Zobrazeno 1 - 10
of 63
pro vyhledávání: '"H. J. Armbrecht"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1822(5):650-656
The senescence accelerated mouse (SAMP8) is a spontaneous animal model of overproduction of amyloid precursor protein (APP) and oxidative damage. It develops early memory disturbances and changes in the blood–brain barrier resulting in decreased ef
Publikováno v:
Current Pharmaceutical Design. 18:1123-1130
The senescence accelerate mouse P8 (SAMP8) is an excellent model of early learning and memory problems. A number of studies have shown that it has cholinergic deficits, oxidative damage, alterations in membrane lipids and circadian rhythm disturbance
Autor:
Martin Y. H. Zhang, Renata C. Pereira, Farzana Perwad, H. J. Armbrecht, Anthony A. Portale, Daniel Ranch
Publikováno v:
Endocrinology. 153:1806-1816
The X-linked hypophosphatemic (Hyp) mouse carries a loss-of-function mutation in the phex gene and is characterized by hypophosphatemia due to renal phosphate (Pi) wasting, inappropriately suppressed 1,25-dihydroxyvitamin D [1,25(OH)2D] production, a
Autor:
William A. Banks, R. T. Kevorkian, H. J. Armbrecht, Akbar M. Siddiqui, Angela D. Mazza, M. J. Kim, Matthew T. Haren, Michael Green, Vijaya B. Kumar, M. J. Haas, John E. Morley
Publikováno v:
International Journal of Andrology. 34:55-68
Testosterone regulates energy metabolism and skeletal muscle mass in males, but the molecular mechanisms are not fully understood. This study investigated the response of skeletal muscle to castration and testosterone replacement in 8-week-old male m
Publikováno v:
Journal of Biological Chemistry. 284:11059-11069
Although parathyroid hormone (PTH) induces 25-hydroxyvitamin D(3) (25(OH)D(3)) 1alpha-hydroxylase (1alpha(OH)ase) under hypocalcemic conditions, previous studies showed that calcitonin, not PTH, has an important role in the maintenance of serum 1,25-
Autor:
William A. Banks, Susan A. Farr, Ping Patrick, Akbar M. Siddiqui, Gul N. Shah, H. J. Armbrecht, Michael Green, Vijaya B. Kumar, John E. Morley
Publikováno v:
Journal of Alzheimer's disease : JAD. 46(2)
The senescence-accelerated mouse (SAMP8) strain exhibits an age-related decrease in memory accompanied by an increase in hippocampal amyloid-β protein precursor (AβPP) and amyloid-β peptide (Aβ). We have shown that administration of an antisense
Publikováno v:
Archives of Biochemistry and Biophysics. 420:194-200
The capacity of rats and humans to adapt to low dietary Ca by increasing intestinal Ca absorption declines with age. The intestinal calbindin-D-9k protein (calbindin) is thought to play a role in the transcellular transport of Ca across the mammalian
Publikováno v:
American Journal of Physiology-Renal Physiology. 284:F1032-F1036
The capacity of parathyroid hormone (PTH) to stimulate renal 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] production declines with age in the rat. The purpose of these studies was to determine whether this decline is due to a decreased capacity of PTH to i
Publikováno v:
Digestive Diseases and Sciences. 47:2831-2838
The purpose of this study was to develop an organ culture system for adult and old rat small intestine that is responsive to vitamin D. Explants from F344 rats were cultured on Millipore tissue culture inserts placed in 6-well dishes at a temperature
Publikováno v:
Journal of Endocrinology. 169:145-151
Non-transformed rat intestinal epithelial cell (IEC) lines were used to study the action of 1,25-dihydroxyvitamin D(3) (1,25(OH)2D) in the intestine. The capacity of 1,25(OH)2D to increase the expression of the cytochrome P450 component of the vitami