Výsledky vyhledávání - "H. Moha Ou Maati"

Role of the kcnk2 ion channel in zebrafish heart regeneration

Autor: L. Rolland, A. Faucherre, Nathalie Nasr, Chris Jopling, H. Moha Ou Maati

Publikováno v: Archives of Cardiovascular Diseases Supplements. 12:224

Introduction Myocardial infarction leads to a loss of cardiac tissue, which is then replaced by fibrosis. Following this loss in adult mammals, pathological hypertrophy takes place and leads to heart failure. Zebrafish are able to regenerate their he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fca3e304ae9f67d339b56b49f4961fba
https://doi.org/10.1016/j.acvdsp.2020.03.061

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In vitroandin vivoregulation of synaptogenesis by the novel antidepressant spadin

Autor: Sébastien Moreno, Jean Mazella, A Khayachi, Marc Borsotto, Stéphane Martin, H. Moha Ou Maati, Morgane Roulot, Christelle Devader, J. Veyssiere, Catherine Heurteaux

Publikováno v: British Journal of Pharmacology. 172:2604-2617

Background and Purpose We have described a novel antidepressant peptide, spadin, that acts by blocking the TWIK-related-potassium channel, type 1 (TREK-1). Here, we examined possible mechanisms of action of spadin at both molecular and cellular level

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::24b08eba19f63717169ff7371ecc50a9
https://doi.org/10.1111/bph.13083

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Targeting two-pore domain K+channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept

Autor: Jean Mazella, Marc Borsotto, H. Moha Ou Maati, Catherine Heurteaux, Christelle Devader, J. Veyssiere

Publikováno v: British Journal of Pharmacology. 172:771-784

Depression is a disease that is particularly frequent, affecting up to 20% of the population in Western countries. The origins of this pathology involve multiple genes as well as environmental and developmental factors leading to a disorder that rema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61f7a5258d9a3e45d03c1e049cca1057
https://doi.org/10.1111/bph.12953

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NeuroAiD: Properties for Neuroprotection and Neurorepair

Autor: Hervé Quintard, J. Veyssiere, H. Moha Ou Maati, C. Gandin, B. Onteniente, Catherine Heurteaux, M Lazdunski, Marc Borsotto, Catherine Widmann

Publikováno v: Cerebrovascular Diseases. 35:1-7

Background: Treatments for stroke and other brain injuries are limited. NeuroAiD has been shown to be beneficial in clinical studies. We reviewed the pharmacological effects of NeuroAiD on the normal and ischemic brain and neurons. Methods: In vivo a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708f58f61e4c8a980eeab6588fe176d3
https://doi.org/10.1159/000346228

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Relative contribution of SKCa and TREK1 channels in purinergic and nitrergic neuromuscular transmission in the rat colon

Autor: M. Martínez-Cutillas, Víctor Gil, D. Gallego, Marcel Jiménez, Catherine Heurteaux, Marc Borsotto, Rémi Peyronnet, H. Moha Ou Maati

Publikováno v: AJP-Gastrointestinal and Liver Physiology
AJP-Gastrointestinal and Liver Physiology, American Physiological Society, 2012, 303 (3), pp.G412-23. ⟨10.1152/ajpgi.00040.2012⟩

Purinergic and nitrergic neurotransmission predominantly mediate inhibitory neuromuscular transmission in the rat colon. We studied the sensitivity of both purinergic and nitrergic pathways to spadin, a TWIK-related potassium channel 1 (TREK1) inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1781a3cf3a1e1d76086ebb9ea8d412
https://doi.org/10.1152/ajpgi.00040.2012

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Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation: a key role for IKs

Autor: Patrick Bois, Olivier Stucker, Elisabeth Laemmel, Jean François Faivre, Stephen G. Dilly, Stephanie Guilbot, M Le Grand, Catherine Pons-Himbert, Joffrey Ducroq, H Moha ou Maati

Publikováno v: British Journal of Pharmacology. 159:93-101

Introduction: Doxorubicin, an anthracycline widely used in the treatment of a broad range of tumours, causes acute QT prolongation. Dexrazoxane has been shown to prevent the QT prolongation induced by another anthracycline, epirubicin, but has not ye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3459a0d9eb94f3dc4a5baf5946a52acd
https://doi.org/10.1111/j.1476-5381.2009.00371.x

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The role of mechanosensitive ion channels during zebrafish heart development and regeneration

Autor: I. El Rhoddani, H. Moha Ou Maati, Nathalie Nasr, Chris Jopling

Publikováno v: Archives of Cardiovascular Diseases Supplements. 9:166

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52ce8c9348cc8dbf736fd57096809049
https://doi.org/10.1016/s1878-6480(17)30413-5

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In vitro and in vivo regulation of synaptogenesis by the novel antidepressant spadin

Autor: C, Devader, A, Khayachi, J, Veyssière, H, Moha Ou Maati, M, Roulot, S, Moreno, M, Borsotto, S, Martin, C, Heurteaux, J, Mazella

Publikováno v: British journal of pharmacology. 172(10)

We have described a novel antidepressant peptide, spadin, that acts by blocking the TWIK-related-potassium channel, type 1 (TREK-1). Here, we examined possible mechanisms of action of spadin at both molecular and cellular levels.Effects of spadin wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff0978fb6442d9c67251c8c61cfb781b
https://pubmed.ncbi.nlm.nih.gov/25598009

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