Zobrazeno 1 - 10
of 96
pro vyhledávání: '"H. Lecar"'
Publikováno v:
Proceedings of the National Academy of Sciences. 86:7866-7870
A mutant in the plasma membrane H+-ATPase gene of the yeast Saccharomyces cerevisiae with a reduced H+-ATPase activity, when examined at the single-channel level with the patch-clamp technique, was found to exhibit K+ channels activated by intracellu
Publikováno v:
Biophysical Journal. 42(1):109-114
Previous analysis of single-channel current records has shown that both the opening and closing transitions of chemically activated ion channels are operated by fast and slow kinetic processes. The fast component in the kinetics of channel opening ha
Publikováno v:
The Journal of Membrane Biology. 21:25-47
Measurements of the resistance in series with the excitable membrane for giant axons of two different phylla (the squid Loligo pealii and the marine worm Myxicola infundibulum) were obtained. Efforts were made to take into account the errors introduc
Autor:
Catherine E. Morris, H. Lecar
Publikováno v:
Biophysical Journal. (1):193-213
Barnacle muscle fibers subjected to constant current stimulation produce a variety of types of oscillatory behavior when the internal medium contains the Ca++ chelator EGTA. Oscillations are abolished if Ca++ is removed from the external medium, or i
Publikováno v:
Biophysical Journal. (3):313-317
Single Ca2+-dependent K+-channel currents were recorded in intact and excised inside-out membrane patches of the anterior pituitary clone AtT-20/D16-16. The frequency of channel openings and lifetimes depends both on membrane potential and on the Ca2
Autor:
H. Lecar, K. S. Cole
Publikováno v:
The Journal of membrane biology. 25(1-2)
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2(10)
Single cholinergic channel currents were recorded in adult human muscle tissue culture. The agonists suberyldicholine and carbamylcholine produce channels with the same conductance as channels produced by acetylcholine but with different closing kine
Autor:
Frederick Sachs, H. Lecar
Publikováno v:
Biophysical journal. 17(2)
Acetylcholine applied ionophoretically to chick skeletal muscle cells grown in tissue culture produces membrane current fluctuations. Cells treated with vinblastine are transformed to a roughly spherical shape. Such transformed cells can be voltage-c
Parallel electrophysiological and neurochemical studies of development are reported for mouse spinal cord cell cultures. The time course of electrical activity and the stage-dependent effects of tetrodotoxin on levels of the neuronal enzyme choline a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44caba0a7c3e3321ea68be3fde0886ed
https://europepmc.org/articles/PMC6564276/
https://europepmc.org/articles/PMC6564276/
Autor:
H, Lecar
Publikováno v:
Federation proceedings. 44(15)
Fluctuating ionic currents caused by the activation of individual ionic channels can be observed in excitable membranes. These single-channel currents allow experimenters to characterize the stochastic properties of the membrane protein conformationa