Zobrazeno 1 - 10
of 29
pro vyhledávání: '"H. M. J. Krans"'
Autor:
Job Kievit, H. M. J. Krans, A. P. van Seters, H. van Dulken, Jo Hermans, S. K. Nagesser, C.J.H. van de Velde
Publikováno v:
Clinical Endocrinology. 52:427-435
Summary BACKGROUND The preferred treatment of Cushing's disease (CD) nowadays is transsphenoidal pituitary surgery (TPS). Prior to TPS, patients at the Leiden University Medical Centre were treated by unilateral adrenalectomy followed by external pit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f200ac0281b0f69742c6a7c310bc52
https://doi.org/10.1046/j.1365-2265.2000.00958.x
https://doi.org/10.1046/j.1365-2265.2000.00958.x
Autor:
H. M. J. Krans, A. Kuipers, J. A. Maassen, E. R. Van Der Vorm, S. Kielkopf-Renner, Wim Möller
Publikováno v:
Journal of Biological Chemistry. 269:14297-14302
Here we report the identification of a new mutation in the alpha-chain of the insulin receptor, changing Trp412 into Ser using DNA from consanguineous parents who gave birth to a child with leprechaunism. The mutant receptor was expressed stably in C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b04297d6e8c176e4a7af6d752bccadff
https://doi.org/10.1016/s0021-9258(17)36788-1
https://doi.org/10.1016/s0021-9258(17)36788-1
Autor:
van de Velde Cj, Gert Jan Fleuren, E. G. W. M. Lentjes, Harm R. Haak, H. M. J. Krans, Goslings Bm, Jo Hermans
Publikováno v:
British Journal of Cancer
Mitotane is considered to be the drug of choice for patients with inoperable, recurrent and metastatic adrenocortical carcinoma, although a favourable effect of this drug on survival has never been documented. We evaluated the efficacy of mitotane tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5230064579c702a1e5c6628bde413020
http://europepmc.org/articles/PMC1968906
http://europepmc.org/articles/PMC1968906
Publikováno v:
Diabetes research and clinical practice, 12(1), 1-9. Elsevier Ireland Ltd
To study the effects of CSII on insulin action and intermediary metabolism, seven type 1 diabetic patients (duration 17 +/- 4 (SEM) years), underwent sequential euglycemic clamps 1/4, 6 and 12 months after changing from conventional insulin treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975951e00a1b87661f79596183dc44de
https://doi.org/10.1016/0168-8227(91)90124-v
https://doi.org/10.1016/0168-8227(91)90124-v
Publikováno v:
Diabetes. 39:333-339
The relationship between plasma clearance rate of insulin (PCR) and insulin-stimulated glucose disposal was investigated in 15 healthy subjects and 30 insulin-dependent diabetes mellitus (IDDM) patients with the sequential euglycemic (5 mMj clamp tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a30b06bafb60e4b458daaaa0028d65
https://doi.org/10.2337/diab.39.3.333
https://doi.org/10.2337/diab.39.3.333
Autor:
G. J. Ligthart, J. Frenken, R. Janknegt, C. de Baat, P. A. F. Jansen, J. W. M. van der Meer, J.H. Dijkman, B. J. Vermeer, Freek W.A. Verheugt, G. C. H. M. van der Aa, F. W. Jansen, H. M. J. Krans, E. E. van der Wall, M. J. J. Olofsen-van Acht, W. Kalk, M. Afschrift, H. J. M. Cools, Rein Willemze
Publikováno v:
Inleiding gerontologie en geriatrie ISBN: 9789031342648
In dit hoofdstuk komen orgaanaandoeningen aan de orde die invloed hebben op de gezondheid van de oudere mens. Hart- en vaatziekten komen veel voor, vooral coronairlijden, hartfalen, geleidingsstoornissen en hartkleplijden. Door de verbeterde overlevi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74e969b019b868ef61a94813793443c3
https://doi.org/10.1007/978-90-313-6529-6_9
https://doi.org/10.1007/978-90-313-6529-6_9
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 107(8)
The EURODIAB IDDM Complications Study, a cross-sectional, clinic-based study examined the fat and cholesterol intakes of European individuals with type 1 diabetes for possible relations to serum lipid levels (total cholesterol, HDL- and LDL-cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb921e42279e2955237dda05a20c82f
https://pubmed.ncbi.nlm.nih.gov/10612482
https://pubmed.ncbi.nlm.nih.gov/10612482
Publikováno v:
Diabetologia. 39(4)
Short-term exposure of tissues to pulses of insulin generally leads to an enhancement of insulin action. We have investigated the possible beneficial effects of long-term near-physiological continuous vs pulsatile intravenous insulin treatment of ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c7fd8fd9f52ac2a6ab5d4da35fd2a6
https://pubmed.ncbi.nlm.nih.gov/8777988
https://pubmed.ncbi.nlm.nih.gov/8777988
Publikováno v:
Metabolism: clinical and experimental. 44(3)
Insulin action is subject to regulation at the level of the insulin receptor and at postreceptor levels. Starvation and diabetes are often associated with insulin resistance for glucose metabolism in various tissues. In muscle, fat, and liver, we exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a168be16efd348e0e6441fe7d48440
https://pubmed.ncbi.nlm.nih.gov/7885272
https://pubmed.ncbi.nlm.nih.gov/7885272
Autor:
Wim Möller, G.C.M. van der Zon, H. M. J. Krans, M. P. Klinkhamer, E. R. Van Der Vorm, Johannes A Maassen
Publikováno v:
Biochemistry. 30(44)
We have previously shown that a homozygous mutation encoding a substitution of proline for leucine at position 233 in the insulin receptor is linked with the syndrome of leprechaunism, being a lethal form of insulin resistance in newborn children. Sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9e6f1d13c4923d7b1949bc0a0b7835
https://pubmed.ncbi.nlm.nih.gov/1931997
https://pubmed.ncbi.nlm.nih.gov/1931997