Výsledky vyhledávání - "H. L. Hosick"

Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells

Autor: T G, Ram, H L, Hosick, S P, Ethier

Publikováno v: Journal of cellular physiology. 183(3)

The neu differentiation factors/heregulins (HRGs) comprise a family of polypeptide growth factors that activate p185(erbB-2) through direct binding to either erbB-3 or erbB-4 receptor tyrosine kinases. We have previously shown that HRG-beta is mitoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::89125471efa65aad89d2b4f1587ee993
https://pubmed.ncbi.nlm.nih.gov/10797304

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Blocking HER-2/HER-3 function with a dominant negative form of HER-3 in cells stimulated by heregulin and in breast cancer cells with HER-2 gene amplification

Autor: T G, Ram, M E, Schelling, H L, Hosick

Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 11(3)

Amplification and overexpression of the HER-2 (neu/ erbB-2) gene in human breast cancer are clearly important events that lead to the transformation of mammary epithelial cells in approximately one-third of breast cancer patients. Heterodimer interac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::82d7f935a35e31fe4d9c13790d60d641
https://pubmed.ncbi.nlm.nih.gov/10768865

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Traditional and emerging methods for analyzing cell activity in cell culture

Autor: N T, Stewart, K M, Byrne, H L, Hosick, J L, Vierck, M V, Dodson

Publikováno v: Methods in cell science : an official journal of the Society for In Vitro Biology. 22(1)

The selection of appropriate techniques to assay for markers of cell activity is important for obtaining optimal results in cell culture-based research. This paper is intended as a guide to many of the assays currently available and new techniques th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c07a5e09cb738b861648f5cb2ca6a290
https://pubmed.ncbi.nlm.nih.gov/10650337

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Effects of dietary conjugated linoleic acid on lymphocyte function and growth of mammary tumors in mice

Autor: M W, Wong, B P, Chew, T S, Wong, H L, Hosick, T D, Boylston, T D, Shultz

Publikováno v: Anticancer research. 17(2A)

We studied the effects of conjugated linoleic acid (CLA) on lymphocyte function and growth of a transplantable murine mammary tumor. In experiment 1, eight-wk-old female Balb/c mice (n = 8/group) were fed 0.1%, 0.3% or 0.9% CLA for 3 or 6 wk. Lymphoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3de8f23e4281dccaf93b19b46ba0755b
https://pubmed.ncbi.nlm.nih.gov/9137439

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Expression of epidermal growth factor-related proteins in the aged adult mouse mammary gland and their relationship to tumorigenesis

Autor: E E, Herrington, T G, Ram, D S, Salomon, G R, Johnson, W J, Gullick, N, Kenney, H L, Hosick

Publikováno v: Journal of cellular physiology. 170(1)

Mammary glands from female BALB/c mice of different ages and parity were screened for production of three epidermal growth factor (EGF) related transforming growth factors and their corresponding mRNAs. Glands were obtained from 2-26-month-old nullip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6208e0d64b3550b4a7b15915473cba82
https://pubmed.ncbi.nlm.nih.gov/9012784

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Salivary mesenchyme cells that induce mammary epithelial hyperplasia up-regulate EGF receptors in primary cultures of mammary epithelium within collagen gels

Autor: V, Venkateswaran, S A, Oliver, T G, Ram, H L, Hosick

Publikováno v: Growth regulation. 3(2)

Salivary mesenchyme is a potent stimulator of mammary epithelial hyperplasia and carcinogen-induced tumor formation in vivo. We have utilized a three-dimensional collagen gel culture system, which mimics the in vivo growth environment, to identify gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cda8cae5c0b6227af4ddc5863274e3b9
https://pubmed.ncbi.nlm.nih.gov/8339047

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Clonal Behavior of a Rat Liver Cell Line and Its Modification by Repeated Treatments With a Carcinogenic Polycyclic Hydrocarbon 2

Autor: J. R. Starkey, H. L. Hosick

Publikováno v: JNCI: Journal of the National Cancer Institute. 59:859-866

A rat liver cell line, Lew A1, was isolated from W/LEW rats. It had the normal female karyotype in the lower passage numbers, but in the higher passages it was aneuploid. This line was passaged 65 times, produced rat serum albumin, and consisted of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4460ec80c62febd469da43bc0949e2c6
https://doi.org/10.1093/jnci/59.3.859

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Novel multialveolar epithelial structures from rabbit mammary gland that synthesize milk specific fatty acids in response to prolactin

Autor: Raymond R. Dils, H. L. Hosick, C. A. Carrington, I. A. Forsyth

Publikováno v: In Vitro. 17:363-368

Multialveolar mammary epithelial structures have been prepared from rabbit mammary gland by treating the tissue with collagenase plus hyaluronidase. These structures synthesize milk specific fatty acids when cultured with physiological concentrations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696407e87467e4395403c16c46cdbc09
https://doi.org/10.1007/bf02626733

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