Zobrazeno 1 - 10
of 507
pro vyhledávání: '"H. McMurry"'
Autor:
Guohui Sun, Peiying Bai, Tengjiao Fan, Lijiao Zhao, Rugang Zhong, R. Stanley McElhinney, T. Brian H. McMurry, Dorothy J. Donnelly, Joan E. McCormick, Jane Kelly, Geoffrey P. Margison
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2170 (2023)
O6-methylguanine-DNA methyltransferase (MGMT) constitutes an important cellular mechanism for repairing potentially cytotoxic DNA damage induced by guanine O6-alkylating agents and can render cells highly resistant to certain cancer chemotherapeutic
Externí odkaz:
https://doaj.org/article/d48b616a82e846a4806c37a6666ca7ba
Autor:
C. Li, P. H. McMurry
Publikováno v:
Atmospheric Chemistry and Physics, Vol 18, Pp 8979-8993 (2018)
In systems in which aerosols are being formed by chemical transformations, individual particles grow due to the addition of molecular species. Efforts to improve our understanding of particle growth often focus on attempts to reconcile observed gr
Externí odkaz:
https://doaj.org/article/460c123ae09d4507b761ef4c9fa02bf9
Autor:
H. Chen, A. L. Hodshire, J. Ortega, J. Greenberg, P. H. McMurry, A. G. Carlton, J. R. Pierce, D. R. Hanson, J. N. Smith
Publikováno v:
Atmospheric Chemistry and Physics, Vol 18, Pp 311-326 (2018)
Most prior field studies of new particle formation (NPF) have been performed at or near ground level, leaving many unanswered questions regarding the vertical extent of NPF. To address this, we measured concentrations of 11–16 nm diameter partic
Externí odkaz:
https://doaj.org/article/9bfad61330684489bc5677a3f7bc9940
Autor:
A. Kürten, C. Li, F. Bianchi, J. Curtius, A. Dias, N. M. Donahue, J. Duplissy, R. C. Flagan, J. Hakala, T. Jokinen, J. Kirkby, M. Kulmala, A. Laaksonen, K. Lehtipalo, V. Makhmutov, A. Onnela, M. P. Rissanen, M. Simon, M. Sipilä, Y. Stozhkov, J. Tröstl, P. Ye, P. H. McMurry
Publikováno v:
Atmospheric Chemistry and Physics, Vol 18, Pp 845-863 (2018)
A recent CLOUD (Cosmics Leaving OUtdoor Droplets) chamber study showed that sulfuric acid and dimethylamine produce new aerosols very efficiently and yield particle formation rates that are compatible with boundary layer observations. These previo
Externí odkaz:
https://doaj.org/article/9b24a6370d074d138e71a3122016dbf6
Autor:
L. Pichelstorfer, D. Stolzenburg, J. Ortega, T. Karl, H. Kokkola, A. Laakso, K. E. J. Lehtinen, J. N. Smith, P. H. McMurry, P. M. Winkler
Publikováno v:
Atmospheric Chemistry and Physics, Vol 18, Pp 1307-1323 (2018)
Atmospheric new particle formation occurs frequently in the global atmosphere and may play a crucial role in climate by affecting cloud properties. The relevance of newly formed nanoparticles depends largely on the dynamics governing their initial
Externí odkaz:
https://doaj.org/article/7305e1bb85e04b96bfe9dd1453ab96cd
Publikováno v:
Atmospheric Chemistry and Physics, Vol 16, Pp 12513-12529 (2016)
Chemical ionization (CI) mass spectrometers are used to study atmospheric nucleation by detecting clusters produced by reactions of sulfuric acid and various basic gases. These instruments typically use nitrate to deprotonate and thus chemically i
Externí odkaz:
https://doaj.org/article/8294f2b73526479dbedebfd1de3ed097
Autor:
A. L. Hodshire, M. J. Lawler, J. Zhao, J. Ortega, C. Jen, T. Yli-Juuti, J. F. Brewer, J. K. Kodros, K. C. Barsanti, D. R. Hanson, P. H. McMurry, J. N. Smith, J. R. Pierce
Publikováno v:
Atmospheric Chemistry and Physics, Vol 16, Pp 9321-9348 (2016)
New-particle formation (NPF) is a significant source of aerosol particles into the atmosphere. However, these particles are initially too small to have climatic importance and must grow, primarily through net uptake of low-volatility species, from
Externí odkaz:
https://doaj.org/article/b96805e794d54e1db40965ef3e31913e
Autor:
Geoffrey P. Margison, T. Brian H. McMurry, R. Stanley McElhinney, Robert Brown, Malcolm Ranson, Vincent A. Barvaux
Temozolomide is an alkylating agent that mediates its cytotoxic effects via O6-methylguanine (O6-meG) adducts in DNA and their recognition and processing by the postreplication mismatch repair system (MMR). O6-meG adducts can be repaired by the DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aba4fe058932adc997be2d0cec5f709
https://doi.org/10.1158/1535-7163.c.6531875
https://doi.org/10.1158/1535-7163.c.6531875
Autor:
Geoffrey P. Margison, T. Brian H. McMurry, R. Stanley McElhinney, Robert Brown, Malcolm Ranson, Vincent A. Barvaux
Figure 2 from Dual repair modulation reverses Temozolomide resistance in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16df0979b6f37b44b17e26d9e7b09ac3
https://doi.org/10.1158/1535-7163.22485290
https://doi.org/10.1158/1535-7163.22485290
Publikováno v:
Atmospheric Chemistry and Physics, Vol 13, Iss 15, Pp 7631-7644 (2013)
We report the first time-dependent measurements of high-molecular-weight (up to 700 amu) gas-phase oxidation products from α-pinene ozonolysis in an aerosol chamber under dry and low-NOx conditions. Measurements of products having mole fractions ran
Externí odkaz:
https://doaj.org/article/bcc0983b04bc4f4db43c4b0c7a7b9a40