Zobrazeno 1 - 10
of 26
pro vyhledávání: '"H. J. Fehling"'
Autor:
H J Fehling, W van Ewijk, J L Pasquali, C Waltzinger, M Le Meur, P Gerlinger, C Benoist, D Mathis
Publikováno v:
The Journal of Immunology. 144:2865-2874
We report the creation and characterization of several transgenic mouse lines that carry genes coding for the Ak alpha or Ak beta MHC class II (or Ia) molecules. In all these lines, the transgenes are expressed at the RNA and protein level with corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c0c5a2bbe47018f46273ebc63e17cf
https://doi.org/10.4049/jimmunol.144.8.2865
https://doi.org/10.4049/jimmunol.144.8.2865
Autor:
A. Zwinderman, Hansjörg Schild, Birgitt Schönfisch, C. Laplace, Markus Schirle, Tobias P. Dick, M. Kraft, H. J. Fehling, Johannes Müller, René E. M. Toes, Stefan Stevanovic, Niels Emmerich, Alexander K. Nussbaum, S. Degermann, C. Schmid, Hans-Georg Rammensee
Publikováno v:
The Journal of Experimental Medicine
Proteasomes are the main proteases responsible for cytosolic protein degradation and the production of major histocompatibility complex class I ligands. Incorporation of the interferon γ–inducible subunits low molecular weight protein (LMP)-2, LMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2443c414d84b759f5498ee7c2e0cb6
https://pubmed.ncbi.nlm.nih.gov/11435468
https://pubmed.ncbi.nlm.nih.gov/11435468
Publikováno v:
European journal of immunology. 29(6)
Most natural killer T (NKT) cells express a highly skewed alphabeta TCR repertoire, consisting of an invariant V alpha14-J alpha281 chain paired preferentially with a polyclonal Vbeta8.2 chain. This repertoire is positively selected by the monomorphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64e45c680f04b38dd33f3db103411bf6
https://pubmed.ncbi.nlm.nih.gov/10382759
https://pubmed.ncbi.nlm.nih.gov/10382759
Publikováno v:
Advances in immunology. 71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7c728f222fedf9ca3fb926933235a37
https://pubmed.ncbi.nlm.nih.gov/9917910
https://pubmed.ncbi.nlm.nih.gov/9917910
Publikováno v:
Immunity. 8(6)
Expression of a TCRgamma transgene in RAG-1-/- mice resulted in the development of a limited number of CD4+CD8+ (DP) thymocytes. In vivo treatments with anti-TCRgamma antibody enhanced the number of DP thymocytes, demonstrating that TCRgamma chains w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6613c44958489b1db8caaa0e1e1d70a
https://pubmed.ncbi.nlm.nih.gov/9655485
https://pubmed.ncbi.nlm.nih.gov/9655485
Autor:
H J, Fehling, B M, Iritani, A, Krotkova, K A, Forbush, C, Laplace, R M, Perlmutter, H, von Boehmer
Publikováno v:
Immunity. 6(6)
Mice deficient for the pre-TCR alpha (pT alpha) chain cannot form a pre-T cell receptor (TCR) and exhibit a severe defect in early T cell development, characterized by lack of "beta selection" and impaired generation of double-positive (DP) thymocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a066046ac660c2d7dbede2d591fccd83
https://pubmed.ncbi.nlm.nih.gov/9208843
https://pubmed.ncbi.nlm.nih.gov/9208843
Publikováno v:
Immunity. 5(4)
In peripheral lymphoid tissues of TCR transgenic mice that express the nominal antigen (HY peptide plus H-2Db MHC) recognized by the transgenic TCR, there exist unusual CD4-CD8- and CD4-CD8low cells bearing the transgenic TCR. Here we show that, unli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::490e3e856665fed57f2299ee630420d9
https://pubmed.ncbi.nlm.nih.gov/8885867
https://pubmed.ncbi.nlm.nih.gov/8885867
Publikováno v:
Nature. 375(6534)
In T-cell precursors, the T-cell-receptor beta chain is expressed before the T-cell-receptor alpha chain and is sufficient to advance T-cell development in the absence of T-cell receptor alpha chains. In immature T cells, the T-cell-receptor beta pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1036fa46729306c2a506b22feff316c
https://pubmed.ncbi.nlm.nih.gov/7596413
https://pubmed.ncbi.nlm.nih.gov/7596413
Akademický článek
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Publikováno v:
Molecular and Cellular Biology. 8:3975-3987
Transcription of major histocompatibility complex class II genes is elaborately regulated. Mouse class II genes are transcribed primarily in B cells, peripheral macrophages and interdigitating cells, and thymic cortical and medullary cells. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e79a7148e0bd792f70df07781784b1b
https://doi.org/10.1128/mcb.8.10.3975-3987.1988
https://doi.org/10.1128/mcb.8.10.3975-3987.1988