Zobrazeno 1 - 10
of 263
pro vyhledávání: '"H. Jane Dyson"'
Autor:
Madison Malone, Ava Maeyama, Naomi Ogden, Kayla N. Perry, Andrew Kramer, Caleb Bates, Camryn Marble, Ryan Orlando, Amy Rausch, Caleb Smeraldi, Connor Lowey, Bronson Fees, H. Jane Dyson, Michael Dorrell, Heidi Kast-Woelbern, Ariane L. Jansma
Publikováno v:
Virus Research, Vol 348, Iss , Pp 199446- (2024)
The Human papillomavirus (HPV) causes tumors in part by hijacking the host cell cycle and forcing uncontrolled cellular division. While there are >200 genotypes of HPV, 15 are classified as high-risk and have been shown to transform infected cells an
Externí odkaz:
https://doaj.org/article/02f1bcb4f5b44a5cbcbc25e96d5bae9a
Publikováno v:
Biochemistry. 61:2709-2719
The C-terminal region of the tumor suppressor protein p53 contains three domains, nuclear localization signal (NLS), tetramerization domain (TET), and C-terminal regulatory domain (CTD), which are essential for p53 function. Characterization of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba774f0a57c83bb026e877d84748778
https://doi.org/10.1021/acs.biochem.2c00528
https://doi.org/10.1021/acs.biochem.2c00528
Publikováno v:
The Journal of Physical Chemistry B. 126:9539-9548
The earliest events in the folding of a protein are in general poorly understood. We used NMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cc770ea42eb5a0623b17025b3ba2ac
https://doi.org/10.1021/acs.jpcb.2c05592
https://doi.org/10.1021/acs.jpcb.2c05592
Publikováno v:
Nucleic Acids Research. 50:7147-7160
Protein dynamics involving higher-energy sparsely populated conformational substates are frequently critical for protein function. This study describes the dynamics of the homodimer (p50)2 of the p50 Rel homology region (RHR) of the transcription fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a09c5a5e112eb1d2dd83344a2d60046
https://doi.org/10.1093/nar/gkac535
https://doi.org/10.1093/nar/gkac535
Autor:
H. Jane Dyson, Peter E. Wright
Publikováno v:
Israel Journal of Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99196139648c7aaf37f4c8e909bc84ff
https://doi.org/10.1002/ijch.202300051
https://doi.org/10.1002/ijch.202300051
Publikováno v:
Biochemistry. 60:2663-2671
Conformational fluctuations from ground-state to sparsely populated but functionally important excited states play a key role in enzyme catalysis. For Escherichia coli dihydrofolate reductase (DHFR), the release of the product tetrahydrofolate (THF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccfb263095072eb94c693763dac4e9e8
https://doi.org/10.1021/acs.biochem.1c00461
https://doi.org/10.1021/acs.biochem.1c00461
Publikováno v:
Current Opinion in Chemical Biology. 73:102280
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::026b1901124f1bc896b07bd7e5b1a11f
https://doi.org/10.1016/j.cbpa.2023.102280
https://doi.org/10.1016/j.cbpa.2023.102280
Publikováno v:
The Journal of biological chemistry. 298(8)
Transthyretin (TTR) amyloidosis is associated with tissue deposition of TTR aggregates. TTR aggregation is initiated by dissociation of the native tetramer to form a monomeric intermediate, which locally unfolds and assembles into soluble oligomers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2981c364b3fb9973f5b54e5a4d1d55bf
https://pubmed.ncbi.nlm.nih.gov/35724960
https://pubmed.ncbi.nlm.nih.gov/35724960
Publikováno v:
Biochemistry
Wilms' tumor suppressor protein WT1 regulates the expression of multiple genes through binding of the Cys2-His2 zinc finger domain to promoter sites. WT1 has also been proposed to be involved in post-transcriptional regulation, by binding to RNA usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9fd8dfb7addef129d8243f26caec52
https://doi.org/10.1021/acs.biochem.0c00602
https://doi.org/10.1021/acs.biochem.0c00602
Publikováno v:
Biochemistry
Recognition of the epigenetic mark 5-methylcytosine (mC) at CpG sites in DNA has emerged as a novel function of many eukaryotic transcription factors (TFs). It remains unclear why the sequence specificity of these TFs differs for CpG-methylated motif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d86539f8927cf2673dea71429b0a46
https://doi.org/10.1021/acs.biochem.0c00253
https://doi.org/10.1021/acs.biochem.0c00253