Zobrazeno 1 - 10
of 184
pro vyhledávání: '"H. J. Schümann"'
Autor:
H. J. Schümann
Publikováno v:
Ciba Foundation Symposium-Adrenergic Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c737536c3e288f50da43c19f7be4bc3c
https://doi.org/10.1002/9780470719206.ch2
https://doi.org/10.1002/9780470719206.ch2
Autor:
G.J. Molderings, H.-J. Schümann
Publikováno v:
Pharmacology. 39:373-382
In guinea-pig aorta phenylephrine and noradrenaline induced concentration-dependent contractions when beta-adrenoceptors were blocked. The contractile response to phenylephrine was amplified by previous application of subthreshold concentrations of 5
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 302:333-336
In isolated, electrically driven right auricular strips of the human heart the inotropic effect of phenylephrine was studied. 1. First, the influence of the driving rate on the tension developed (i.e., the frequency-force relationship) was determined
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 318:330-335
The influence of sympathomimetic α- and β-agonists on calcium-dependent slow action potential (SAP) and force of contraction were analyzed in the partially depolarized rabbit papillary muscle. 1. The effects of phenylephrine (3×10−6 mol/l) on SA
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 287:61-72
On the isolated rabbit papillary muscle experiments were carried out to determine whether the positive inotropic effects mediated by α- and by β-adrenoceptors are brought about by different mechanisms or not.—For this reason the influence of temp
Autor:
H. J. Schümann, M. Endoh
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 287:377-389
Under the conditions of different stimulation frequencies the inotropic effects of the α-adrenoceptor stimulating agents, methoxamine, naphazoline and oxymetazoline were studied on the isolated rabbit papillary muscle. 1. On the papillary muscle sti
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 315:85-88
The beta-sympathomimetic effect of prenalterol was investigated on the electrically driven left atrium as well as on the tracheal chain of the guinea pig. 1. On the atrium driven at 2 Hz prenalterol caused a positive inotropic effect with a pD2-value
Publikováno v:
Agents and Actions. 4:217-221
The histamine blocking properties of burimamide and promethazine were determined on heart rate and contractility of the right and left atrium of the guinea-pig. (1) The positive chronotropic effect in spontaneously beating guinea-pig atria was compet
Publikováno v:
Agents and Actions. 7:1-12
On guinea-pig heart we investigated whether cyclic AMP serves as a messenger for H1 - and/or H2-mediated responses to histamine. (1) On papillary muscle histamine elicited positive inotropic responses which were antagonized by burimamide but not by p