Zobrazeno 1 - 9
of 9
pro vyhledávání: '"H. M. Syme"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Hypertension (HTN) and chronic kidney disease (CKD) are common in ageing cats. In humans, blood pressure (BP) and renal function are complex heritable traits. We performed the first feline genome-wide association study (GWAS) of quantitative
Externí odkaz:
https://doaj.org/article/9ba8482a05b84e9cbbc8aea84d7f5795
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-11 (2018)
Abstract Background Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matri
Externí odkaz:
https://doaj.org/article/ad6ae265288b47ffbdeccf6bf45888b9
Autor:
J. S. Lawson, H. M. Syme, P. R. Antrobus, J. M. Karttunen, S. E. Stewart, F. E. Karet Frankl, T. L. Williams
Publikováno v:
The Journal of small animal practiceReferences.
OBJECTIVES: To validate a methodology for isolating feline urinary extracellular vesicles and characterise the urinary extracellular vesicle population and proteome in cats with normal renal function and cats with normotensive or hypertensive chronic
Publikováno v:
The Journal of small animal practice. 57(11)
In humans, genome-wide association studies have identified variants in the uromodulin gene (UMOD) associated with blood pressure and renal function. This study aimed to evaluate the association of single nucleotide polymorphisms at the UMOD locus wit
Publikováno v:
Journal of Veterinary Internal Medicine
Background Identification of risk factors for development of chronic kidney disease (CKD) in cats may aid in its earlier detection. Hypothesis/objectives Evaluation of clinical and questionnaire data will identify risk factors for development of azot
Autor:
C, Crawford, T M, Kennedy-Lydon, H, Callaghan, C, Sprott, R L, Simmons, L, Sawbridge, H M, Syme, R J, Unwin, S S P, Wildman, C M, Peppiatt-Wildman
Publikováno v:
Acta physiologica (Oxford, England). 202(3)
We hypothesized that extracellular nucleotides, established as being released from renal tubular epithelial cells, act at pericytes to regulate vasa recta capillary diameter.A rat live kidney slice model and video imaging techniques were used to inve
Publikováno v:
Journal of veterinary internal medicine. 24(5)
Iatrogenic hypothyroidism can occur after treatment of hyperthyroidism, and is correlated with a reduced glomerular filtration rate in humans and dogs.Cats with iatrogenic hypothyroidism after treatment for hyperthyroidism will have a greater inciden
Publikováno v:
Journal of veterinary internal medicine. 24(4)
Hyperthyroidism complicates the diagnosis of chronic kidney disease (CKD) as it increases glomerular filtration rate. No practical and reliable means for identifying those cats that will develop azotemia after treatment for hyperthyroidism has been i
Autor:
Hans S. Kooistra, Reto Neiger, A. Lloret, I. Villard, H.M. Syme, D. Rosenberg, Peter A. Graham, Federico Fracassi, G. Williams, Sylvie Daminet, Carmel T. Mooney, Angie Hibbert
Publikováno v:
Journal of Small Animal Practice. 55:4-13
Pha rmacological management of feline hyperthyroidism offers a practical treatment option for many hyperthyroid cats. Two drugs have been licensed for cats in the last decade: methimazole and its pro-drug carbimazole. On the basis o f current evidenc