Zobrazeno 1 - 10
of 29
pro vyhledávání: '"H. J. Obert"'
Autor:
H.-J. Obert, P. H. Hofschneider
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 110:1766-1769
During the last two years, 80 patients with definite chronic rheumatoid arthritis were treated with interferon-gamma. Considerable improvement in the clinical picture occurred in 58, with pain decreasing rapidly and lastingly or even disappearing. Ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da4b78a2cc7298d7df480b9a2d9c6bfe
https://doi.org/10.1055/s-2008-1069083
https://doi.org/10.1055/s-2008-1069083
Autor:
H.-J. Obert, D. Pöhlau
Die Therapie der Multiplen Sklerose stellt sich zunehmend differenzierter dar. Unterschiedliche Wirkstoffe sind entwickelt und klinisch untersucht, nicht alle halten der Prüfung stand. Die Behandlung mit Beta-Interferon ist jedoch inzwischen etablie
Autor:
D. Richter, S. Schmid, P. H. Hofschneider, H. E. Stierle, Klaus Krüger, S. Herzig, W. Reemtsen, W. Gaus, U. Winter, H. D. Waller, W. H. Boesken, B. Brölz, J. R. Kalden, H. Warnatz, K. Wilms, A. K. von Kalle, C. Weyand, I. O. Auer, S. Meske, C. Gärtner, D. Brackertz, U. Botzenhardt, C. Stetter, Volker Diehl, M. Schattenkirchner, J. G. Saal, F. Strobel, H. J. Obert, K. Machalke, Hans-Hartmut Peter, T. Stolzenburg, R. Sprekeler, J. Goronzy, E. M. Lemmel, G. Lemm, C. Papst
Publikováno v:
Rheumatology International. 12:175-185
The controlled clinical trial reported here is part of a multicenter clinical and basic research project, sponsored by the German Federal Minister of Science and Technology, directed by a standing commission of the president of the Max-Planck-Gesells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a033a2e6e43cfb2b236fd3da71a338e
https://doi.org/10.1007/bf00302149
https://doi.org/10.1007/bf00302149
Autor:
H.-J. Obert, J. Brzoska
Publikováno v:
Genital Papillomavirus Infections ISBN: 9783642757259
Interferons (IFN) possess antiviral and antiproliferative properties and modulate cell differentiation and immune functions (Stanton et al. 1987; Gastl and Huber 1988). The antiviral, antiproliferative, and cell-differentiating effectiveness increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8605187b42e5fdc69c6d55c84ebe3cf1
https://doi.org/10.1007/978-3-642-75723-5_28
https://doi.org/10.1007/978-3-642-75723-5_28
Publikováno v:
Zeitschrift fur Rheumatologie. 49(1)
Results of a large therapeutic trial of interferon-gamma in patients with rheumatoid arthritis (RA) are described. Of 110 RA-patients enrolled in this clinical trial, 46 were treated with interferon-gamma for 12 months. During the treatment period, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27c390eac0c271f3812582b0926441c2
https://pubmed.ncbi.nlm.nih.gov/2109438
https://pubmed.ncbi.nlm.nih.gov/2109438
Autor:
E. M. Lemmel, D. Brackertz, M. Franke, W. Gaus, P. W. Hartl, K. Machalke, H. Mielke, H. J. Obert, H. H. Peter, J. Sieper, R. Sprekeler, H. Stierle
Publikováno v:
Rheumatology International. 8:87-93
In a multicenter placebo-controlled double-blind randomized clinical study, 91 patients with rheumatoid arthritis were given 28 days' treatment with recombinant interferon-gamma (50 micrograms daily for 20 days, then 50 micrograms each second day up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b384c2f1d35a4be03ad656c3acb2dfd4
https://doi.org/10.1007/bf00271840
https://doi.org/10.1007/bf00271840
Autor:
J, Brzoska, H J, Obert
Publikováno v:
Arzneimittel-Forschung. 37(12)
A survey is given of the immunomodulatory effects of interferon gamma (IFN-gamma) in inflammation. IFN-gamma influences the activity of macrophages, granulocytes, B-lymphocytes, suppressor-T-lymphocytes and natural killer cells as well as the product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad2be8e0437d3b6096eba244feeb8864
https://pubmed.ncbi.nlm.nih.gov/2835054
https://pubmed.ncbi.nlm.nih.gov/2835054
[Interferon gamma in the treatment of chronic polyarthritis. Long-term therapy in clinical practice]
Autor:
H J, Obert, J F, Brzoska
Publikováno v:
Arzneimittel-Forschung. 39(7)
Efficacy and practicability of a defined dosage scheme for interferon gamma was proved during one year's treatment in patients with rheumatoid arthritis. Interferon gamma was well tolerated. It was effective in improving blood sedimentation rate, ane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0788c659c06207b20d1c9d12c2c73e17
https://pubmed.ncbi.nlm.nih.gov/2506869
https://pubmed.ncbi.nlm.nih.gov/2506869
Autor:
H J, Obert, J, Brzoska
Publikováno v:
Arzneimittel-Forschung. 36(10)
The paper gives a survey of the studies with interferon-gamma and the actual status of the clinical trials with this substance concerning rheumatoid arthritis (RA). About 60% of the patients with RA respond to the therapy. In the initial therapy whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db1a18b7f278deeff20a7f1ceebbe30f
https://pubmed.ncbi.nlm.nih.gov/3101709
https://pubmed.ncbi.nlm.nih.gov/3101709
Autor:
J. Lohmeyer, H. Pralle, E. P. Rieber, H. Feucht, G. Riethmüller, M. Hadam, W. L. Gross, A. Rucks, E. Heidemann, K. Cantell, D. Niethammer, H.-J. Obert, U. Reichmann, H. Schmidt, J. Treuner, K. Wilms, R. Stahn, H.-Å. Fabricius, E. Köttgen, W. Brummer, R. Fetta, R. E. Schopf, J. Mattar, W. Meyenburg, E.-M. Lemmel, H. Link, U. Reinhard, H. D. Waller, B. Maisch, E. Mayer, K. Kochsiek, H. A. Katus, M. Ruland, J. Hurrell, E. Haber, W. Kübler
Publikováno v:
Verhandlungen der Deutschen Gesellschaft für innere Medizin ISBN: 9783807003320
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d8a491989772f3e2a70faa2a651f9b7
https://doi.org/10.1007/978-3-642-47093-6_13
https://doi.org/10.1007/978-3-642-47093-6_13