Zobrazeno 1 - 10
of 76
pro vyhledávání: '"H. Moereels"'
Publikováno v:
Drug Metabolism Reviews. 26:261-285
(1994). Molecular Modeling of Enzymes and Receptors Involved in Carcinogenesis: Qsars and Compacted-3D. Drug Metabolism Reviews: Vol. 26, No. 1-2, pp. 261-285.
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 16:145-154
Dendrograms provide the logical connectedness of the elements of a set, such as proteins that have evolved from common ancestors. The arrangement of the branches of a dendrogram is not unique and many equivalent dendrograms may represent the same log
Publikováno v:
Drug Investigation. 3:3-12
Publikováno v:
Annals of the New York Academy of Sciences. 812
Publikováno v:
Receptorschannels. 5(3-4)
A novel way of classification of G-protein coupled receptors is presented that is only based on receptor sequence information by counting of amino acid residues. It involves the number of amino acid residues between the Asn residue in TM1 and the res
Publikováno v:
Receptorschannels. 4(1)
In this paper, a novel method is presented for classification of 113 neurotransmitter and opioid receptors that is based on the counting of amino acid residues. With the use of sequence alignment, ten conserved key residues were identified: alpha (th
Autor:
Walter Luyten, G. Nobels, W. Gommeren, J. E. Leysen, M. D. De Backer, P. Van Gompel, H. Moereels
Publikováno v:
Biochemical and biophysical research communications. 197(3)
A human histamine H1 receptor gene lacking introns was isolated by screening a human genomic library with a bovine histamine H1 receptor probe. The deduced protein of 487 amino acids showed characteristic properties of G-protein-coupled receptors. Th
Autor:
H, Moereels, J E, Leysen
Publikováno v:
Receptorschannels. 1(2)
With the use of molecular modelling and computational chemistry, two models were obtained showing the binding of dopamine to part of the D2 receptor. These models consist of a molecular complex containing dopamine, the transmembrane domains (TM) 3, 4
Autor:
P. A. J. Janssen, H. Moereels
Publikováno v:
Medical Science Symposia Series ISBN: 9789401048491
With the help of molecular modelling and computational chemistry a number of residues are identified in the 5HT2and 5-HT1Dreceptor protein sequences as being important for the binding of serotonin. In the 5-HT2receptor the following residues are invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b4d153d5e3a37ea06891e367814360
https://doi.org/10.1007/978-94-011-1920-7_13
https://doi.org/10.1007/978-94-011-1920-7_13
Autor:
H. Moereels, Guy Evrard, Sonia Collin, J.P. Tollenaere, Daniel P. Vercauteren, François Durant
Publikováno v:
Journal of molecular structure. 214:159-175
The crystal structures of the title compounds have been solved by direct methods from single crystal X-ray diffraction. Cisapride: monoclinic, space group P 2 1 / n with a =34.210(4), b =7.642(2), c =9.435(1) A, β=90.93(1)°, Z =4, final R factor=0.