.co
Autor:
K.P Putnam, B.Reed Bombick, Walter T. Morgan, J.T Avalos, D.W Bombick, H Murli, David J. Doolittle
Publikováno v:
Food and Chemical Toxicology. 36:183-190
The genotoxic and cytotoxic potential of mainstream cigarette smoke condensate (CSC) from a new cigarette that primarily heats tobacco (TOB-HT) was compared with that of CSC from a Kentucky reference low “tar” cigarette (1R4F) representative of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26251381acea0eff94b636908460109f
https://doi.org/10.1016/s0278-6915(97)00107-5
https://doi.org/10.1016/s0278-6915(97)00107-5
Autor:
Leon F. Stankowski, Richard A. Spellman, M. Chan, Ajit K. Thakur, D. J. Roberts, H. Chen, G. L. DeVito, H. Murli, Kelley E. Sanok, P. Yurt
Publikováno v:
Environmental and molecular mutagenesis. 53(4)
A flow cytometric procedure for determining mitotic index (MI) as part of the metaphase chromosome aberrations assay, developed and utilized routinely at Pfizer as part of their standard assay design, has been adopted successfully by Covance laborato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ac22158264a2883ffd9195cd0cdd76
https://pubmed.ncbi.nlm.nih.gov/22351437
https://pubmed.ncbi.nlm.nih.gov/22351437
Publikováno v:
Toxicological Sciences. 18:557-569
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9fc4b9fd08c4b4d4ef1043123874ba
https://doi.org/10.1093/toxsci/18.4.557
https://doi.org/10.1093/toxsci/18.4.557
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 44(11)
Salacia oblonga has been used for thousands of years in Ayurvedic medicine for the oral treatment of diabetes. The root extract has been shown to inhibit the activity of intestinal alpha-glucosidases, therefore S. oblonga holds potential as a natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa1fad73551d8541f143276797e482e
https://pubmed.ncbi.nlm.nih.gov/16901601
https://pubmed.ncbi.nlm.nih.gov/16901601
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 42(12)
Aristolochic acid (AA), the active compound found in Aristolochia extracts, has been used as a traditional medicine. However, products containing AA were withdrawn from the market in the early 1980s because AA was found to be a potent carcinogen. Som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f57c36c79057943eabd2284b6ca7bc6
https://pubmed.ncbi.nlm.nih.gov/15500939
https://pubmed.ncbi.nlm.nih.gov/15500939
Autor:
Colin Riach, Dawn Innes, H. Murli, Keith Bley, Greg Erexson, Frances Stevenson, Sanjay Chanda
Publikováno v:
Mutation research. 557(1)
Both positive and negative effects have been found in classical genetic toxicology assays with capsaicin. However, the capsaicin tested in most studies has been derived from pepper plant extracts, which is likely to display varying degrees of purity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81acd3b5f601c97a93d54d1217c0c96e
https://pubmed.ncbi.nlm.nih.gov/14706521
https://pubmed.ncbi.nlm.nih.gov/14706521