Zobrazeno 1 - 10
of 210
pro vyhledávání: '"H. J. Machulla"'
Autor:
H.-J. Machulla, C. Solbach
Publikováno v:
Applied Radiation and Isotopes. 65:1345-1349
The preparation of [11C]chloroform by direct chlorination of [11C]methane using gaseous chlorine by variation of temperature and reaction time (inert gas flow) without catalyst support for the online production of [11C]diazomethane in a flow-through
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 270:313-318
Fluorodehalogenation reactions were used to prepare 6-[18F]fluoroveratraldehyde. The synthesis of 6-[18F]fluoroveratraldehyde is the first step in the multi-step synthesis of the clinically important tracer 6-[18F]fluoro-L-dopa. In the literature yie
Publikováno v:
Radiochimica Acta. 94:143-146
Summary As a clinically well established PET tracer, 6-[18F]fluoro-L-dopa is prepared by a multi-step synthesis if [18F]fluoride is to be used for labelling. The [18F] label is introduced in the first step, i.e. 6-[18F]fluoroveratraldehyde is prepare
Autor:
H.-J. Machulla, H. Bihl
Publikováno v:
Der Nuklearmediziner. 28:47-55
Publikováno v:
Applied Radiation and Isotopes. 58:679-683
Electrochemical fluorination of various monosubstituted aromatic compounds was performed with [18F]fluoride using potentiostatic anodic oxidation on platinum electrodes in an undivided cell in acetonitrile with a mixture of Et3N·3HF/Et3N·HCl as ele
Publikováno v:
Journal of Lipid Research, Vol 25, Iss 10, Pp 1102-1108 (1984)
The omega-(p-iodo-phenyl)-pentadecanoic acid (I-PPA) has been used successfully for the investigation of the cardiac metabolic activity and for the imaging of the myocardium (Machulla, H. J., M. Marsmann, and K. Dutschka. 1980. Eur. J. Nucl. Med. 5:
Externí odkaz:
https://doaj.org/article/54c2ebbe80114c1d8cb97b3c05a6b60d
Publikováno v:
Nuklearmedizin. Nuclear medicine. 52(5)
Publikováno v:
Der Nervenarzt. 67:721-729
Changes in regional cerebral blood flow (rCBF) during experimentally modified psychological activation can be measured using radioactive ligands with positron emission tomography (PET) and using magnetic resonance principles with functional magnetic
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 70(8)
A rapid and efficient n.c.a. radiosynthesis of 6-[(11)C]methyldopamine ([(11)C]MeDA) using the Stille cross-coupling reaction as a key step was developed. The labeling conditions for the formation of the intermediate compound (protected [(11)C]MeDA,
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 254:409-411
18F-labeling of aromatic compounds normally is achieved by electrophilic substitution. In that case [18F]fluoride cannot be applied although it is produced very efficiently at medical cyclotrons. By the use of electrochemical methods, however, benzen