Zobrazeno 1 - 10
of 59
pro vyhledávání: '"H. J. T. Coelingh Bennink"'
Autor:
H. J. T. Coelingh Bennink
Publikováno v:
Climacteric. 26:168-168
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ca1938e4edd20c0b605344bd7e9bd0
https://doi.org/10.1080/13697137.2023.2167597
https://doi.org/10.1080/13697137.2023.2167597
Publikováno v:
Climacteric : the journal of the International Menopause Society. 11(sup1)
Currently, the synthetic steroid ethinylestradiol (EE) is the preferred estrogen in combined oral contraceptives. The aim of the present study was to evaluate the effectiveness of the natural steroid estetrol (E(4)) as an ovulation inhibitor in rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df4537c72035f9c46c2a8ac43af5584
https://pubmed.ncbi.nlm.nih.gov/28485646
https://pubmed.ncbi.nlm.nih.gov/28485646
Autor:
Yvette Zimmerman, M. Visser, H. J. T. Coelingh Bennink, Kristina Gemzell-Danielsson, J. B. Foidart, Carole Verhoeven
Publikováno v:
Climacteric : the journal of the International Menopause Society. 20(3)
Estetrol (E4) is a natural fetal estrogen. In this open-label, multiple-rising-dose study, the pharmacokinetic effects of E4 in postmenopausal women were investigated as a secondary objective.In total, 49 postmenopausal women were randomized to recei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4452aa030be8587222e776acf6a2164c
https://pubmed.ncbi.nlm.nih.gov/28267365
https://pubmed.ncbi.nlm.nih.gov/28267365
Publikováno v:
Climacteric. 11:69-72
This Appendix summarizes available data of maternal and fetal estetrol (E4) levels reported in the literature and obtained in a recent clinical study. The literature data were published mainly in t...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26cc799aab29cdcafd34a30396fbaa7
https://doi.org/10.1080/13697130802056321
https://doi.org/10.1080/13697130802056321
Publikováno v:
Climacteric. 11:64-68
In this Appendix, data are reported obtained by in vitro studies, performed with the human fetal steroid estetrol (E4). The studies have been executed by a commercial laboratory in Taiwan (MDS). Es...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c344b3fc961840b73919bdb3c67fba01
https://doi.org/10.1080/13697130802050340
https://doi.org/10.1080/13697130802050340
Publikováno v:
Climacteric. 11:15-21
To evaluate the efficacy of estetrol (E(4)) in alleviating hot flushes in an experimental animal model considered representative for menopausal vasomotor symptoms.Recording of the thermal responses in the tail skin of morphine-dependent ovariectomize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e6d52b32afa90b3a0272c2011d8c87
https://doi.org/10.1080/13697130701822807
https://doi.org/10.1080/13697130701822807
Publikováno v:
Climacteric, 11(S1), 22-28. Taylor and Francis Ltd.
Heegaard, A M, Holinka, C F, Kenemans, P & Coelingh Bennink, H J T 2008, ' Estrogenic uterovaginal effects of oral estetrol in the modified Allen-Doisy test ', Climacteric, vol. 11, no. S1, pp. 22-28 . https://doi.org/10.1080/13697130701842490
Heegaard, A M, Holinka, C F, Kenemans, P & Coelingh Bennink, H J T 2008, ' Estrogenic uterovaginal effects of oral estetrol in the modified Allen-Doisy test ', Climacteric, vol. 11, no. S1, pp. 22-28 . https://doi.org/10.1080/13697130701842490
Objective To evaluate the effect of estetrol (E4) on vaginal cornification and uterine wet weight in the ovariectomized rat.Methods Adult female rats served as experimental animals. Six groups of ovariectomized rats (eight per group) were treated ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a97985c39392b07264ea134749a3492
https://doi.org/10.1080/13697130701842490
https://doi.org/10.1080/13697130701842490
Autor:
M. Visser, A.-M. Heegaard, Claus Christiansen, H. J. T. Coelingh Bennink, Christian Franz Holinka
Publikováno v:
Climacteric. 11:2-14
To measure the oral bioavailability of estetrol (E(4)) in rats relative to its subcutaneous administration and to test the bone-sparing effect of oral E(4) compared to that of ethinylestradiol (EE).In the bioavailability study, E(4) was administered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbdc740cb88a6166571b49ce2c0b95e
https://doi.org/10.1080/13697130701798692
https://doi.org/10.1080/13697130701798692
Publikováno v:
Climacteric. 11:31-40
To evaluate the safety, tolerability, pharmacokinetics and effect on gonadotropins of a single escalating dose of estetrol (E(4)).A first-in-human study with E(4) was performed in healthy early postmenopausal women. Four single doses of 0.1, 1, 10 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422b4f0af9f86a537dc97ecaf37f0097
https://doi.org/10.1080/13697130802056511
https://doi.org/10.1080/13697130802056511
