Zobrazeno 1 - 10
of 236
pro vyhledávání: '"H. Loomis"'
Autor:
Mary F. Barbe, Frank Liu Chen, Regina H. Loomis, Michele Y. Harris, Brandon M. Kim, Kevin Xie, Brendan A. Hilliard, Elizabeth R. McGonagle, Taylor D. Bailey, Ryan P. Gares, Megan Van Der Bas, Betsy A. Kalicharan, Lewis Holt-Bright, Laura S. Stone, Paul W. Hodges, David M. Klyne
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
IntroductionLow back pain is the most common type of chronic pain. We examined pain-related behaviors across 18 weeks in rats that received injury to one or two lumbar intervertebral discs (IVD) to determine if multi-level disc injuries enhance/prolo
Externí odkaz:
https://doaj.org/article/4175a90459b149eba642bec0558cc594
Autor:
Kristin H. Loomis, Susan K. Wu, Amanda Ernlund, Kristina Zudock, Allison Reno, Kianna Blount, David K. Karig
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Background Skin, the largest organ of the human body by weight, hosts a diversity of microorganisms that can influence health. The microbial residents of the skin are now appreciated for their roles in host immune interactions, wound healing
Externí odkaz:
https://doaj.org/article/d483ec74b87a4d68a4f02a4d471aa4f9
Autor:
Emmeline L. Blanchard, Kristin H. Loomis, Sushma M. Bhosle, Daryll Vanover, Patrick Baumhof, Bruno Pitard, Chiara Zurla, Philip J. Santangelo
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 52-66 (2019)
The characterization of innate immune activation is crucial for vaccine and therapeutic development, including RNA-based vaccines, a promising approach. Current measurement methods quantify type I interferon and inflammatory cytokine production, but
Externí odkaz:
https://doaj.org/article/ce9a7b51eb514c22a442138d2bda3bc5
Autor:
Kate Zidar, Timothy A. Bartrand, Charles H. Loomis, Chariss A. McAfee, Juliet M. Geldi, Gavin J. Rigall, Franco Montalto
Publikováno v:
Urban Planning, Vol 2, Iss 4, Pp 115-132 (2017)
While the Philadelphia Water Department (PWD) is counting on Green Stormwater Infrastructure (GI) as a key component of its long-term plan for reducing combined sewer overflows, many community stakeholders are also hoping that investment in greening
Externí odkaz:
https://doaj.org/article/28b1d76c6387464fb64e2df040fc23a2
Publikováno v:
Clinics, Vol 63, Iss 3, Pp 321-328 (2008)
OBJECTIVE: The objective of this study was to determine the effect of nonspecific phosphodiesterase inhibition on transcription factor activation and tumor necrosis factor-alpha (TNF-a) production in lipopolysaccharide (LPS)-stimulated human mononucl
Externí odkaz:
https://doaj.org/article/d8428c01cb424f3e9e1acb950d75d177
Autor:
Kristina K Zudock, Allison Reno, Susan K. Wu, Amanda Ernlund, Kristin H. Loomis, Kianna M Blount, David K. Karig
Publikováno v:
Microbiome
Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)
Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)
Background Skin, the largest organ of the human body by weight, hosts a diversity of microorganisms that can influence health. The microbial residents of the skin are now appreciated for their roles in host immune interactions, wound healing, coloniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c7b75ac50e7bdecdd930ec7e722a65
https://doi.org/10.1186/s40168-020-00963-1
https://doi.org/10.1186/s40168-020-00963-1
Autor:
Philip J. Santangelo, Ravi V. Bellamkonda, Sushma M. Bhosle, Kristin H. Loomis, Jonathan L. Kirschman
Publikováno v:
Journal of materials chemistry. B. 4(9)
Synthetic mRNA has recently shown great potential as a tool for genetic introduction of proteins. Its utility as a gene carrier has been demonstrated in several studies for both the introduction of therapeutic proteins and subunit vaccines. At one po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b9b37c3591df40f831e20310ab8269
https://pubmed.ncbi.nlm.nih.gov/32263015
https://pubmed.ncbi.nlm.nih.gov/32263015
Autor:
Kristin H. Loomis, Jonathan L. Kirschman, Kevin E. Lindsay, Philip J. Santangelo, Ravi V. Bellamkonda, Chiara Zurla, Daryll Vanover, Emmeline L. Blanchard, Sushma M. Bhosle
Publikováno v:
Bioconjugate Chemistry. 29:3072-3083
In vitro transcribed (IVT) mRNA is an appealing platform for next generation vaccines, as it can be manufactured rapidly at large scale to meet emerging pathogens. However, its performance as a robust vaccine is strengthened by supplemental immune st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fcc65d0770ac3006dbc355d126857f
https://doi.org/10.1021/acs.bioconjchem.8b00443
https://doi.org/10.1021/acs.bioconjchem.8b00443
Autor:
Sushma M. Bhosle, Philip J. Santangelo, Damien Habrant, Kristin H. Loomis, Jonathan L. Kirschman, Chiara Zurla, Daryll Vanover, Bruno Pitard, Patrick Baumhof, Emmeline L. Blanchard, Darin K. Edwards
Publikováno v:
Biomaterials. 159:189-203
The translational efficiency of an in vitro transcribed (IVT) mRNA was measured upon delivery to primary skeletal muscle cells and to a mouse model system, towards the development of a predictive in vitro assay for the screening and validation of int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8336935a144662461febbab2d3b0f4c4
https://doi.org/10.1016/j.biomaterials.2018.01.010
https://doi.org/10.1016/j.biomaterials.2018.01.010
Autor:
Todd W. Costantini, Brian P. Eliceiri, Carrie Y. Peterson, William H. Loomis, James G. Putnam, Andrew Baird, Paul Wolf, Vishal Bansal, Raul Coimbra
Publikováno v:
Molecular Imaging, Vol 9 (2010)
Intestinal injury owing to inflammation, severe trauma, and burn is a leading cause of morbidity and mortality. Currently, animal models employed to study the intestinal response to injury and inflammation depend on outdated methods of analysis. Give
Externí odkaz:
https://doaj.org/article/df9b93311e6b4e83bca0ca9e78e08e63