Water footprints of cities – indicators for sustainable consumption and production

Autor: H. Hoff, P. Döll, M. Fader, D. Gerten, S. Hauser, S. Siebert

Publikováno v: Hydrology and Earth System Sciences, Vol 18, Iss 1, Pp 213-226 (2014)

Water footprints have been proposed as sustainability indicators, relating the consumption of goods like food to the amount of water necessary for their production and the impacts of that water use in the source regions. We further developed the exis

Externí odkaz: https://doaj.org/article/cdfb9d549c6346dfb4dfa1084ca0062c

Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form

Autor: Thomas Ihle Aarhus, Frithjof Bjørnstad, Camilla Wolowczyk, Kristin Uhlving Larsen, Line Rognstad, Trygve Leithaug, Anke Unger, Peter Habenberger, Alexander Wolf, Geir Bjørkøy, Clare Pridans, Jan Eickhoff, Bert Klebl, Bård H. Hoff, Eirik Sundby

Publikováno v: Aarhus, T I, Bjørnstad, F, Wolowczyk, C, Larsen, K U, Rognstad, L, Leithaug, T, Unger, A, Habenberger, P, Wolf, A, Bjørkøy, G, Pridans, C, Eickhoff, J, Klebl, B, Hoff, B H & Sundby, E 2023, ' Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form ', Journal of Medicinal Chemistry, vol. 66, no. 10, pp. 6959-6980 . https://doi.org/10.1021/acs.jmedchem.3c00428

Colony-stimulating factor-1 receptor (CSF1R) is a receptor tyrosine kinase that controls the differentiation and maintenance of most tissue-resident macrophages, and the inhibition of CSF1R has been suggested as a possible therapy for a range of huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eadb975b45033dbb1fd91897a1eaf34
https://hdl.handle.net/20.500.11820/1b3ebb9b-cf94-456a-948e-bbbf0e0e8792

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A Framework for Aquatic Invasive Species Surveillance Site Selection and Prioritization in the US waters of the Laurentian Great Lakes

Autor: Timothy Strakosh, Andrew Tucker, Stephen Hensler, Joel C. Hoffman, Sarah Lesage, Michael H. Hoff, Alisha D. Davidson, Erika Jensen, Donna R. Kashian, Jon M. Bossenbroek, Gust Annis, Lindsay Chadderton

Publikováno v: Manag Biol Invasion

Risk-based prioritization for early detection monitoring is of utmost importance to prevent and mitigate invasive species impacts. The Great Lakes Water Quality Agreement, a binational commitment between the United States and Canada to restore and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682136fc25fb870a977f786367ef58ff
https://pubmed.ncbi.nlm.nih.gov/36072892

Understanding the transgression of global and regional freshwater planetary boundaries

Autor: A. V. Pastor, H. Biemans, W. Franssen, D. Gerten, H. Hoff, F. Ludwig, P. Kabat

Publikováno v: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 380 (2022) 2238
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 380(2238)

Freshwater ecosystems have been degraded due to intensive freshwater abstraction. Therefore, environmental flow requirements (EFRs) methods have been proposed to maintain healthy rivers and/or restore river flows. In this study, we used the Variable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222720ed7e35e795d0896db8f4b39113
https://research.wur.nl/en/publications/understanding-the-transgression-of-global-and-regional-freshwater