Zobrazeno 1 - 10
of 80
pro vyhledávání: '"H. J. Gould."'
Autor:
D. Ferastraoaru, H. J. Bax, C. Bergmann, M. Capron, M. Castells, D. Dombrowicz, E. Fiebiger, H. J. Gould, K. Hartmann, U. Jappe, G. Jordakieva, D. H. Josephs, F. Levi-Schaffer, V. Mahler, A. Poli, D. Rosenstreich, F. Roth-Walter, M. Shamji, E. H. Steveling-Klein, M. C. Turner, E. Untersmayr, S. N. Karagiannis, E. Jensen-Jarolim
Publikováno v:
Clinical and Translational Allergy, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Elevated serum IgE levels are associated with allergic disorders, parasitosis and specific immunologic abnormalities. In addition, epidemiological and mechanistic evidence indicates an association between IgE-mediated immune surveillance and
Externí odkaz:
https://doaj.org/article/36a0b020323b456eaa5ab6efccfb84e4
Publikováno v:
Clinical and Experimental Allergy
Background The interaction between IgE and allergen is a key event at the initiation of an allergic response, and its characteristics have substantial effects on the clinical manifestation. Despite this, the molecular details of the interaction betwe
Publikováno v:
The Journal of Immunology. 150:2372-2382
The low affinity receptor for IgE (Fc epsilon RII/CD23) is a type II integral membrane protein with an extracellular C-terminal region homologous to C-type animal lectins. Immediately adjacent to this lectin homology region is a sequence that is pred
Autor:
C. G. Cusick, H. J. Gould
Publikováno v:
The Journal of Comparative Neurology. 292:83-102
The goal of this study was to determine whether somatosensory thalamic nuclei other than the ventroposterior nucleus proper (VP) have connections with area 3b of the postcentral cortex in squirrel monkeys. Small injections of the anatomical tracers w
Publikováno v:
Brain topography. 14(2)
The purpose of the present study was to investigate auditory stimulus feature processing and how neural generators might differ among the mismatch negativity (MMN) responses to intensity, frequency, and duration deviant stimuli. Data collected from 7
Publikováno v:
European journal of immunology. 31(12)
The location of IgE synthesis has been a longstanding controversy, with previous evidence favoring either the mucosa or lymphoid tissue in the region of allergen entry. The evidence for IgE synthesis in mucosal tissues has always been circumstantial.
Autor:
J M, McDonnell, R, Calvert, R L, Beavil, A J, Beavil, A J, Henry, B J, Sutton, H J, Gould, D, Cowburn
Publikováno v:
Nature structural biology. 8(5)
The stability of the complex between IgE and its high-affinity receptor, FcepsilonRI, on mast cells is a critical factor in the allergic response. The long half-life of the complex of IgE bound to this receptor in situ ( approximately 2 weeks, compar
Publikováno v:
Journal of the American Academy of Audiology. 11(8)
Distortion product otoacoustic emissions (DPOAEs) evoked by single tone pairs and three simultaneous tone pairs were recorded in 60 normal-hearing adult ears. The purpose was to replicate a previous study using the commercially available probe assemb
Publikováno v:
Biochemistry. 39(25)
Immunoglobulin E (IgE) exhibits a uniquely high affinity for its receptor, FcepsilonRI, on the surface of mast cells and basophils. Previous work has implicated the third domain of the constant region of the epsilon-heavy chain (Cepsilon3) in binding
Autor:
H J, Gould, G A, Mackay, S N, Karagiannis, C M, O'Toole, P J, Marsh, B E, Daniel, L R, Coney, V R, Zurawski, M, Joseph, M, Capron, M, Gilbert, G F, Murphy, R, Korngold
Publikováno v:
European journal of immunology. 29(11)
Allergic reactions are mediated by IgE antibodies bound to high-affinity receptors on mast cells in peripheral tissues and are characterized by their immediacy and hypersensitivity. These properties could also be advantageous in immunotherapy against