Zobrazeno 1 - 10
of 190
pro vyhledávání: '"H. MacLachlan"'
Autor:
Kelly Hosking, Paula Binks, Teresa De Santis, Phillip Merrdi Wilson, George Garambaka Gurruwiwi, Sarah Mariyalawuy Bukulatjpi, Emily Vintour-Cesar, Melita McKinnon, Peter Nihill, Tammy-Allyn Fernandes, Belinda Greenwood-Smith, Robert Batey, Cheryl Ross, Steven Y.C. Tong, Geoffrey Stewart, Catherine Marshall, Catherine Gargan, Prashanti Manchikanti, Karen Fuller, Jaclyn Tate-Baker, Sami Stewart, Benjamin Cowie, Nicole Allard, Jennifer H. MacLachlan, Ashleigh Qama, David Boettiger, Joshua S. Davis, Christine Connors, Jane Davies
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 48, Iss , Pp 101116- (2024)
Summary: Background: The Northern Territory (NT) has the highest prevalence of chronic hepatitis B (CHB) in Australia. The Hep B PAST program aims to improve health outcomes for people living with CHB. Methods: This mixed methods study involves First
Externí odkaz:
https://doaj.org/article/e640f03b03b949ae9476e4e66d463b6c
Autor:
Anish K. Simhal, Kylee H. Maclachlan, Rena Elkin, Jiening Zhu, Larry Norton, Joseph O. Deasy, Jung Hun Oh, Saad Z. Usmani, Allen Tannenbaum
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The plasma cell cancer multiple myeloma (MM) varies significantly in genomic characteristics, response to therapy, and long-term prognosis. To investigate global interactions in MM, we combined a known protein interaction network with a larg
Externí odkaz:
https://doaj.org/article/8ac2e5a5738b4c569addc774c5791482
Autor:
Jessie J. Goldsmith, Christy Vu, Ziheng Zhu, Jennifer H. MacLachlan, Tilda N. Thomson, Patricia Therese Campbell, Katherine B. Gibney
Publikováno v:
International Journal of Infectious Diseases, Vol 141, Iss , Pp 106969- (2024)
Objectives: To quantify the associations between invasive group A streptococcal disease (iGAS) incidence and influenza, varicella, and chronic hepatitis C virus (HCV). Methods: We used individual-level linked data of iGAS cases from Victoria, Austral
Externí odkaz:
https://doaj.org/article/ddb642d4e20740b1ae82080450c27465
Autor:
Kylee H. Maclachlan, Kezia Gitareja, Jian Kang, Andrew Cuddihy, Yuxi Cao, Nadine Hein, Carleen Cullinane, Ching-Seng Ang, Natalie Brajanovski, Richard B. Pearson, Amit Khot, Elaine Sanij, Ross D. Hannan, Gretchen Poortinga, Simon J. Harrison
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200771- (2024)
The high rates of protein synthesis and processing render multiple myeloma (MM) cells vulnerable to perturbations in protein homeostasis. The induction of proteotoxic stress by targeting protein degradation with proteasome inhibitors (PIs) has revolu
Externí odkaz:
https://doaj.org/article/5496826d98314f02a2fdb22a80a5111f
Autor:
Kylee H. Maclachlan, Even H. Rustad, Andriy Derkach, Binbin Zheng-Lin, Venkata Yellapantula, Benjamin Diamond, Malin Hultcrantz, Bachisio Ziccheddu, Eileen M. Boyle, Patrick Blaney, Niccolò Bolli, Yanming Zhang, Ahmet Dogan, Alexander M. Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Chromothripsis is associated with unfavourable outcomes in multiple myeloma (MM), but its detection usually requires whole genome sequencing. Here the authors develop an approach to detect chromothripsis in MM based on copy-number signatures that als
Externí odkaz:
https://doaj.org/article/b5e6a8716f6d4f72afb2988be3482362
Autor:
