Zobrazeno 1 - 10 of 56 pro vyhledávání: '"H. Irons"'
1
Akademický článek
Intracerebral Xenotransplantation of GFP Mouse Bone Marrow Stromal Cells in Intact and Stroke Rat Brain: Graft Survival and Immunologic Response
Autor: H. Irons M.D., Ph.D., J. G. Lind, C. G. Wakade, G. Yu, M. Hadman, J. Carroll, D. C. Hess, Cesar V. Borlongan
Publikováno v: Cell Transplantation, Vol 13 (2004)
The present study characterized survival and immunologic response of bone marrow stromal cells (BMSCs) following transplantation into intact and stroke brains. In the first study, intrastriatal transplantation of BMSC (60,000 in 3 μl) or vehicle was
Externí odkaz: https://doaj.org/article/bbf4585b49b74a1a860140968f20fa43
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2
Akademický článek
Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology
Autor: Elizabeth A Bearce, Zoe H Irons, Johnathan R O'Hara-Smith, Colin J Kuhns, Sophie I Fisher, William E Crow, Daniel T Grimes
Publikováno v: eLife, Vol 11 (2022)
The spine provides structure and support to the body, yet how it develops its characteristic morphology as the organism grows is little understood. This is underscored by the commonality of conditions in which the spine curves abnormally such as scol
Externí odkaz: https://doaj.org/article/43f7a1eac97d4b55a49013a64399c982
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3
Akademický článek
Building the cytokinetic contractile ring in an early embryo: Initiation as clusters of myosin II, anillin and septin, and visualization of a septin filament network.
Autor: Chelsea Garno, Zoe H Irons, Courtney M Gamache, Quenelle McKim, Gabriela Reyes, Xufeng Wu, Charles B Shuster, John H Henson
Publikováno v: PLoS ONE, Vol 16, Iss 12, p e0252845 (2021)
The cytokinetic contractile ring (CR) was first described some 50 years ago, however our understanding of the assembly and structure of the animal cell CR remains incomplete. We recently reported that mature CRs in sea urchin embryos contain myosin I
Externí odkaz: https://doaj.org/article/4a6d5b48ff934394b455180e16f66ed7
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5
Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish
Autor: Gabriel Luna-Arvizu, Daniel T. Grimes, Victoria L. Patterson, Zoe H. Irons, Jodi Schottenfeld-Roames, Rebecca D. Burdine
Publikováno v: Developmental Biology. 459:79-86
Building a left-right (L-R) asymmetric organ requires asymmetric information. This comes from various sources, including asymmetries in embryo-scale genetic cascades (including the left-sided Nodal cascade), organ-intrinsic mechanical forces, and cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bc17a60151223f9983472b4b778536
https://doi.org/10.1016/j.ydbio.2019.11.012
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6
Biallelic DAW1 variants cause a motile ciliopathy characterized by laterality defects and subtle ciliary beating abnormalities
Autor: Joseph S. Leslie, Rim Hjeij, Asaf Vivante, Elizabeth A. Bearce, Laura Dyer, Jiaolong Wang, Lettie Rawlins, Joanna Kennedy, Nishanka Ubeyratna, James Fasham, Zoe H. Irons, Samuel B. Craig, Julia Koenig, Sebastian George, Ben Pode-Shakked, Yoav Bolkier, Ortal Barel, Shrikant Mane, Kathrine K. Frederiksen, Olivia Wenger, Ethan Scott, Harold E. Cross, Esben Lorentzen, Dominic P. Norris, Yair Anikster, Heymut Omran, Daniel T. Grimes, Andrew H. Crosby, Emma L. Baple
Publikováno v: Leslie, J S, Hjeij, R, Vivante, A, Bearce, E A, Dyer, L, Wang, J, Rawlins, L, Kennedy, J, Ubeyratna, N, Fasham, J, Irons, Z H, Craig, S B, Koenig, J, George, S, Pode-Shakked, B, Bolkier, Y, Barel, O, Mane, S, Frederiksen, K K, Wenger, O, Scott, E, Cross, H E, Lorentzen, E, Norris, D P, Anikster, Y, Omran, H, Grimes, D T, Crosby, A H & Baple, E L 2022, ' Biallelic DAW1 variants cause a motile ciliopathy characterized by laterality defects and subtle ciliary beating abnormalities ', Genetics in Medicine, vol. 24, no. 11, pp. 2249-2261 . https://doi.org/10.1016/j.gim.2022.07.019
Purpose: The clinical spectrum of motile ciliopathies includes laterality defects, hydrocephalus, and infertility as well as primary ciliary dyskinesia when impaired mucociliary clearance results in otosinopulmonary disease. Importantly, approximatel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3b5514ace8d91203c68da060b7c2d1
https://pubmed.ncbi.nlm.nih.gov/36074124
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7
Daw1 regulates the timely onset of cilia motility during development
Autor: Elizabeth A. Bearce, Zoe H. Irons, Samuel B. Craig, Colin J. Kuhns, Cynthia Sabazali, Dylan R. Farnsworth, Adam C. Miller, Daniel T. Grimes
Publikováno v: Development (Cambridge, England). 149(12)
Motile cilia generate cell propulsion and extracellular fluid flows that are crucial for airway clearance, fertility and left-right patterning. Motility is powered by dynein arm complexes that are assembled in the cytoplasm then imported into the cil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afff6af1d277a704c83b96ab55dd1bb7
https://pubmed.ncbi.nlm.nih.gov/35708608
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