Pharmacokinetics and Pharmacodynamics of Orally Administered Clonidine: A Model-Based Approach

Autor: Jacobus Burggraaf, Rám N. Sukhai, Boudewijn Bakker, Adam F. Cohen, H M Reeser, P Hu, Erica S. Klaassen, Richard H. Klein, B E P B Ballieux, Wilma Oostdijk, Ricardo Alvarez-Jimenez, J.M. Wit, Jan Freijer

Publikováno v: Hormone Research in Paediatrics, 79(5), 300-309
Klein, R H, Alvarez-Jimenez, R, Sukhai, R N, Oostdijk, W, Bakker, B, Reeser, H M, Ballieux, B E P B, Hu, P, Klaassen, E S, Freijer, J, Burggraaf, J, Cohen, A F & Wit, J M 2013, ' Pharmacokinetics and pharmacodynamics of orally administered clonidine : A model-based approach ', Hormone Research in Paediatrics, vol. 79, no. 5, pp. 300-309 . https://doi.org/10.1159/000350819
Hormone Research in Paediatrics, 79(5), 300-309. S. Karger AG

Background/Aims: The oral clonidine test is a diagnostic procedure performed in children with suspected growth hormone (GH) deficiency. It is associated with untoward effects, including bradycardia, hypotension and sedation. Serum clonidine levels ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ee96142c04000c934356ab6b152d5e
https://doi.org/10.1159/000350819

GH treatment and its effect on bone mineral density, bone maturation and growth in short children born small for gestational age: 3-year results of a randomized, controlled GH trial

Autor: Nicolette J. T. Arends, Jaap Mulder, C Rongen-Westerlaken, V.H. Boonstra, J.J.J. Waelkens, R. J. Odink, H. A. Delemarre-van de Waal, M. Jansen, Wilhelmina H. Stokvis-Brantsma, Paul G.H. Mulder, A.C.S. Hokken-Koelega, H. M. Reeser

Publikováno v: Clinical Endocrinology. 59:779-787

BACKGROUND To investigate in a group of short children born small for gestational age (SGA), the effects of 3 years of GH treatment vs. no treatment on bone age (BA), height and bone mineral density (BMD). Also, to evaluate the influence of the sever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9ef1ce1ff89ee4a0a0d342c7f1d4b91
https://doi.org/10.1046/j.1365-2265.2003.01905.x

Growth response and levels of growth factors after two years growth hormone treatment are similar for a once and twice daily injection regimen in girls with Turner syndrome

Autor: T. Stijnen, H. A. Delemarre-van de Waal, Willem J M Gerver, A. van Teunenbroek, S.M.P.F. de Muinck Keizer-Schrama, J.J.J. Waelkens, J.M. Wit, H. M. Reeser, Stenvert L. S. Drop, T. Vulsma, M. Jansen

Publikováno v: Clinical Endocrinology, 451-459. Wiley-Blackwell Publishing Ltd
ISSUE=46;STARTPAGE=451;ENDPAGE=459;ISSN=0300-0664;TITLE=Clinical Endocrinology

GH is known to improve height velocity in girls with Turner syndrome (TS) but the optimal dosage regimen has yet to be defined. OBJECTIVE We attempted to improve the growth response by trying to mimic normal pulsatile GH secretion more closely. DESIG

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https://doi.org/10.1046/j.1365-2265.1997.1610972.x

GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus

Autor: Johnny, Ludvigsson, David, Krisky, Rosaura, Casas, Tadej, Battelino, Luis, Castaño, James, Greening, Olga, Kordonouri, Timo, Otonkoski, Paolo, Pozzilli, Jean-Jacques, Robert, Henk J, Veeze, Jerry, Palmer, Ulf, Samuelsson, Helena, Elding Larsson, Jan, Åman, Gunilla, Kärdell, Jan, Neiderud Helsingborg, Göran, Lundström, Eva, Albinsson, Annelie, Carlsson, Maria, Nordvall, Hans, Fors, Carl-Göran, Arvidsson, Stig, Edvardson, Ragnar, Hanås, Karin, Larsson, Björn, Rathsman, Henrik, Forsgren, Helena, Desaix, Gun, Forsander, Nils-Östen, Nilsson, Carl-Göran, Åkesson, Päivi, Keskinen, Riitta, Veijola, Timo, Talvitie, Klemens, Raile, Thomas, Kapellen, Walter, Burger, Andreas, Neu, Ilse, Engelsberger, Bettina, Heidtmann, Suzanne, Bechtold, David, Leslie, Francesco, Chiarelli, Alesandro, Cicognani, Giuseppe, Chiumello, Franco, Cerutti, Gian Vincenzo, Zuccotti, Ana, Gomez Gila, Itxaso, Rica, Raquel, Barrio, Maria, Clemente, Maria José, López Garcia, Mercedes, Rodriguez, Isabel, Gonzalez, Juan Pedro, Lopez, Mirentxu, Oyarzabal, H M, Reeser, Roos, Nuboer, Pauline, Stouthart, Natasa, Bratina, Nina, Bratanic, Marc, de Kerdanet, Jacques, Weill, Nicole, Ser, Pascal, Barat, Anne Marie, Bertrand, Jean-Claude, Carel, Rachel, Reynaud, Regis, Coutant, Sabine, Baron

Publikováno v: The New England journal of medicine. 366(5)

The 65-kD isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes. We hypothesized that alum-formulated GAD65 (GAD-alum) can preserve beta-cell function in patients with recent-onset type 1 diabetes.We studied 334 pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a576e430b0435bf3bd36fb2c21207ef6
https://pubmed.ncbi.nlm.nih.gov/22296077

Diabetes mellitus

Autor: H. M. Reeser

Publikováno v: Ziekten en handicaps ISBN: 9789031378333

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa883f56ba6a94d72423c2b289e5dbe8
https://doi.org/10.1007/978-90-313-7834-0_6