Bénedith Oben, Guy Froyen, Kylee H. Maclachlan, Daniel Leongamornlert, Federico Abascal, Binbin Zheng-Lin, Venkata Yellapantula, Andriy Derkach, Ellen Geerdens, Benjamin T. Diamond, Ingrid Arijs, Brigitte Maes, Kimberly Vanhees, Malin Hultcrantz, Elisabet E. Manasanch, Dickran Kazandjian, Alexander Lesokhin, Ahmet Dogan, Yanming Zhang, Aneta Mikulasova, Brian Walker, Gareth Morgan, Peter J. Campbell, Ola Landgren, Jean-Luc Rummens, Niccolò Bolli, Francesco Maura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The factors that are associated with myeloma precursor condition progression are not well understood. Here the authors find that monoclonal gammopathies of undetermined significance and smoldering myelomas that did not progress to multiple myelomas h
Externí odkaz:
https://doaj.org/article/cf7b932cecac4fc1b4e380aa66de4cb0
Autor:
Heather J. Landau, Venkata Yellapantula, Benjamin T. Diamond, Even H. Rustad, Kylee H. Maclachlan, Gunes Gundem, Juan Medina-Martinez, Juan Arango Ossa, Max F. Levine, Yangyu Zhou, Rajya Kappagantula, Priscilla Baez, Marc Attiyeh, Alvin Makohon-Moore, Lance Zhang, Eileen M. Boyle, Cody Ashby, Patrick Blaney, Minal Patel, Yanming Zhang, Ahmet Dogan, David J. Chung, Sergio Giralt, Oscar B. Lahoud, Jonathan U. Peled, Michael Scordo, Gunjan Shah, Hani Hassoun, Neha S. Korde, Alexander M. Lesokhin, Sydney Lu, Sham Mailankody, Urvi Shah, Eric Smith, Malin L. Hultcrantz, Gary A. Ulaner, Frits van Rhee, Gareth J. Morgan, Ola Landgren, Elli Papaemmanuil, Christine Iacobuzio-Donahue, Francesco Maura
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
In multiple myeloma, disease progresses via seeding to different anatomic sites and clonal expansion. Here, utilising autopsy material, the authors show that systemic seeding accelerates at relapse following treatment.
Externí odkaz:
https://doaj.org/article/79126e7bfea74892ac4947e64f7abb17
Autor:
Nicole L. Allard, Jennifer H. MacLachlan, Anouk Dev, James Dwyer, Geeta Srivatsa, Timothy Spelman, Alexander J. Thompson, Benjamin C. Cowie
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Antiviral therapy for chronic hepatitis B (CHB) is effective and can substantially reduce the risk of progressive liver disease and hepatocellular carcinoma but is often administered for an indefinite duration. Adherence has been
Externí odkaz:
https://doaj.org/article/13d61fe7a0604bb88d54ecd0c9176899
Autor:
Jennifer H. MacLachlan, Nicole Romero, Nasra Higgins, Rachel Coutts, Rachel Chan, Nicola Stephens, Benjamin C. Cowie
Publikováno v:
Australian and New Zealand Journal of Public Health, Vol 44, Iss 1, Pp 59-64 (2020)
Abstract Objective: To assess the impact of an enhanced viral hepatitis surveillance program on data completeness and on epidemiological assessment of affected populations. Methods: Notified cases of non‐acute hepatitis B and C were analysed to det
Externí odkaz:
https://doaj.org/article/098eb66a2dcb492383e4bde1119ba1af
Autor:
Francesco Maura, Bachisio Ziccheddu, Jenny Z. Xiang, Bhavneet Bhinder, Joel Rosiene, Federico Abascal, Kylee H. Maclachlan, Kenneth Wha Eng, Manik Uppal, Feng He, Wei Zhang, Qi Gao, Venkata D. Yellapantula, Vicenta Trujillo-Alonso, Sunita I. Park, Matthew J. Oberley, Elizabeth Ruckdeschel, Megan S. Lim, Gerald B. Wertheim, Matthew J. Barth, Terzah M. Horton, Andriy Derkach, Alexandra E. Kovach, Christopher J. Forlenza, Yanming Zhang, Ola Landgren, Craig H. Moskowitz, Ethel Cesarman, Marcin Imielinski, Olivier Elemento, Mikhail Roshal, Lisa Giulino-Roth
Publikováno v:
Blood Cancer Discovery. 4:208-227
The rarity of malignant Hodgkin and Reed Sternberg (HRS) cells in classic Hodgkin lymphoma (cHL) limits the ability to study the genomics of cHL. To circumvent this, our group has previously optimized fluorescence-activated cell sorting to purify HRS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92db280bf9e148c37153d90fb56ce22e
https://doi.org/10.1158/2643-3230.bcd-22-0128
https://doi.org/10.1158/2643-3230.bcd-22-0128