Zobrazeno 1 - 10
of 24
pro vyhledávání: '"H. L. Weith"'
Publikováno v:
Bioconjugate Chemistry. 6:473-482
Four benzophenanthridine phosphoramidite reagents have been prepared in which the linker chain between the benzophenanthridine and the phosphoramidite moiety is attached to C-2, C-6, C-9, and C-12 of the benzophenanthridine ring system. These benzoph
Publikováno v:
ChemInform. 26
Four benzophenanthridine phosphoramidite reagents have been prepared in which the linker chain between the benzophenanthridine and the phosphoramidite moiety is attached to C-2, C-6, C-9, and C-12 of the benzophenanthridine ring system. These benzoph
Autor:
Jer-kang Chen, W.P. Ma, Joseph G. Stowell, K.A. Ray, H. L. Weith, Charles Pidgeon, Dean Carlson, Stephen R. Byrn, Mark Cushman, M.E. Goldman
Publikováno v:
Advanced Drug Delivery Reviews. 6:287-308
In this review, drug oligonucleotide conjugates synthesized and characterized in our laboratories will be discussed. An idealized view of a complex between an acridine-oligonucleotide conjugate and RNA is shown above. In addition, other related conju
Autor:
Dean Carlson, Mark Cushman, Stephen R. Byrn, Charles Pidgeon, D. Darbishire-Weith, K.A. Ray, H. L. Weith, Jer-kang Chen, Joseph G. Stowell
Publikováno v:
Annals of the New York Academy of Sciences. 616:593-596
Publikováno v:
Biochemistry. 23:6153-6159
Two new protected 5'-ribonucleotides, 2'3'-O-bis(4,4'-dimethoxytrityl)uridine 5'-(4-chlorophenyl phosphate) and 2',3'-O-(methoxymethylene)uridine 5'-(4-chlorophenyl phosphate), form the basis of a chemical procedure for phosphorylating the 5'-ends of
Publikováno v:
Journal of Biological Chemistry. 257:10372-10377
Pancreatic poly(A) RNA isolated from the channel catfish (Ictalurus punctatus) was enriched for sequences corresponding to somatostatin mRNA on isokinetic sucrose gradients. Double-stranded cDNA was synthesized and inserted into the Pst I site pBR322
Publikováno v:
Journal of Molecular Biology. 92:377-393
The nucleotide sequence of the principal bacteriophage φX174 ribosome-protected DNA fragment has been determined. Details of the approaches and methods used for direct DNA sequence analysis are described, The resulting sequence allows prediction of
Publikováno v:
Journal of Bacteriology. 162:943-949
In Salmonella typhimurium, expression of the leucine operon is regulated by a transcription attenuation mechanism. According to a current model of attenuation, elevated expression of this operon requires that a ribosome stall at one of four adjacent
Autor:
M A Tavianini, Marilyn Magazin, Jack E. Dixon, Robert J. Deschenes, David C. Aron, C D Minth, K. Collier, M. Sheets, Bernard A. Roos, H L Weith, C. L. Funckes
Publikováno v:
Journal of Biological Chemistry. 258:8781-8787
An undecanucleotide extended hybridization probe has been used to screen a rat medullary thyroid carcinoma cDNA library for clones which contain preprosomatostatin sequences. The nucleotide sequence encoding rat preprosomatostatin is reported. The se
Autor:
T G Lawson, B K Ray, J T Dodds, R D Abramson, H L Weith, Robert E. Thach, D F Betsch, J A Grifo, William C. Merrick
Publikováno v:
Journal of Biological Chemistry. 261:13979-13989
The effects of 5' proximal secondary structure in mRNA molecules on their translation and on their interaction with the eukaryotic initiation factors (eIF)-4F, eIF-4A, and eIF-4B have been examined. Secondary structures were generated in the 5' nonco