Zobrazeno 1 - 10
of 194
pro vyhledávání: '"H. Lazar"'
Publikováno v:
Journal of Intensive Care Medicine. 38:21-26
Purpose: Elevated ferritin levels are associated with poor outcomes in Covid-19 patients. Optimal timing of ferritin assessment and the merit of longitudinal values remains unclear. Methods: Patients admitted to Henry Ford Hospital with confirmed SAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9600ce3606fb727d491b96c4eadc55c
https://doi.org/10.1177/08850666221113252
https://doi.org/10.1177/08850666221113252
Autor:
Nathan H. Lazar, Safiye Celik, Lu Chen, Marta Fay, Jonathan C. Irish, James Jensen, Conor A. Tillinghast, John Urbanik, William P. Bone, Genevieve H. L. Roberts, Christopher C. Gibson, Imran S. Haque
SummaryCRISPR-Cas9 editing is a scalable technology for mapping of biological pathways, but it has been reported to cause a variety of undesired large-scale structural changes to the genome. We performed an arrayed CRISPR-Cas9 scan of the genome in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13a0dbf22269b50e5805eafaa6f2dcda
https://doi.org/10.1101/2023.04.15.537038
https://doi.org/10.1101/2023.04.15.537038
Autor:
Safiye Celik, Jan-Christian Hütter, Sandra Melo Carlos, Nathan H Lazar, Rahul Mohan, Conor Tillinghast, Tommaso Biancalani, Marta Fay, Berton A Earnshaw, Imran S Haque
The continued scaling of genetic perturbation technologies combined with high-dimensional assays (microscopy and RNA-sequencing) has enabled genome-scale reverse-genetics experiments that go beyond single-endpoint measurements of growth or lethality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456229671e628931109c0f1826778fcb
https://doi.org/10.1101/2022.12.09.519400
https://doi.org/10.1101/2022.12.09.519400
Autor:
Erin P. McDonnell, Nicole J. Altomare, Yesha H. Parekh, Ram C. Gowda, Payal D. Parikh, Mark H. Lazar, Martin J. Blaser
Publikováno v:
Pathogens, Vol 9, Iss 11, p 965 (2020)
Coronavirus 2019 (COVID-19) has been reported to trigger Guillain–Barré syndrome (GBS). While uncommon, recurrent GBS (rGBS) episodes, triggered by antecedent viral infections, have been reported in a small proportion of GBS patients, here we desc
Externí odkaz:
https://doaj.org/article/d9652020a4ba4f85a384e457d689ba05
Autor:
Evelyn Erzsébet Gabri, Octavian Popescu, Réka Ilona Jakab, Tamás József Mészáros, Bernadett Kremmer, Csilla H. Lazar, Ágnes Katona, Edina Török, Endre Jakab, Liliana Coldea, Mircea Colcieru, Enikő Fazakas
Publikováno v:
Microbial Drug Resistance. 25:639-643
In the last few decades, methicillin-resistant Staphylococcus aureus (MRSA) strains have become a serious health care problem. However, in the European Union/European Economic Area countries the pr...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1518f1de3ba9673081d49030aa644e65
https://doi.org/10.1089/mdr.2018.0205
https://doi.org/10.1089/mdr.2018.0205
Publikováno v:
Journal of Intensive Care Medicine. 35:1471-1475
Objective: The purpose of this study is to determine whether in patients admitted to a medical intensive care unit (ICU) service there are outcome differences between those in a medical ICU bed (“home”) and a geographically distant subspecialty I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6548fd39070db3eb31d0fc607a083908
https://doi.org/10.1177/0885066619835488
https://doi.org/10.1177/0885066619835488
Autor:
Brittany L. Daughtry, Andrew Adey, Nash Redmayne, Lina Gao, Kristof A. Torkenczy, Nathan H. Lazar, Byung Park, Jimi L. Rosenkrantz, Kimberly A. Nevonen, Suzanne S. Fei, Melissa Y. Yan, Lucia Carbone, Shawn L. Chavez
Publikováno v:
Genome Research. 29:367-382
Aneuploidy that arises during meiosis and/or mitosis is a major contributor to early embryo loss. We previously showed that human preimplantation embryos encapsulate missegregated chromosomes into micronuclei while undergoing cellular fragmentation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c9c78c00da6439b24fe5a8bd9aad1a
https://doi.org/10.1101/gr.239830.118
https://doi.org/10.1101/gr.239830.118
Autor:
Jeffrey H. Jennings, Jayna Gardner-Gray, Geneva Tatem, Martina T Caldwell, Raef Fadel, Jennifer Swiderek, Michael H. Lazar
Publikováno v:
Critical Care Medicine
OBJECTIVES: To investigate the potential influence of racial differences in outcomes of patients infected by coronavirus disease 2019-positive patients who require intensive care in an urban hospital. DESIGN: Retrospective cohort study. SETTING: Henr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8fff3df064b8a15aff564b13c0f9c9b
https://pubmed.ncbi.nlm.nih.gov/33616353
https://pubmed.ncbi.nlm.nih.gov/33616353
Autor:
Yolanda T. Chong, Vlad Rodic, Fiona L. Weathersby, Carl A. Brooks, Michael F. Cuccarese, Nathan H. Lazar, Ian K. Quigley, Christopher C. Gibson, Ronald W. Alfa, Berton A. Earnshaw, Kirk R. Thomas, Michael A. Statnick, Brandon L. Probst, Ben Fogelson, Nicholas D. Campbell, Jes Ford, Kathleen-Rose Skelly, Mason L. Victors, Seth W. Glazier, Peter F. McLean, James D. Jensen, Imran S. Haque, Anne E. Carpenter, Sharath S. Hegde, Chadwick T. Davis, Katie Heiser, Pamela Jacobson, Brandon M. Mendivil, Adeline S. Low, Joseph Carpenter, Elissa D. Pastuzyn, Hannah B. Gordon
Development of accurate disease models and discovery of immune-modulating drugs is challenged by the immune system’s highly interconnected and context-dependent nature. Here we apply deep-learning-driven analysis of cellular morphology to develop a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9c21782616d4199bcf88ffc3650d4b4
https://doi.org/10.1101/2020.08.02.233064
https://doi.org/10.1101/2020.08.02.233064
Autor:
David P. Gavin, Joel G. Hashimoto, Nathan H. Lazar, Lucia Carbone, John C. Crabbe, Marina Guizzetti
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics
Frontiers in Genetics
Alcohol use disorder (AUD) is a chronic mental illness in which patients often achieve protracted periods of abstinence prior to relapse. Epigenetic mechanisms may provide an explanation for the persisting gene expression changes that can be observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9e89f7bb74430f1093357d478ad80a
https://doi.org/10.3389/fgene.2018.00346
https://doi.org/10.3389/fgene.2018.00346