Zobrazeno 1 - 10
of 356
pro vyhledávání: '"H. MAGDELENAT"'
Publikováno v:
Annales Pharmaceutiques Françaises. 63:343-349
Resume Pour degrader les proteines, les cellules eucaryotes disposent de deux systemes principaux de degradation que sont le systeme des proteases lysosomales et le systeme du proteasome, ubiquitine et ATP-dependant. Cette derniere voie de degradatio
Publikováno v:
Endocrine-related cancer. :129-134
The current extension of the indications for adjuvant chemotherapy, which predisposes to early menopause, and the media coverage of the benefits of hormone replacement therapy (HRT) have led patients with a history of breast cancer to seek treatments
Autor:
B Dubray, C. Barbaroux, H Magdelenat, Alain Fourquet, E Gluckman, J M Cosset, M P Chaillet, Jozo Delic, T. Girinsky
Publikováno v:
The British Journal of Radiology. 68:997-1003
Ionizing radiations have been reported as an in vitro apoptosis initiating stimulus in human lymphocytes. As the cytotoxicity of ionizing radiations and chemotherapeutic agents appears to be dependent on the efficacy of cell death induction, the mani
Publikováno v:
Oncology reports. 3(1)
High aerobic glycolysis is frequent in cancers. Glucose phosphorylation is under control of hexokinase which is found in the cytosol or bound to mitochondria. Glycolysis parameters (glucose, pyruvate and lactate) and hexokinase were evaluated in extr
Publikováno v:
Molecular and Cellular Biology. 13:4875-4883
Apoptosis (the classical type of programmed cell death) can be triggered in many cell types by widely diverse stimuli. gamma rays, at low doses, can induce apoptosis in vitro in interphase human lymphocytes. In this type of apoptosis induction, activ
Autor:
M. Namer, H. Magdelenat
Publikováno v:
European Journal of Cancer. 28:1764-1767
Publikováno v:
Mutation Research/Genetic Toxicology. 242:17-23
Unstable chromosome aberrations were scored in peripheral blood lymphocytes (PBL) serially collected from 21 breast cancer patients before and after radiotherapy (RT), chemotherapy (CT) and combined treatments. Local radiotherapy as treatment for mam
Publikováno v:
Mutation Research/Genetic Toxicology. 242:25-35
Lymphocytes from 43 breast cancer patients were tested for their DNA-repair ability and in vitro chromosomal radiosensitivity. Lymphocytes were collected before and after treatment with radiotherapy or chemotherapy or both, and then irradiated in vit
Publikováno v:
Annales pharmaceutiques francaises. 63(5)
Proteasome-mediated proteolysis is a mechanism for mediating important regulatory proteins within the cell. Proteins that have been targeted for degradation by the proteasome are convalently tagged with a poly-ubiquitin protein chain prior to be reco
Publikováno v:
Gynecologie, obstetriquefertilite. 28(5)