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pro vyhledávání: '"H. Kim Bottomly"'
Autor:
Timur O. Yarovinsky, Hui-Chen Chen, H. Kim Bottomly, Anna M. Dittrich, Lan Xu, Sean Connolly, Patricia Ranney
Publikováno v:
ResearcherID
Signaling via innate immune mechanisms is considered pivotal for T cell-mediated responses to inhaled Ags. Furthermore, Th2 cells specific for one inhaled Ag can facilitate priming of naive T cells to unrelated new inhaled Ags, a process we call “T
Autor:
Hui-Chen Chen, H. Kim Bottomly, Anna M. Tan, Christina A. Herrick, Pierre Pochard, Stephanie C. Eisenbarth
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(7)
Allergic asthma is an inflammatory lung disease driven by Th2. We have shown that both Th1 and Th2 sensitization to inhaled OVA depend on the presence and concentration of LPS, where high concentrations (LPShi) induce Th1 and low concentrations (LPSl
Autor:
Christian Taube, Patricia Ranney, Hui-Chen Chen, Joachim Maxeiner, Valérie Staudt, Melanie Albrecht, Heinz-Gerd Hoymann, H. Kim Bottomly, Paula Preston-Hurlburt, Anna-Maria Dittrich
Publikováno v:
Journal of Allergy and Clinical Immunology. 128:168-177.e8
Background Our laboratory has shown that inhalational sensitization to new antigens is facilitated through an ongoing T H 2-polarized inflammation of the lung, a phenomenon we call "collateral priming." Objective We were interested to analyze whether
Publikováno v:
The Journal of Immunology. 115:648-652
Tissue tolerance was induced in neonatal rats by the intravenous injection of bone marrow cells from adult allogeneic rat donors. After 6 to 8 weeks, lymphoid cells from rats in which tolerance had been induced were tested for mixed lymphocyte reacti
Autor:
H. Kim Bottomly
Publikováno v:
Boston Globe (1/1/2006 to present); 1/17/2010, p1, 1p