Zobrazeno 1 - 10
of 11
pro vyhledávání: '"H. L. Allan Tse"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:1387-1392
The synthesis of constrained analogues of 2′-nor-cyclic nucleosides monophosphates containing a thiomethylene tether was readily accomplished from the oxathiolane intermediate 4 . The uracil, cytosine, and 5-bromocytosine spirophosphate analogues 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb9e99afaaf08c0a3f696dc460c6593a
https://doi.org/10.1016/s0960-894x(97)00245-x
https://doi.org/10.1016/s0960-894x(97)00245-x
Autor:
John Gillard, Claire Ashman, Horacio Salomon, Elizabeth Hooker, Haolun Jin, Antonietta R. Belmonte, Nick Cammack, Colleen A. Evans, Wei Wang, Mark A. Wainberg, Bernard Belleau, Dilip M. Dixit, Tarek S. Mansour, H. L. Allan Tse
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 14:627-635
3′-Oxa-4′-thiocytidine nucleoside analogues 14–17 were prepared from oxathiolanes 10 and 11, and evaluated for activity against HIV-1 and HBV in vitro. The nucleoside analogues were found to possess potent activities against HIV-1 in a panel of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2ba7d2627716e74f77ad3cbc8db6125
https://doi.org/10.1080/15257779508012439
https://doi.org/10.1080/15257779508012439
Autor:
H. L. Allan Tse, Marie Charron, D. J. Knight, Tarek S. Mansour, Jonathan Coates, Corrine O'Sullivan
Publikováno v:
Heteroatom Chemistry. 5:491-496
A convenient synthesis of 1-(8-phosphonomethoxy-3,6-dioxaoctyl) uracil, cytosine, adenine, and guanine nucleotide analogues 26, 28, 30, and 32 by Mitsunobu coupling of the nucleobases with suitably functionalized alcohol derivative 24 is described. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::328373bb9a7d8b4ef2d8585558598392
https://doi.org/10.1002/hc.520050512
https://doi.org/10.1002/hc.520050512
Autor:
Tarek S. Mansour, Marika P. Dimarco, H. L. Allan Tse, Haolun Jin, M. Arshad Siddiqui, Colleen A. Evans
Publikováno v:
Chirality. 6:156-160
Chemoselective reduction of one isomer of the 1-menthylester of 1,3-oxathiolan-5-one-2-carboxylic acid produces a mixture of four lactol diastereomers from which the title compound was isolated after acylation. The isomeric purity and absolute stereo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71313990e74266af5a576432ed418f02
https://doi.org/10.1002/chir.530060217
https://doi.org/10.1002/chir.530060217
Autor:
Haolun Jin, Cimpoia Alex, Tibor Breining, Colleen A. Evans, Tarek S. Mansour, H. L. Allan Tse, M. Arshad Siddiqui, Dilip M. Dixit, Krzysztof Bednarski
Publikováno v:
Tetrahedron: Asymmetry. 4:2319-2322
Oxidative degradation of benzyloxymethylacetals derived from D-mannitol or L-ascorbic acid provides dioxolane intermediate 6 and 7 useful in the synthesis of all the stereoisomers of dioxolane nucleoside analogues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ab442c5a585fcbba49662aef167c018
https://doi.org/10.1016/s0957-4166(00)80092-0
https://doi.org/10.1016/s0957-4166(00)80092-0
Autor:
Martin Francis Jones, H. L. Allan Tse, Jeremy J. Payne, Tarek S. Mansour, Christopher Michael Donald Beels, P. Ravenscroft, Colleen A. Evans, David Cedric Humber, Haolun Jin, Ramsay Michael V J
Publikováno v:
Tetrahedron: Asymmetry. 4:211-214
TiCl4 and SnCl4 promote the formation of dioxolane nucleosides with racemization in the coupling of enantiomerically pure 2′-deoxy-3′oxaribosides with silylated N-acetylcytosine. The use of TMSOTf, TMSI or TiCl2(Oi-Pr)2 furnishes enantiomerically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf6cf1c47d1301e2825469310fcd2b53
https://doi.org/10.1016/s0957-4166(00)82340-x
https://doi.org/10.1016/s0957-4166(00)82340-x
Autor:
Colleen A. Evans, Haolun Jin, Dilip M. Dixit, Tarek S. Mansour, H. L. Allan Tse, Bernard Belleau
Publikováno v:
Tetrahedron Letters. 33:6949-6952
Enantiomerically pure 2′,3′-dideoxy-3′-oxacytidine nucleoside analogues were synthesized from L-ascorbic acid in eight steps and good overall yield.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd1cb26e5ac80848e259ce80c45160ea
https://doi.org/10.1016/s0040-4039(00)60903-6
https://doi.org/10.1016/s0040-4039(00)60903-6
Autor:
Haolun Jin, Ramsay Michael V J, Tarek S. Mansour, Colleen A. Evans, David Cedric Humber, Jeremy J. Payne, H. L. Allan Tse, Boulos Zacharie, Martin Francis Jones, Siddiqui Arshad M
Publikováno v:
Tetrahedron Letters. 33:4625-4628
The title compound has been prepared in enantiomerically pure form in four steps from (+)-thiolactic acid.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0500ad1ecc2b277de02a2ff2528084f
https://doi.org/10.1016/s0040-4039(00)61330-8
https://doi.org/10.1016/s0040-4039(00)61330-8
Autor:
H. L. Allan Tse, Christopher D. Beels, M. Arshad Siddiqui, Tarek S. Mansour, P. Ravenscroft, Michael D. Goodyear, Colleen A. Evans, Haolun Jin
Publikováno v:
The Journal of Organic Chemistry. 60:2621-2623
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b7cd0d2e748706444eb9303dfba0050
https://doi.org/10.1021/jo00113a050
https://doi.org/10.1021/jo00113a050
Publikováno v:
Journal of the American Chemical Society. 112:4552-4554
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afc5116204a7374c8137880c5fbb7368
https://doi.org/10.1021/ja00167a068
https://doi.org/10.1021/ja00167a068