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of 41
pro vyhledávání: '"H. J. Zeiler"'
It has been over 30 years since the first clinically important member of the quinolone class, nalidixic acid, was introduced into medical practice. The modification produced in the quinolone nucleus by introducing a fluorine at the 6-position led to
At a symposium in Wuppertal held on 26 September 1995, Dr. Karl-Georg Metzger was honored, on the occasion of his retirement, for his scientific contributions and involvement in antibacterial drug research and develop ment within Bayer AG. In 1963
Publikováno v:
Clinical and Experimental Immunology. 86:525-531
SUMMARY Ciprofloxacin (CIP) is a quinolone carboxylic acid derivative with a broad spectrum of antibacterial activity. CIP (0.1–30 μg/ml) enhanced DNA synthesis of mouse spleen cells and human peripheral blood lymphocytes (PBL) that had been activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbd01c8aa96fc82a03117305ef55932
https://doi.org/10.1111/j.1365-2249.1991.tb02964.x
https://doi.org/10.1111/j.1365-2249.1991.tb02964.x
Autor:
H.-J. Zeiler, J. T. Smith
Publikováno v:
Quinolone Antibacterials ISBN: 9783642803666
Lesher et al. (1962) showed that 7-chloro-1,4-dihydro-1-ethyl-4-oxoquinoline-3-carboxylic acid, referred to as compound (a), which was obtained as an impurity during the manufacture of chloroquine, possessed antibacterial activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01bf34c96f80ab49872524b4c50131e7
https://doi.org/10.1007/978-3-642-80364-2_1
https://doi.org/10.1007/978-3-642-80364-2_1
Publikováno v:
Antibacterial Therapy: Achievements, Problems and Future Perspectives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ac8356854d9c2f43cfc89d0bc492bc7
https://doi.org/10.1007/978-3-642-60803-2
https://doi.org/10.1007/978-3-642-60803-2
Akademický článek
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Autor:
K. Grohe, H. J. Zeiler
Publikováno v:
European Journal of Clinical Microbiology. 3:339-343
The antibacterial activity of ciprofloxacin (Bay o 9867) was compared with those of norfloxacin, nalidixic acid, trimethoprim-sulfamethoxazole, cefaclor, sisomicin and cefotaxime in in vitro and mouse protection studies. Approximately 300 clinical is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcdcef820018e1f737bcc8507100aa4
https://doi.org/10.1007/bf01977490
https://doi.org/10.1007/bf01977490
Publikováno v:
Infection. 16:S19-S23
A 200 mg oral dose of ciprofloxacin, norfloxacin or ofloxacin was administered to six healthy male volunteers in a three way cross-over study in order to examine the kinetics in humans in relation to the bactericidal activity in serum and urine. Seru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f938675d56cc2b9b5b384c8ac73139
https://doi.org/10.1007/bf01650502
https://doi.org/10.1007/bf01650502
Publikováno v:
Tetrahedron. 34:1979-1983
Zusammenfassung Wisanin, ein Inhaltsstoff von piper guineense (einer Pflanze, von der antibakterielle Wirksamkeiten berichtet sind), und andere Amide der 5 - (2 - Methoxy - 4,5 - methylendioxyphenyl) - 2,4 - pentadiensaure wurden—ausgehend von 3,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::810496f17172efedc53ac0e75719b0eb
https://doi.org/10.1016/0040-4020(78)80106-9
https://doi.org/10.1016/0040-4020(78)80106-9
Publikováno v:
Archives of Microbiology. 99:307-321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::748790cc257a5c495f78d8a1ce1c6c62
https://doi.org/10.1007/bf00696245
https://doi.org/10.1007/bf00696245