Zobrazeno 1 - 3
of 3
pro vyhledávání: '"H. L. Leidy"'
Publikováno v:
Journal of Chromatography. 308:251-259
The pivaloyloxyethyl ester of methyldopa is an antihypertensive prodrug possessing improved bioavailability properties over methyldopa. A sensitive cation-exchange, high-performance liquid chromatographic assay using electrochemical detection has bee
Autor:
S, Vickers, C A, Duncan, H G, Ramjit, M R, Dobrinska, C T, Dollery, H J, Gomez, H L, Leidy, W C, Vincek
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 12(2)
In a crossover study, the pivaloyloxyethyl ester (POE) of methyldopa, labeled either with 3H in the methyldopa moiety or 14C in the pivalic acid moiety, was administered orally to four volunteers in 1000-mg single doses (equivalent to 500 mg of methy
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 125(4)