Zobrazeno 1 - 10
of 177
pro vyhledávání: '"H. J. J. Pabon"'
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 85:1233-1250
The enzyme specificity in the biosynthesis of prostaglandins has been investigated by incubation of a particulate fraction of sheep vesicular glands with ω6 tri- and tetraenoic C18 - C22 fatty acids and isomers of ω6 eicosatrienoic acid (20: 3 ω6)
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 94:257-261
Various 2-substituted all-cis-8,11,14-eicosatrienoic acids have been prepared via coupling of all-cis-6,9,12-octadecatrienyl methanesulfonate with diethyl malonate, substituted diethyl malonates, ethyl cyanoacetate or ethyl 2-cyanohexanoate. The subs
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 82:1015-1025
The usefulness of hexa-2,5-diyn-1-ol as an intermediate in the synthesis of arachidonic acid, poly-yn alcohols and docosa-4,7,10,13,16,19-hexaynoic acid is demonstrated. Difficulties in the partial reduction of the latter product to the corresponding
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 94:262-273
The synthesis of the following groups of acids is described: (a) 3-Methyl-c-2,c-8,c-11,c-14-, and 3-methyl-t-2,c-8,c-11,c-14-eicosatetraenoic acid and 3-methyl-c-8,c-11,c-14-eicosatrienoic acid, (b) c-8,c-11,c-14-eicosatrien-5-ynoic acid, (c) c-2,3-m
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 87:461-480
All-cis 8,11,14-octadecatrienoic-(18:3 ω4), nonadecatrienoic-(19:3 ω5), heneicosatrienoic-(21:3 ω7), docosatrienoic-(22:3 ω8) and 5,8,11,14-nonadecatetraenoic-(19:4 ω5) and heneicosatetraenoic-(21:4 ω7) acid were synthesized. These fatty acids
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 90:943-960
A series of polyunsaturated fatty acids has been tested on essential fatty acid activity and as precursors of prostaglandins. It was confirmed that biological activity of all-cis 8,11,14-trienoates and 5,8,11,14-tetraenoates is restricted to acids wi
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 99:132-137
For studies into the relationship between their physical properties and chemical structure, several polyunsaturated fatty acids related to (Z,Z,Z)-6,9,12-octadecatrienoic acid and (Z,Z,Z)-8,11,14-eicosatrienoic acid were synthesized. Methyl (E,Z,Z)-2
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 90:961-973
Hydrogenation of skipped polyynoic acids and esters over Lindlar's catalyst in the presence of quinoline proceeds with optimum results in light petroleum, ethyl acetate, or acetone at room temperature, yielding the corresponding all-cis polyenoic com
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 89:1043-1053
By the reaction of 3-(3′-acetoxyoctyl)-2-(6′-carboxyhexyl)-2-cyclopenten-1-one, the acetoxy derivative of Prostaglandin E1 - 237 (PGE1 - 237), with N-bromosuccinimide in carbon tetrachloride, followed by treatment of the reaction product with sil
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 96:172-175
On the basis of trans-2-hexene-1,6-diol and trans-2-octenol, both obtained by trans reduction of their acetylenic precursors with sodium in liquid ammonia, trans-5-eicosene-8,1 1,14-triynoic acid and trans- 14-eicosene-5,8,11-triynoic acid were built