Výsledky vyhledávání - "H. K. Webster"

Lack of a significant adverse cardiovascular effect of combined quinine and mefloquine therapy for uncomplicated malaria

Autor: Sasithon Pukrittayakamee, Paktiya Teja-Isavadharm, Timothy M. E. Davis, Wichai Supanaranond, Yupin Suputtamongkol, Nicholas J. White, H. K. Webster

Quinine dihydrochloride (10 mg salt/kg infused over one hour) and mefloquine (15 mg base/kg) were given simultaneously to 13 adults with uncomplicated falciparum malaria. Supine and standing blood pressures were recorded and the electrocardiogram mon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847f21f5db5d42d9091c15ee3c6098d9
https://doi.org/10.1016/s0035-9203(97)90528-9

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Immune cell activation in melioidosis: increased serum levels of interferon-gamma and soluble interleukin-2 receptors without change in soluble CD8 protein

Autor: H. K. Webster, Yupin Suputtamongkol, David A. B. Dance, Arthur E. Brown, W. Chaowagul, S. Kongchareon, N J White

Publikováno v: Europe PubMed Central

To evaluate immune cell activation in patients with melioidosis, serum samples were assayed for interferon-gamma (IFN-gamma), soluble interleukin-2 receptors (sIL-2R), and soluble CD8 protein (sCD8). Forty patients with sepsis (23 fatal cases, 17 sur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bb789e1bf3d65f144a319852f3b5f5
https://doi.org/10.1093/infdis/163.5.1145

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Halofantrine versus mefloquine in treatment of multidrug-resistant falciparum malaria

Autor: F O ter Kuile, G Dolan, L Phaipun, Nicholas J. White, Tan Chongsuphajaisiddhi, H. K. Webster, François Nosten, Christine Luxemburger, Michael D. Edstein

Publikováno v: Lancet, 341(8852), 1044-1049. Elsevier Limited

The continuing spread of multidrug resistance in Plasmodium falciparum malaria makes the search for alternative treatments ever more urgent. We have investigated the relative efficacy of halofantrine and mefloquine in two paired randomised trials on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae9afe6906ad91fb5c6ff8f7b5a828d
https://doi.org/10.1016/0140-6736(93)92409-m

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Arteether-induced brain injury in Macaca mulatta . I. The precerebellar nuclei: the lateral reticular nuclei, paramedian reticular nuclei, and perihypoglossal nuclei

Autor: D. E. Kyle, M. A. Vane, Young Gd, M. Gettayacamin, H K Webster, J. M. Petras, T. G. Brewer, K. D. Corcoran, James O. Peggins, R. A. Bauman

Publikováno v: Anatomy and Embryology. 201:383-397

Malaria poses a threat across several continents: Eurasia (Asia and parts of Eastern Europe), Africa, Central and South America. Bradley (1991) estimates human exposure at 2,073,000,000 with infection rates at 270,000,000, illnesses at 110,000,000, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fff254caa20944cfef93c4992702b0
https://doi.org/10.1007/s004290050326

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Lymphocyte activation after non-thermal trauma

Autor: Parinya Thavichaigarn, H. K. Webster, Prapassorn Kongcharoen, Narongchai Jiarakul, Kovit Pattanapanyasat, F C Pearce, William P. Wiesmann, Pricha Siritongtaworn, Pongsri Tongtawe, Kosol Yongvanitchit, C Dheeradhada, Douglas S. Walsh, Chulaluk Komoltri

Publikováno v: British Journal of Surgery. 87:223-230

BackgroundSevere injury causes immunological changes that may contribute to a poor outcome. Longitudinal characterization of lymphocyte response patterns may provide further insight into the basis of these immunological alterations.MethodsVenous bloo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7018615b6272104e322e85a4a0b1d44c
https://doi.org/10.1046/j.1365-2168.2000.01341.x

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The presence of the HLA class. II allele DPB1*0501 in ethnic Thais correlates with an enhanced vaccine-induced antibody response to a malaria sporozoite antigen

Autor: Daniel M. Gordon, H. K. Webster, Ekaraj Rungruang, Somboon Lekmak, Monchan Sirikong, Panpiman Longta, Dasnayanee Chandanayingyong, H. A. E. Stephens, Rapeepun Vangseratthana, Arthur Brown

Publikováno v: European Journal of Immunology. 25:3142-3147

In this study, we examined the correlation between the frequency of allelic variants of the class II human leukocyte antigen (HLA) DR, DQ and DP gene loci and the quantitative humoral immune response observed in 71 Thai volunteers, subsequent to vacc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c4e54e5eb462873e85cb32aefc346d
https://doi.org/10.1002/eji.1830251123

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Interleukin-10 Inhibits Tumor Necrosis Factor Production but Not Antigen-Specific Lymphoproliferation in Acute Plasmodium falciparum Malaria

Autor: H. K. Webster, Pangsri Tongtawe, Pravan Suntharasamai, May Ho, M. M. Sexton, Sornchai Looareesuwan

Publikováno v: Journal of Infectious Diseases. 172:838-844

In vivo interleukin (IL)-2, IL-4, IL-10, and interferon (IFN)-gamma production was measured at the mRNA transcript and protein levels in patients acutely infected with Plasmodium falciparum and during convalescence. Both IL-10 and IFN-gamma but not I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd28714b8a0a1aeafe53d475220b0a0
https://doi.org/10.1093/infdis/172.3.838

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Pharmacokinetic study of mefloquine in Thai children aged 5–12 years suffering from uncomplicated falciparum malaria treated with MSP or MSP plus primaquine

Autor: P. Attanath, V. Singhasivanon, Tan Chongsuphajaisiddhi, H. K. Webster, Arunee Sabchareon, Michael Edstein, I. Djaja Lika

Publikováno v: European Journal of Drug Metabolism and Pharmacokinetics. 19:27-32

A triple combination of mefloquine, sulfadoxine and pyrimethamine (MSP) was used with primaquine for the radical treatment of falciparum malaria in Thailand. Primaquine was reported to inhibit hepatic microsomal enzymes and drug metabolism in animal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e26966e7ca04dbb23970d89d424b81
https://doi.org/10.1007/bf03188819

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Malaria in Splenectomized Patients: Report of Four Cases and Review

Autor: H. K. Webster, Sornchai Looareesuwan, May Ho, Pravan Suntharasamai

Publikováno v: Clinical Infectious Diseases. 16:361-366

The spleen plays a central role in host defense against malaria in animals. Its role in human malaria is less well established. The spleen may contribute to protection against human malaria by mediating humoral or cellular immune responses or by clea

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https://doi.org/10.1093/clind/16.3.361

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Two-Color flow cytometric analysis of intraerythrocytic malaria parasite DNA and surface membrane-associated antigen in erythrocytes infected withPlasmodium falciparum

Autor: H. K. Webster, Kovit Pattanapanyasat, Rachanee Udomsangpetch

Publikováno v: Cytometry. 14:449-454

A method for fixation of Plasmodium falciparum infected erythrocytes and solubilization of the erythrocyte membrane with detergent was developed. This method was applied to two-color flow cytometric analysis of both intraerythrocytic (IE) malaria DNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55f99ff980f5f44edc9ee94175644dc
https://doi.org/10.1002/cyto.990140415

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