Výsledky vyhledávání - "H. M. Reisner"

Induction of Human Factor VIII Inhibitors in Rats 2: Fine Mapping of Rat anti-Human rFVIII Antibodies

Autor: H. M. Reisner, Janet Harrison, Jerry S. Powell, Michael A. Jarvis, L. G. Levin

Publikováno v: Scopus-Elsevier

SummaryInhibiting antibodies in patients with hemophilia A pose a significant therapeutic dilemma in the treatment of bleeding episodes. The genetic factors which predispose hemophiliacs to inhibitors and the optimal method for inhibitor suppression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ce9600ced179f11818219251a63116
https://doi.org/10.1055/s-0038-1650699

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Induction of Human Factor VIII Inhibitors in Rats by Immunization with Human Recombinant Factor VIII: a Small Animal Model for Humans with High Responder Inhibitor Phenotype

Autor: Michael A. Jarvis, C. L. Ziaja, C. M. Suzuki, D. J. DePianto, Charles F. Abildgaard, Jennifer Brown, Jerry S. Powell, K. W. Jolly, H. M. Reisner, Janet Harrison, L. G. Levin

Publikováno v: Scopus-Elsevier

SummaryHemophilia A is a clotting disorder that is due to reduced or absent coagulation factor VIII (FVIII) activity. In approximately 25% of people with severe hemophilia A, standard treatment with intravenous plasma-derived or recombinant FVIII (rF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00005f3138fb8b073f3d791dbec67081
https://doi.org/10.1055/s-0038-1650268

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Antibody therapy (IVIG): evaluation of the use of genomics and proteomics for the study of immunomodulation therapeutics

Autor: Roger L. Lundblad, C. V. Sapan, H. M. Reisner

Publikováno v: Vox sanguinis. 92(3)

Background and Objectives Intravenous immunoglobulin (IVIG) is used for an increasingly diverse number of therapeutic applications as an immunomodulation drug. Although it has demonstrated therapeutic effectiveness, the mechanism of action of IVIG in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ebdb9a8ca958fddcbfab8def2b4073
https://pubmed.ncbi.nlm.nih.gov/17348868

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TNF-alpha release in monocytes after exposure to calcium hydroxide treated Escherichia coli LPS

Autor: H. M. Reisner, L. G. Levin, Martin Trope, C. R. Barthel

Publikováno v: International endodontic journal. 30(3)

Lipopolysaccharide (LPS), a cell wall component of Gram negative anaerobic bacteria, has been implicated in the pathogenesis of periapical disease resulting from infected root canals. Calcium hydroxide [Ca(OH)2] has been shown to be an effective medi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e73e8a3262c924c87d291e33adf3cef
https://pubmed.ncbi.nlm.nih.gov/9477798

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Induction of human factor VIII inhibitors in rats by immunization with human recombinant factor VIII: a small animal model for humans with high responder inhibitor phenotype

Autor: M A, Jarvis, L G, Levin, J A, Harrison, D J, DePianto, C M, Suzuki, C L, Ziaja, J E, Brown, K W, Jolly, H M, Reisner, C F, Abildgaard, J S, Powell

Publikováno v: Thrombosis and haemostasis. 75(2)

Hemophilia A is a clotting disorder that is due to reduced or absent coagulation factor VIII (FVIII) activity. In approximately 25% of people with severe hemophilia A, standard treatment with intravenous plasma-derived or recombinant FVIII (rFVIII) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c9b9e674951e0f7f09f479ca6d3f02db
https://pubmed.ncbi.nlm.nih.gov/8815584

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Immunogenetics of the human immune response to factor VIII

Autor: H M, Reisner, A, Clark, L, Levin

Publikováno v: Advances in experimental medicine and biology. 386

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::792340a1f8ae0bc000087b125421ed4a
https://pubmed.ncbi.nlm.nih.gov/8851015

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PR 22 Odontoblast express TGF-β and IL-1βb mRNA in response to IFN-γ exposure in vitro

Autor: A Bletsa, H. M. Reisner, Linda Levin, Martin Trope

Publikováno v: Journal of Endodontics. 25:303

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9dc4f83b3767709b1ee6a861c815ba4e
https://doi.org/10.1016/s0099-2399(99)80246-5

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The interaction of bovine prothrombin fragment 1 with metal ions. An immunological approach to kinetic and equilibrium studies

Autor: T J Hall, K A Koehler, H M Reisner, Richard G. Hiskey, D A Madar

Publikováno v: Journal of Biological Chemistry. 255:8599-8605

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9cc4345e2b57f28a2d2a5db710cb29e
https://doi.org/10.1016/s0021-9258(18)43540-5

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Use of monoclonal antibodies in an enzyme immunoassay for factor VIII-related antigen

Autor: L A Bradley, Eduardo L. Franco, H M Reisner

Publikováno v: Scopus-Elsevier

Two monoclonal antibodies (MAb 53, MAb D7) were produced, each having specificity for Factor VIII-related antigen (FVIIIR:Ag), but exhibiting no inhibitory effect on either procoagulant activity or the ability of von Willebrand factor to agglutinate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531abe75b734b4734c3e4bffcc8b6edb
https://doi.org/10.1093/clinchem/30.1.87

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