Zobrazeno 1 - 10
of 12
pro vyhledávání: '"H. K. Kumara"'
Publikováno v:
Bioorganic Chemistry. 87:252-264
A novel series of amino acids conjugated quinazolinone-Schiff's bases were synthesized and screened for their in vitro anticancer activity and validated by molecular docking and DNA binding studies. In the present investigations, compounds 32, 33, 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8942b910e3e5221b53f30c31cf843ac5
https://doi.org/10.1016/j.bioorg.2019.03.038
https://doi.org/10.1016/j.bioorg.2019.03.038
Publikováno v:
Archiv der PharmazieREFERENCES. 354(7)
The synthesis of a new small library of molecules containing bis-urea/thiourea pendants in lysine conjugated to three different heterocycles is described. The heterocycles used in this study have benzisoxazole/piperazine/piperidine units. After a det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a19c43ba88737a8d40c6aa9293b2cfd7
https://pubmed.ncbi.nlm.nih.gov/33728698
https://pubmed.ncbi.nlm.nih.gov/33728698
Autor:
H. K. Kumara, J. Shiva Kumar, Suhas Ramesh, Doddahindaiah M. Suyoga Vardhan, Dase Channe Gowda
Publikováno v:
Medicinal Chemistry Research. 27:1504-1516
The need for multiple drugs arises when the response to pharmacological inflection is complicated and the disease conditions get worsened. The treatment requires a common platform to which multiple drugs are linked and this methodology is proven to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e823b264fe056824f04d6af7558b27e5
https://doi.org/10.1007/s00044-018-2168-y
https://doi.org/10.1007/s00044-018-2168-y
Publikováno v:
Bioorganic chemistry. 90
A series of amino acids conjugated quinazolinone-Schiff's bases were synthesized and characterized by analytical and spectroscopic methods. All the synthesized analogues (8-43) and the intermediates (1-7) were screened for their in vitro antibacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1928974f675cd2960192326c54a8f9b4
https://pubmed.ncbi.nlm.nih.gov/31288137
https://pubmed.ncbi.nlm.nih.gov/31288137
Publikováno v:
Archiv der Pharmazie. 354:2000468
The synthesis of a new small library of molecules containing bis-urea/thiourea pendants in lysine conjugated to three different heterocycles is described. The heterocycles used in this study have benzisoxazole/piperazine/piperidine units. After a det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc60624c9319b79522fa8e88c76f27c5
https://doi.org/10.1002/ardp.202000468
https://doi.org/10.1002/ardp.202000468
Autor:
H. K. Kumara, D. Channe Gowda
Publikováno v:
International Journal of Peptide Research and Therapeutics. 23:259-267
A novel series of bisthiourea derivatives of four dipeptides consisting of Lys-Asp, lys-Asp, Lys-Trp and lys-Trp conjugated to 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazole were synthesized and characterized by physical method and spectroscopic data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31335041159d442f46f593c6c96c704d
https://doi.org/10.1007/s10989-016-9557-1
https://doi.org/10.1007/s10989-016-9557-1
Publikováno v:
Chemical Data Collections. 26:100343
Diabetes and tuberculosis are the chronic diseasea, highly affected mankind. Globally 422 million adults suffer from diabetes and two million deaths occur due to tuberculosis. A library of the mercaptooxadiazole analogs were synthesized by cyclizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea8207416ba2a2ad55185ea0a91efecc
https://doi.org/10.1016/j.cdc.2020.100343
https://doi.org/10.1016/j.cdc.2020.100343
Publikováno v:
RSC advances. 8(19)
The present investigation involves the synthesis and spectroscopic and biological activity studies of the bis-hydrazones of quinazolinones derived from aspartic acid and glutamic acid. The antioxidant activities of the compounds were evaluated using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338f1a66b58885a4669b78f072ab662e
https://pubmed.ncbi.nlm.nih.gov/35540474
https://pubmed.ncbi.nlm.nih.gov/35540474
Publikováno v:
Anti-inflammatoryanti-allergy agents in medicinal chemistry. 16(2)
Background: Studies on anti-inflammatory and antimicrobial agents remains a challenging and important area in medicinal chemistry research due to more toxic and rapid development of resistance against first effective drugs. In search of novel anti-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3abe5d2a7183070166b3dfe5af07d2a
https://pubmed.ncbi.nlm.nih.gov/28820051
https://pubmed.ncbi.nlm.nih.gov/28820051
Publikováno v:
Asian Journal of Research in Chemistry. 11:15
A facile, efficient and cost-effective protocol for the synthesis of symmetrically substituted azoarenes from nitroarenes by using readily available ammonium iodide as hydrogen donor and magnesium powder as catalyst at room temperature in methanol me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dcaccfc40d28b97088830d8be76b20e
https://doi.org/10.5958/0974-4150.2018.00004.4
https://doi.org/10.5958/0974-4150.2018.00004.4